DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp6 and ARP6

DIOPT Version :9

Sequence 1:	NP_511165.1	Gene:	Arp6 / 32514	FlyBaseID:	FBgn0011741	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_566861.1	Gene:	ARP6 / 823150	AraportID:	AT3G33520	Length:	421	Species:	Arabidopsis thaliana

Alignment Length:	424	Identity:	143/424 - (33%)
Similarity:	223/424 - (52%)	Gaps:	46/424 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MANAVVVLDNGAHTAKVGLANQDEP-HVVPNCIMKAKSERRRAFV-----GNQIDECRDTSALYY 59
            |:| :||||||....|.|...:.:| .|:|||:.|..|.::  |:     ....||...|||...
plant     1 MSN-IVVLDNGGGLIKAGQGGERDPTTVIPNCLYKPLSSKK--FIHPSPLTTLSDEIDLTSAAVR 62

  Fly    60 ILAFQRGYLLNWHTQKTVWDYIFSKDGIGCSL-----ENRNIVITEPQMNFQSIQEATLEILFEE 119
             ....||||:|...|:.:|.::|:      ||     .:.::::||..::..|:|..|.|::||:
plant    63 -RPIDRGYLINSDLQREIWSHLFT------SLLHIAPSSSSLLLTEAPLSIPSVQRTTDELVFED 120

  Fly   120 YKVDGVYKTTAADLAAFNYVADSEERTTMESLNC-IIIDVGYSFTHVVPFVLGRRVLQGIRRIDM 183
            :....:|......|... |.|..:..:.:....| :::|.|:||||.||.:....:...|:|||:
plant   121 FGFSSLYIAHPQSLVHL-YEASRQPDSILSKTQCSLVVDCGFSFTHAVPVLHNFTLNHAIKRIDL 184

  Fly   184 GGKALTNQLKELISYRHLNVMDESHVVNQIKEDVCFVAEDFKQAMQVHYSEEKRREVTVDYVLPD 248
            ||||.||.||||:|||.:|||||:.:|:..||.:|||:.|..:.:::  :......:...|||||
plant   185 GGKAFTNYLKELVSYRSINVMDETFLVDDAKEKLCFVSLDLLRDLRL--ARNGNTLIKSTYVLPD 247

  Fly   249 FTTVKRGYVRVP---------------------GKPREDEEQQQMVSLCNERFTVPELLFNPSDI 292
            ..|..:|||:.|                     |:.::.:..:..:.|.||||.|||.||.|:|:
plant   248 GVTHTKGYVKDPQAAKRFLSLSEKESVVVMDKVGERKKADMNKNEIDLTNERFLVPETLFQPADL 312

  Fly   293 GVQQVGIPEAVADCLKACPWEAHRELLLNILIVGGSAQFPGFLPRLKRDLRALVPDDLEVSLICP 357
            |:.|.|:.|.:...:.:|.......|..:|::.|||..||....||:.:||.||||..:|.:...
plant   313 GMNQAGLAECIVRAINSCHSYLQPVLYQSIILTGGSTLFPQLKERLEGELRPLVPDHFDVKITTQ 377

  Fly   358 EDPVRYAWYGGKEVATSPNFEEFVYTQDDYEEYG 391
            |||:...|.||..:|:||:||....|:.:|||.|
plant   378 EDPILGVWRGGSLLASSPDFESMCVTKAEYEELG 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp6	NP_511165.1	ACTIN	3..398	CDD:214592	142/422 (34%)
Arp6	NP_511165.1	COG5277	6..391	CDD:227602	140/417 (34%)
ARP6	NP_566861.1	ACTIN	3..420	CDD:214592	142/422 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	233	1.000	Domainoid score	I634
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6451
Inparanoid	1	1.050	234	1.000	Inparanoid score	I1122
OMA	1	1.010	-	-		QHG54227
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	1	1.000	-	-		FOG0005146
OrthoInspector	1	1.000	-	-		oto4057
orthoMCL	1	0.900	-	-		OOG6_103780
Panther	1	1.100	-	-	LDO	PTHR11937
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3663
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.940