Protein Alignment Arp6 and ACTL8

DIOPT Version :9

• Sequence 1: NP_511165.1
• Gene: Arp6 / 32514
• FlyBaseID: FBgn0011741
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_110439.2
• Gene: ACTL8 / 81569
• HGNCID: 24018
• Length: 366
• Species: Homo sapiens
• Alignment Length: 413
• Identity: 99/413 - (23%)
• Similarity: 174/413 - (42%)
• Gaps: 73/413 - (17%)

  Fly     1 MANAVVVLDNGAHTAKVGLANQDEPHVV-PNCI--MKAKSE------RRRAFVGNQIDECRDTSA 56
            ||...|::|:|:...|.|.|..:||.:| ||.:  :..|..      |||..:|  ||.|...:.
Human     1 MAARTVIIDHGSGFLKAGTAGWNEPQMVFPNIVNYLPCKENPGPSYARRRVSLG--IDICHPDTF 63

  Fly    57 LYYILAFQRGYLLNWHTQKTVWDYIFSKDGIGCSLENRN-------IVITEPQMNFQSIQEATLE 114
            .|.|   :||.:|||...:.:|.::         |||..       ::|||..:...:.::..||
Human    64 SYPI---ERGRILNWEGVQYLWSFV---------LENHRREQEVPPVIITETPLREPADRKKMLE 116

  Fly   115 ILFEEYKVDGVYKTTAADLAAFNYVADSEERTTMES--LNCIIIDVGYSFTHVVPFVLGRRVLQG 177
            ||||...|..|            .:||..:.:...|  |..:::|.||..|.|.||..||.:...
Human   117 ILFELLHVPSV------------LLADQLQMSLYASGLLTGVVVDSGYGLTRVQPFHQGRPLPAS 169

  Fly   178 IRRIDMGGKALTNQL-----KELISYRHLNVMDESHVVNQIKEDVCFVAEDFKQAMQVHYSEEKR 237
            .:.::..|:.|:..|     ||....|.|..: |:..|.|:.:  |:|.::..:|:.....::..
Human   170 GKTLEFAGQDLSAYLLKSLFKEDCDRRCLFQL-ETVAVTQMNK--CYVPQNLGEALDFRERQQSA 231

  Fly   238 REVTVDYVLPDFTTVKRGYVRVPGKPREDEEQQQMVSLCNERFTVPELLFNPSDIGVQQVGIPEA 302
            .:.:..|.|||.:.|:                     |...:...||:.|:|.........||.|
Human   232 LDESNTYQLPDGSRVE---------------------LTPMQRVAPEMFFSPQVFEQPGPSIPRA 275

  Fly   303 VADCLKACPWEAHRELLLNILIVGGSAQFPGFLPRLKRDLRALVPDDLEVSLICPEDPVRYAWYG 367
            :.:.:::|.......|:.:::..||:..:|||..||.|:|........:.::....:.....|.|
Human   276 IVESVESCEISLRPLLVSHVMACGGNTLYPGFTKRLFRELMGDHVSSTKATVWEGSNRNFSVWLG 340

  Fly   368 GKEVATSPNFEEFVYTQDDYEEY 390
            ...||....::....::::|.|:
Human   341 ASVVAHLSTYQSEWMSREEYGEH 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp6	NP_511165.1	ACTIN	3..398	CDD:214592	97/411 (24%)
		COG5277	6..391	CDD:227602	97/408 (24%)
ACTL8	NP_110439.2	ACTIN	4..363	CDD:214592	96/408 (24%)
		NBD_sugar-kinase_HSP70_actin	7..362	CDD:302596	95/404 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010