Protein Alignment Arp6 and ACTR6

DIOPT Version :9

• Sequence 1: NP_511165.1
• Gene: Arp6 / 32514
• FlyBaseID: FBgn0011741
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_071941.1
• Gene: ACTR6 / 64431
• HGNCID: 24025
• Length: 396
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 186/393 - (47%)
• Similarity: 268/393 - (68%)
• Gaps: 17/393 - (4%)

  Fly     6 VVLDNGAHTAKVGLANQDEPHVVPNCIMKAKSERRRAFVGNQIDECRDTSALYYILAFQRGYLLN 70
            :||||||:.||:|.:::: ..|:|||..::|:.|.:.|..|||||.:|.|.|:|||.||:|||:|
Human     4 LVLDNGAYNAKIGYSHEN-VSVIPNCQFRSKTARLKTFTANQIDEIKDPSGLFYILPFQKGYLVN 67

  Fly    71 WHTQKTVWDYIFSKDGIGCSLENRNIVITEPQMNFQSIQEATLEILFEEYKVDGVYKTTAADLAA 135
            |..|:.||||:|.|:.......:.||:||||..||.||||:..|||||||:...|.:..|..|:|
Human    68 WDVQRQVWDYLFGKEMYQVDFLDTNIIITEPYFNFTSIQESMNEILFEEYQFQAVLRVNAGALSA 132

  Fly   136 FNYVADSEERTTMESLNCIIIDVGYSFTHVVPFVLGRRVLQGIRRIDMGGKALTNQLKELISYRH 200
            ..|..|:.     ..|.|||:|.||||||:||:...::..:.|.||::|||.|||.|||:||||.
Human   133 HRYFRDNP-----SELCCIIVDSGYSFTHIVPYCRSKKKKEAIIRINVGGKLLTNHLKEIISYRQ 192

  Fly   201 LNVMDESHVVNQIKEDVCFVAEDFKQAMQVHYSEEKRREVTVDYVLPDFTTVKRGYVRVPGKPRE 265
            |:||||:||:||:|||||:|::||.:.|.:...:.:...|.:|||||||:|:|:|:.    ||||
Human   193 LHVMDETHVINQVKEDVCYVSQDFYRDMDIAKLKGEENTVMIDYVLPDFSTIKKGFC----KPRE 253

  Fly   266 D-------EEQQQMVSLCNERFTVPELLFNPSDIGVQQVGIPEAVADCLKACPWEAHRELLLNIL 323
            :       :..:|::.|.||||.|||:||||||||:|::|||||:...::..|.|.......||:
Human   254 EMVLSGKYKSGEQILRLANERFAVPEILFNPSDIGIQEMGIPEAIVYSIQNLPEEMQPHFFKNIV 318

  Fly   324 IVGGSAQFPGFLPRLKRDLRALVPDDLEVSLICPEDPVRYAWYGGKEVATSPNFEEFVYTQDDYE 388
            :.||::.||||..|:..::|.|.|.|.:||::.||:|:.|||.|||.::.:.:||:.|.|::|||
Human   319 LTGGNSLFPGFRDRVYSEVRCLTPTDYDVSVVLPENPITYAWEGGKLISENDDFEDMVVTREDYE 383

  Fly   389 EYG 391
            |.|
Human   384 ENG 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp6	NP_511165.1	ACTIN	3..398	CDD:214592	186/393 (47%)
		COG5277	6..391	CDD:227602	185/391 (47%)
ACTR6	NP_071941.1	ACTIN	2..394	CDD:214592	186/393 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145068
Domainoid	1	1.000	383	1.000	Domainoid score	I824
eggNOG	1	0.900	-	-		E1_KOG0680
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6451
Inparanoid	1	1.050	384	1.000	Inparanoid score	I2050
Isobase	1	0.950	-	0.861654	Normalized mean entropy	S1456
OMA	1	1.010	-	-		QHG54227
OrthoDB	1	1.010	-	-		D462325at33208
OrthoFinder	1	1.000	-	-		FOG0005146
OrthoInspector	1	1.000	-	-		oto90805
orthoMCL	1	0.900	-	-		OOG6_103780
Panther	1	1.100	-	-	LDO	PTHR11937
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R85
SonicParanoid	1	1.000	-	-		X3663
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750