DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp6 and si:ch211-241j12.3

DIOPT Version :9

Sequence 1:	NP_511165.1	Gene:	Arp6 / 32514	FlyBaseID:	FBgn0011741	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	XP_017207998.2	Gene:	si:ch211-241j12.3 / 566552	ZFINID:	ZDB-GENE-040724-72	Length:	1245	Species:	Danio rerio

Alignment Length:	400	Identity:	113/400 - (28%)
Similarity:	183/400 - (45%)	Gaps:	54/400 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VVLDNGAHTAKVGLANQDEPHVV-PNCIMKAKSER-------RRAFVGNQIDECRDTSALYYILA 62
            :|||:|:...|.|.|:||.|..| |..|.:.|.|.       |..:||:.....|....|.|  .
Zfish   881 IVLDSGSGLMKAGFADQDLPAAVFPTVIGRPKYEEVMNSCVDRELYVGHDAQHMRGVLTLRY--P 943

  Fly    63 FQRGYLLNWHTQKTVWDYIFSKDGIGCSLENRNIVITEPQMNFQSIQEATLEILFEEYKVDGVYK 127
            .:.|.:.||...:.:|.:.|..  :..:.|:..:::||..:|....::..:|::||.:.|...:.
Zfish   944 IRHGVVSNWDEMEMLWTHAFQL--LSAAPEDHPVLLTEAALNPLQNRQRMVELMFEAFSVPLTFV 1006

  Fly   128 TTAADLAAFNYVADSEERTTMESLNCIIIDVGYSFTHVVPFVLGRRVLQGIRRIDMGGKALTNQL 192
            ...|.||.:     :..|||     .:::|.|...:|.||...|..:...::|:|:.|..:|.||
Zfish  1007 AVQAVLALY-----ASGRTT-----GVVLDSGDGVSHSVPVFEGYCLPHAVQRLDLAGADVTLQL 1061

  Fly   193 KELI--SYRHLNVMDESHVVNQIKEDVCFVAEDFKQAMQVHYSEEKRREVTVDYVLPDFTTVKRG 255
            ::|:  |...|....|..:|.::||..|||:.|::       :|.|..|..:.|.|||..|
Zfish  1062 QKLLLESGVCLRTSAELEIVREMKERCCFVSVDYE-------AEMKSSESEIQYTLPDGHT---- 1115

  Fly   256 YVRVPGKPREDEEQQQMVSLCNERFTVPELLFNPSDIGVQQVGIPEAVADCLKACPWEAHRELLL 320
                             |.|.::||..||:||.|..||....|:.|:|...:.....:..|..:.
Zfish  1116 -----------------VPLASQRFRAPEILFRPELIGRDHYGLHESVFRSILQSDLDLRRSFVG 1163

  Fly   321 NILIVGGSAQFPGFLPRLKRDLRALVPDDLE--VSLICPEDPVRYAWYGGKEVATSPNFEEFVYT 383
            |||:.||:....|...||:.::||:||.||.  |.:..|.|.....|.||..:|:.|..:....:
Zfish  1164 NILLSGGNTLLSGLAERLQLEVRAMVPLDLSACVRVSSPPDRDFSVWSGGAALASLPEQQSAWIS 1228

  Fly   384 QDDYEEYGFQ 393
            ..:|||:|.|
Zfish  1229 AAEYEEFGPQ 1238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp6	NP_511165.1	ACTIN	3..398	CDD:214592	112/399 (28%)
Arp6	NP_511165.1	COG5277	6..391	CDD:227602	111/396 (28%)
si:ch211-241j12.3	XP_017207998.2	Neuromodulin_N	<411..625	CDD:331332
si:ch211-241j12.3	XP_017207998.2	ACTIN	878..1245	CDD:214592	112/399 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920