DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp6 and Actl6a

DIOPT Version :9

Sequence 1:	NP_511165.1	Gene:	Arp6 / 32514	FlyBaseID:	FBgn0011741	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_001034122.1	Gene:	Actl6a / 361925	RGDID:	1307747	Length:	429	Species:	Rattus norvegicus

Alignment Length:	437	Identity:	96/437 - (21%)
Similarity:	188/437 - (43%)	Gaps:	67/437 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VVLDNGAHTAKVGLANQDEPHVVPNCIMKAKSERRRAFVGNQIDECR----------DTSALYY- 59
            :|.|.|::|.:.|.|.:|.|.|.....:....||.......:||..:          ||:||..
  Rat    14 LVFDIGSYTVRAGYAGEDCPKVDFPTAIGVVLERDDGSTMMEIDGDKGKQGGPTYYIDTNALRVP 78

  Fly    60 ------ILAFQRGYLLNWHTQKTVWDYIFSKDGIGCSLENRNIVITEPQMNFQSIQEATLEILFE 118
                  |...:.|.:.:|.:.:.:.|:.: |..:........::::|...|.::.:|...|::||
  Rat    79 RESMEAISPLKNGMVEDWDSFQAILDHTY-KMHVKSEASLHPVLMSEAPWNTRAKREKLTELMFE 142

  Fly   119 EYKVDGVYKTTAADLAAFNYVADSEERTTMESLNCIIIDVGYSFTHVVPFVLGRRVLQGIRRIDM 183
            .|.:...:....|.|.||     :..|:|     .:|:|.|.:.|..:|...|..:.|||.:..:
  Rat   143 HYSIPAFFLCKTAVLTAF-----ANGRST-----GLILDSGATHTTAIPVHDGYVLQQGIVKSPL 197

  Fly   184 GGKALTNQLKELISYRHLNVMDESHVVNQIKEDVCFVAEDFKQAMQVHYS-EEKRREVTVDY--- 244
            .|..:|.|.:||....::.::....:.::         |..::....::. :||..:||..:
  Rat   198 AGDFITMQCRELFQEMNIELIPPYMIASK---------EAVREGSPANWKRKEKLPQVTRSWHNY 253

  Fly   245 ----VLPDFTTVKRGYVRVPGKPREDEEQQQMVSL---------CN---ERFTVPELLFNPSDI- 292
                |:.||   :...::|.....:::...||.::         |:   ||..:||.||:||::
  Rat   254 MCNCVIQDF---QASVLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGLFDPSNVK 315

  Fly   293 ---GVQQVGIPEAVADCLKACPWEAHRELLLNILIVGGSAQFPGFLPRLKRDLRALVPDDLEVSL 354
               |...:|:...|...:..|..:....|..::::.||:.....|..||.|:|....|..:.:.|
  Rat   316 GLSGNTMLGVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMRLKL 380

  Fly   355 ICPEDPV--RY-AWYGGKEVATSPNFEEFVYTQDDYEEYGFQGINQR 398
            |.....|  |: :|.||..:|:...|::...::.:|||.|.|.:.::
  Rat   381 IANNTTVERRFSSWIGGSILASLGTFQQMWISKQEYEEGGKQCVERK 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp6	NP_511165.1	ACTIN	3..398	CDD:214592	96/435 (22%)
Arp6	NP_511165.1	COG5277	6..391	CDD:227602	94/428 (22%)
Actl6a	NP_001034122.1	Actin	11..429	CDD:394979	96/437 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010