DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp6 and Actl9b

DIOPT Version :9

Sequence 1:	NP_511165.1	Gene:	Arp6 / 32514	FlyBaseID:	FBgn0011741	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_001013915.1	Gene:	Actl9b / 292516	RGDID:	1359476	Length:	411	Species:	Rattus norvegicus

Alignment Length:	396	Identity:	102/396 - (25%)
Similarity:	175/396 - (44%)	Gaps:	50/396 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VVLDNGAHTAKVGLANQDEPHVVPNCIMKAKSERR--------RAFVGNQIDECRDTSALYYILA 62
            ||:|.|....|:|.|.|..|..:...|:..:.:||        ..|:|.......:.:.::.:
  Rat    47 VVIDMGTGICKMGFAGQTRPTYIVRNIVGCQPKRRTTMEQPKMEMFIGEAAHARPELTLMHPV-- 109

  Fly    63 FQRGYLLNWHTQKTVWDYIFSKDGIGCSLENRNIVITEPQMNFQSIQEATLEILFEEYKVDGVYK 127
             :.|.:::|...:.:|.:|...| :....::..::.|:|..|..|.:|..:|:.||......:|.
  Rat   110 -RNGIVVDWEAAEFIWRHILEND-LRLDTQDHPLLFTDPPFNPASNREKLVEVAFESLHSPAIYV 172

  Fly   128 TTAADLAAFNYVADSEERTTMESLNCIIIDVGYSFTHVVPFVLGRRVLQGIRRIDMGGKALTNQL 192
            .:.:.|:.:   |:..       :|.:::|.|:..::.||...|..:..||:|:|:.|..||..|
  Rat   173 ASQSVLSVY---ANGR-------VNGLVVDTGHGVSYTVPVFQGYNLPSGIQRMDLAGHYLTKFL 227

  Fly   193 KELISYRHLNVMDES-HVVNQIKEDVCFVAEDFKQAMQVHYSEEKRREVTVDYVLPDFTTVKRGY 256
            .|.|......|..|. ..:..||:..|:||.|| |..|....|:.||.:.    |||
  Rat   228 AEKILRSSFAVKKEDMDTMENIKQQYCYVALDF-QKEQGRPDEKFRRCLK----LPD-------- 279

  Fly   257 VRVPGKPREDEEQQQMVSLCNERFTVPELLFNPSDI-GVQQVGIPEAVADCLKACPWEAHRELLL 320
                         .||:::..|.|..|||||:|.|. |...:|:|..|...|...|.|...::..
  Rat   280 -------------GQMITVGKELFQCPELLFHPPDTSGPSSLGLPSMVEHSLSTVPQELRADMEQ 331

  Fly   321 NILIVGGSAQFPGFLPRLKRDLRALVPDDLEVSLICPEDPVRYAWYGGKEVATSPNFEEFVYTQD 385
            |:|:.|||:.|.||..|.|.:|...:..:..|.::...:.....|.||..:|:...|:.....::
  Rat   332 NVLLCGGSSLFTGFEGRFKTELLRRLGPEAHVVVVAQANRNLSVWIGGSILASLCAFQTRWVLRE 396

  Fly   386 DYEEYG 391
            .|||:|
  Rat   397 QYEEHG 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp6	NP_511165.1	ACTIN	3..398	CDD:214592	102/396 (26%)
Arp6	NP_511165.1	COG5277	6..391	CDD:227602	101/394 (26%)
Actl9b	NP_001013915.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23
		NBD_sugar-kinase_HSP70_actin	45..410	CDD:302596	102/396 (26%)
		Actin	47..411	CDD:278451	102/396 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010