DRSC/TRiP Functional Genomics Resources

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Protein Alignment Arp6 and Actr1b

DIOPT Version :9

Sequence 1:NP_511165.1 Gene:Arp6 / 32514 FlyBaseID:FBgn0011741 Length:398 Species:Drosophila melanogaster
Sequence 2:NP_666219.1 Gene:Actr1b / 226977 MGIID:1917446 Length:376 Species:Mus musculus


Alignment Length:408 Identity:109/408 - (26%)
Similarity:191/408 - (46%) Gaps:50/408 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MANAVVVLDNGAHTAKVGLANQDEP-HVVPNCIMKAKSERRRA-------FVGNQIDECRDTSAL 57
            :||..||:|||:...|.|.|....| :..||.:.:.|..|..|       |:|.:.:|.|....:
Mouse     7 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGPKAEEHRGLLTI 71

  Fly    58 YYILAFQRGYLLNWHTQKTVWDYIFSKDGIGCSLENRNIVITEPQMNFQSIQEATLEILFEEYKV 122
            .|  ..:.|.:.:|:..:.:|.|::|||.:....|...:::||..:|....:|...|:.||.:.|
Mouse    72 RY--PMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNV 134

  Fly   123 DGVYKTTAADLAAFNYVADSEERTTMESLNCIIIDVGYSFTHVVPFVLGRRVLQGIRRIDMGGKA 187
            ..::.:..|.|:.:     :..|||     .:::|.|...||.||...|..:...|.|:|:.|:.
Mouse   135 PALFISMQAVLSLY-----ATGRTT-----GVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRD 189

  Fly   188 LTNQLKELISYR--HLNVMDESHVVNQIKEDVCFVAEDFKQAMQVHYSEEKRREVTVDYVLPDFT 250
            ::..|:.|:...  ..:...|..||..|||..|:::.:.::       :|......|.|.|||.:
Mouse   190 VSRYLRLLLRKEGADFHTSAEFEVVRTIKERACYLSINPQK-------DEALETEKVQYTLPDGS 247

  Fly   251 TVKRGYVRVPGKPREDEEQQQMVSLCNERFTVPELLFNPSDIGVQQVGIPEAVADCLKACPWEAH 315
            |:..|    |.                 ||..|||||.|..:|.:..|:.|.:|..:.....:..
Mouse   248 TLDVG----PA-----------------RFRAPELLFQPDLVGDESEGLHEVLAFAIHKSDMDLR 291

  Fly   316 RELLLNILIVGGSAQFPGFLPRLKRDLRALVPDDLEVSLICPEDPVRYAWYGGKEVATSPNFEEF 380
            |.|..||::.|||..|.||..||..:::.|.|.|:::.:..|::.:...|.||..:|:...|::.
Mouse   292 RTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIKISAPQERLYSTWIGGSILASLDTFKKM 356

  Fly   381 VYTQDDYEEYGFQGINQR 398
            ..::.:|||.|.:.|:::
Mouse   357 WVSKKEYEEDGSRAIHRK 374

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Arp6NP_511165.1 ACTIN 3..398 CDD:214592 108/404 (27%)
COG5277 6..391 CDD:227602 105/394 (27%)
Actr1bNP_666219.1 NBD_sugar-kinase_HSP70_actin 5..376 CDD:418402 109/408 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D649708at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

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