Protein Alignment Arp6 and ACTRT1

DIOPT Version :10

• Sequence 1: NP_511165.1
• Gene: Arp6 / 32514
• FlyBaseID: FBgn0011741
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_612146.1
• Gene: ACTRT1 / 139741
• HGNCID: 24027
• Length: 376
• Species: Homo sapiens
• Alignment Length: 403
• Identity: 96/403 - (23%)
• Similarity: 185/403 - (45%)
• Gaps: 50/403 - (12%)

  Fly     6 VVLDNGAHTAKVGLANQDEP-HVVPNCIMKAKSE------RRRAFVGNQIDECRDTSALYYILAF 63
            |:.|||:...|.||:.:..| ||:.:.:...|..      .::.|||.:.....:...|:|  ..
Human    12 VIFDNGSGLCKAGLSGEIGPRHVISSVLGHCKFNVPLARLNQKYFVGQEALYKYEALHLHY--PI 74

  Fly    64 QRGYLLNWHTQKTVWDYIFSKDGIGCSLENRNIVITEPQMNFQSIQEATLEILFEEYKVDGVYKT 128
            :||.:..|...:.:|.::|.:: :|.....:.:::|||.:|.:.|:|...|::||.:.|.|.|.:
Human    75 ERGLVTGWDDMEKLWKHLFERE-LGVKPSQQPVLMTEPSLNPREIREKLAEMMFETFSVPGFYLS 138

  Fly   129 TAADLAAFNYVADSEERTTMESLNCIIIDVGYSFTHVVPFVLGRRVLQGIRRIDMGGKALTNQLK 193
            ..|..|.:          ....:..:::|.|...|..||...|..:...:.::.|.|:.:|..|.
Human   139 NHAVAALY----------ASACVTGLVVDSGDGVTCTVPIFEGYSLPHAVTKLCMAGRDITEHLT 193

  Fly   194 ELISYRHLN---VMDESHVVNQIKEDVCFVAEDFKQAMQVHYSEEKRREVTVDYVLPDFTTVKRG 255
            .|:.....|   ::::: |||.|||.:|::|.:.::.::     :.|.||...|.|||      |
Human   194 RLLFASGFNFPCILNKA-VVNNIKEKLCYIALEPEKELR-----KSRGEVLGAYRLPD------G 246

  Fly   256 YVRVPGKPREDEEQQQMVSLCNERFTVPELLFNPSDIGVQQVGIPEAVADCLKACPWEAHRELLL 320
            :|               :...:|.:.|||:||.|..:|:...|:.:.|:..:..|..:...:|..
Human   247 HV---------------IHFGDELYQVPEVLFAPDQLGIHSPGLSKMVSSSIMKCDTDIQNKLYA 296

  Fly   321 NILIVGGSAQFPGFLPRLKRDLRALVPDDLEVSLICPEDPVRYAWYGGKEVATSPNFEEFVYTQD 385
            :|::.||:...||...||.:::..|......:.:....|....||.|...:.:..:|::...|..
Human   297 DIVLSGGTTLLPGLEERLMKEVEQLASKGTPIKITASPDRCFSAWIGASIMTSMSSFKQMWVTSA 361

  Fly   386 DYEEYGFQGINQR 398
            |::|||...:.:|
Human   362 DFKEYGTSVVQRR 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp6	NP_511165.1	ASKHA_NBD_Arp6	5..391	CDD:466816	93/394 (24%)
ACTRT1	NP_612146.1	ASKHA_NBD_actin_Arp-T1-3	10..367	CDD:466848	93/394 (24%)