Protein Alignment HUWE1 and UPL1

DIOPT Version :9

• Sequence 1: NP_001285288.1
• Gene: HUWE1 / 32510
• FlyBaseID: FBgn0030674
• Length: 5151
• Species: Drosophila melanogaster
• Sequence 2: NP_001185245.1
• Gene: UPL1 / 842036
• AraportID: AT1G55860
• Length: 3681
• Species: Arabidopsis thaliana
• Alignment Length: 5422
• Identity: 1113/5422 - (20%)
• Similarity: 1837/5422 - (33%)
• Gaps: 2024/5422 - (37%)

  Fly     9 KKGSSELTAECRELIDELTKRRTRAELLEFLDTVHV------WIYGKCELYHWIEILDRFDKILE 67
            ::.:||:.::.:..|:.:|...        |:.:|.      |.:.|.:.:||:::.:.||...|
plant     5 RRRASEVPSKIKSFINSVTSVP--------LELIHEPLACFRWEFDKGDFHHWVDLFNYFDTFFE 61

  Fly    68 EASRHVNGNEFVLQCDTNFQETDVTL----LLHVLNFTTLLIEHSFSRHLYNSIE-HLTVLLSSQ 127
               :||...: .|..:.||:|:|...    :|.||....:::|:..::|.|:|.| ||::||:|.
plant    62 ---KHVQVRK-DLHIEENFEESDPPFPKDAVLQVLRVIRVVLENCTNKHFYSSYEQHLSLLLAST 122

  Fly   128 NMDIVLAVLNLLYMFSKRSNFIPRLPFEKKELLIVKLFNIAERWGDPNYGLSLKDCC----IGEP 188
            :.|:|.|.|..|..|.||.  |.:... :...|..|||::|:.||....||.|..|.    ..:.
plant   123 DADVVEACLQTLAAFLKRQ--IGKYSI-RDASLNSKLFSLAQGWGGKEEGLGLTSCAAENSCDQV 184

  Fly   189 KLEFLYQLCIDYV--DEH-----GHAAQLEIPDMMDLCHTASAPEVIKTIAGQISKPSEAIKMRI 246
            .|:....|..::.  ||.     |....:.:|| :.:|..:....:.|.:......||  ::..:
plant   185 SLQLGRTLHFEFYPSDESPSELPGGLQVIHVPD-VSICAESDLELLNKLVIDHNVPPS--LRFAL 246

  Fly   247 AHRVRLISGFNNYKLRLQFVQARLQAVSILIYSNALQDNTDKVLYAGFGE-----ELCELIDKED 306
            ..|:|....|::...|.||...||.|..:|:.::.   :|:.|:....||     ||..|:..||
plant   247 LTRMRFARAFSSLATRQQFTCIRLYAFVVLVQASG---DTENVVSFFNGEPEFVNELVTLVSYED 308

  Fly   307 VHLVEIRAAVLRTLTSMLH-FDRNPNVPRAGSRLMKIVHYTGAERQGGTLPLLVRDCIDNLTTHG 370
            ....:||...|.:|.::.. ..|.|.|..|.:        :|..|  |.|..|::..||::..
plant   309 TVPEKIRILCLLSLVALSQDRTRQPTVLTAVT--------SGGHR--GLLSGLMQKAIDSVVC-- 361

  Fly   371 LTERYPLILATSLFSLLYHLASYEMGGTALVKSGMMQSLLCVISWPGVDLEHITFVTRAVRVIDL 435
            :|.::.|..|.:|.||:..|.|...|.:|:.::|::.:|:.:|.  ..|.:|:..|:.||.:::.
plant   362 ITSKWSLAFAEALLSLVTVLVSSSSGCSAMREAGLIPTLVPLIK--DTDPQHLHLVSAAVHILEA 424

  Fly   436 I---TNIDIARFHQNNGLNVFIDRLEKEIKSCCKALADIGITLKESTLRDDHKLDTSLDHVDEDV 497
            .   :|...|.|....||:..|.||:.|:                             ...::||
plant   425 FMDYSNPAAALFRDLGGLDDTIFRLKLEV-----------------------------SRTEDDV 460

  Fly   498 EDGSGENASVTSGNASPRRDNSSDGATGAGSIVYRAYHEHIGGAGSGAGLLDIGGARSSLSGGSS 562
            ::                ::.|||                                       |:
plant   461 KE----------------KNCSSD---------------------------------------SN 470

  Fly   563 GTSGMGAGSINRDGSAARPPAIMYPTNSYYARPLAERKAELSSQLPSSLAPKKPSCVTQRAALLK 627
            |..                                      :.|||.|.|    .....|..|||
plant   471 GPD--------------------------------------TEQLPYSEA----LISYHRRLLLK 493

  Fly   628 SMLNFLKKSIQDHA-HFSNMRNIMETSLTQSLRHIIANAEYYGPSLFLLATDVVTVYVFNEPSLL 691
            ::|..:  |:..:| ..:|:....|:.|.:.|..|...|:.:|..:|.||..|::..:..:|:..
plant   494 ALLRAI--SLGTYAPGNTNLYGSEESLLPECLCIIFRRAKDFGGGVFSLAATVMSDLIHKDPTCF 556

  Fly   692 SSLQDLGITSVMLKALLQKDVPATREVLGSLPNVFSALCLNERGLFEFLSYDPFDKVLKVLLSPD 756
            ::|...|:||..|.| :..:|..:.|.:..:|....|||||..||......:.....:|:..||.
plant   557 NALDSAGLTSTFLDA-ISDEVICSAEAITCIPQCLDALCLNNSGLQAVKDRNALRCFVKIFTSPS 620

  Fly   757 YLVAMRRRRSSDPLGDTATNLGNAMDDLIKHHPYLRADATEAIVRLLNELVRLGSDPSFICWRAN 821
            ||.|:        .|||..:|.:.:|:|::|...||....:..:.:||.::.:||         .
plant   621 YLRAL--------TGDTPGSLSSGLDELLRHQSSLRTYGVDMFIEILNSMLIIGS---------G 668

  Fly   822 KESSGSGSGSGSHGGGHHVASTPSPMVMVAGTGSASSVLQGAADTNDSSGDDDDDDDEMSSASQQ 886
            .|::.|.|..        |.::.:|:.|                        :.|.||.|.|...
plant   669 MEATTSKSAD--------VPTSAAPVPM------------------------EIDVDEKSLAVSD 701

  Fly   887 QQQPTTPGQGGGPSTPRTQQAGGVVGSGAGATGTPAAASQAVKVVTPPEREAIPLIDYILNVMKF 951
            :.:|::.                                      |.|....:.|.|.:.||.:.
plant   702 EAEPSSD--------------------------------------TSPANIELFLPDCVCNVARL 728

  Fly   952 IEAIFSNSPNGDHCREFVLHGGLKPILQLLSLPNLPVDSPVSTT-SQAVAN------------VC 1003
            .|.:..|:   :.|..||...|:..:|||.|||.:|:.:.:..: |.|..|            ||
plant   729 FETVLQNA---EVCSLFVEKKGIDAVLQLFSLPLMPLSTSLGQSFSVAFKNFSPQHSAGLARIVC 790

  Fly  1004 KAILSQAQETKVLDVALKQLADIVAQLKPLIKHFTFPGGSVLLAELVCCQRLEDGFANAEYTPIL 1068
            ..:....::||:|.|:::                    |:.||       :||    :|..|.||
plant   791 SYLREHLKKTKILLVSIE--------------------GTQLL-------KLE----SAIQTKIL 824

  Fly  1069 HNMSFVHGYVVMLVHLCRNASNDMRTILLKRWGVNRETGVQLLQQLVQLYISLVWESTILLNLCS 1133
            .::|.:.|.:.:...|.:.:::.:..:......|.:|.|:        .|...:|:    :.||:
plant   825 RSLSCLEGMLSLSNFLLKGSASVISELSAADADVLKELGI--------TYKQTIWQ----MALCN 877

  Fly  1134 DEPTQHPDLIWDEIAAQMSAAAGTADPLTEAELSRKLE---------RAAEFRTKYTPEEQF--- 1186
            |........:.......:||::.||:..::.:.|..|.         |::..::.:..:.:|
plant   878 DTKEDEKKSVDRGSDNSVSASSSTAERESDEDSSNALAVRYTNPVSIRSSSSQSIWGGDREFLSI 942

  Fly  1187 ------------------------RYIKS------------LLAASSRLGR-----ALAELLGTL 1210
                                    |:::|            :.::|..|.:     .:||:|..|
plant   943 VRSGEGIHGRTRHAIARMRGGRTRRHLESFNFDSEIPADLPVTSSSHELKKKSTEVLIAEILNKL 1007

  Fly  1211 --------VKLSVGSPQTRQRRINDLISNITKVPTPEAREIARI-LSSILVNGF----SHESILP 1262
                    ..|..|.....:|||:.  ::::.........:|:: |.::..:|:    .||..|
plant  1008 NCTLRFFFTALVKGFTSANRRRIDG--ASLSSASKTLGTALAKVFLEALNFDGYGAAAGHEKSL- 1069

  Fly  1263 KPVPKLKLTFL---ICSVGFTGPMLFDDKRS-AFHLMISQFCAENGLKAFFEMF------YW--- 1314
                .:|..:|   :..:.|   :.||.:|. .|..|::.|......|.....|      .|
plant  1070 ----SVKCRYLGKVVDDITF---LSFDTRRRVCFTAMVNSFYVHGTFKELLTTFEATSQLLWTVP 1127

  Fly  1315 ----ALSLDNVSQKFEFDQWASMEDLMQSHEDDKRDCPEGTGEFLDAWLQLLEKMVNPRAMLDSP 1375
                |.|.:| .:..|.:.|:..:.|:.:               |..:.:.|:..||      |.
plant  1128 FSIPASSTEN-EKPGERNIWSHSKWLVDT---------------LQNYCRALDYFVN------ST 1170

  Fly  1376 YTMSP----RLNYMPDS---------VPFEPVFYLIHIHQLAMQALRRIWARRPIPNYGPSMFET 1427
            |.:||    :|...|.|         ||.||..::.::....:..:..||.....|:..|:...:
plant  1171 YLLSPTSQTQLLVQPASVGLSIGLFPVPREPETFVRNLQSQVLDVILPIWNHPMFPDCNPNFVAS 1235

  Fly  1428 MILILKHLIKSHQTLLDRYHTRMKEIKFENLYIRSTDDGLNADHIKTLTDMGFMHYHVIEALR-- 1490
            :..::.|:   :..::|....|....:..|.  |:....|:...:..:.:|||.......|||
plant  1236 VTSLVTHI---YSGVVDARENRSGVTRGINQ--RALPLQLDESIVGMIVEMGFSRSRAEIALRRV 1295

  Fly  1491 -TNASLEEATDYLLNNPE---------ASSLSTTGGQSSSSAPPPPPPPSASTMDIDVDVPADGE 1545
             || |:|.|.|:|..|||         |.:|:.:.|.||.:       |.....:..||||.:
plant  1296 GTN-SVEMAMDWLFTNPEQPVQEDDELAQALALSLGNSSET-------PKLEDTEKPVDVPQE-- 1350

  Fly  1546 STQSKSSTSPNSSYDYKHLKLMPSLIFDRFCDEAISRAFEFMEAIPDTVNSAADLIAVLYRRHNH 1610
              :::....|........:||..|       |:  |.||..|           ||...|..|:..
plant  1351 --EAEPKEPPVDEVIAASVKLFQS-------DD--SMAFPLM-----------DLFVTLCNRNKG 1393

  Fly  1611 LNKQVFVTNFVRNI-IQWVDFTLQLFEPAKTTGSKASRLEECLTGMTATRLFVRLKTSTLLLEEN 1674
            .::...|:..::.: :..:||       :|.||              |..:...:....|..::|
plant  1394 EDRPKIVSYLIQQLKLVQLDF-------SKDTG--------------ALTMIPHILALVLSEDDN 1437

  Fly  1675 YSDLHRPLVEAITAQDAMVSLVKLLDCMSQWMLEQSTETNTGQQRATVPRWVQNLVDLIDAIDSI 1739
                    ...|.|||.:|::.  :..::.:.|:..:||     ....|:.:..|: |:     :
plant  1438 --------TREIAAQDGIVTVA--IGILTDFNLKSESET-----EILAPKCISALL-LV-----L 1481

  Fly  1740 SHILQRKANMRAVSSDVWRWYDASTGKWNAYSEANNELIRNAYAAGERWLYINIGRQRCTVSLNC 1804
            |.:||.:..:   ||:              |.|.|
plant  1482 SMMLQAQTKL---SSE--------------YVEGN------------------------------ 1499

  Fly  1805 MTQVSEASGTHRPVCPALKLSEAITSLNNPVALHKVEHILNRVVRTAPDGSGTVHSDELISLRQL 1869
                                                            .|...|.||
plant  1500 ------------------------------------------------QGGSLVPSD-------- 1508

  Fly  1870 VNFTDGQQPQQSENSANPSEEATSEDGPAAANSGSPPATMTTRSKTRQKSAAAAAAAKNKSQSGG 1934
                   .||               |..||.                 |.|.::..||.:|....
plant  1509 -------SPQ---------------DSTAAL-----------------KDALSSDVAKGESNQAL 1534

  Fly  1935 SPPIPKRTQKIILNEEQVGLSKFDCGRIIGSIVDLLQPSHQMLNETKLSLLRLCARLTRNYDNAQ 1999
            .....|.|..:.:.|....| ...||.|...:..::..          ::|:||||||:::..|.
plant  1535 ELIFGKSTGYLTMEEGHKAL-LIACGLIKQHVPAMIMQ----------AVLQLCARLTKSHALAI 1588

  Fly  2000 VFIRRGGVRMLLHLQQACSFMGFPTYANIILRHVLEAPPVLQEAMERVLGMRAAGIVPVGHRDLI 2064
            .|:..||:..|.:|.:.|.|.|:.|.|::|:||::|.|..||.|||..:....:|...:|.....
plant  1589 QFLENGGLSSLFNLPKKCCFPGYDTVASVIVRHLVEDPQTLQIAMETEIRQTLSGKRHIGRVLPR 1653

  Fly  2065 YVLTQVSSAVSRNPQIFVAAAKEMLKGEYLINTNSTTLADDARVMVKSKFGQQPTAAAGGATPHN 2129
            ..||.::..:||:|.:|:.|         :.:|.....:.....::.||..::|..:   .:.|.
plant  1654 TFLTTMAPVISRDPVVFMKA---------VASTCQLESSGGRDFVILSKEKEKPKVS---GSEHG 1706

  Fly  2130 QTPTPPPAAKDELKDDPQVQSSVAVLKELLHGLVQPCWHYGGTGSLDRGQGAAELLQP-DQ---- 2189
            .:...|                :.:.:..||.:...|       |....:..|..:|. ||
plant  1707 FSLNEP----------------LGISENKLHDVSGKC-------SKSHRRVPANFIQVIDQLIDL 1748

  Fly  2190 ----PPGTAQGCHDDELYFRFQETPAPVSSKKQSSSGG--GAAAAGQTGQATEKFEPCCCTWHIP 2248
                |....|  .|.|......|...|.:..|..|..|  ..|::.:.|: .||.|       ||
plant  1749 VLSFPRVKRQ--EDGETNLISMEVDEPTTKVKGKSKVGEPEKASSSRVGE-PEKAE-------IP 1803

  Fly  2249 TSGHTHAKPTISRATLLKLLADSTRAYQSLVPRVL--------LSHVYTPADSP----LISAPQQ 2301
            ......|:.|.    :||||:|....|......:|        |.....|.|||    ||.....
plant  1804 EKSEELARVTF----ILKLLSDIVLMYSHGTSVILRRDTEISQLRGSNLPDDSPGNGGLIYHVIH 1864

  Fly  2302 TFLGVLLDRFL-PITQRHHVPEVSTMTRVLICSLSDCYQQPGVQVHVAEELHAAVARALAQPDSA 2365
            ..|.:.|::|: |...:..:.|.::...|::||.|:..::     .:..||    :|.|:...|.
plant  1865 RLLPISLEKFVGPEEWKEKLSEKASWFLVVLCSRSNEGRK-----RIINEL----SRVLSVFASL 1920

  Fly  2366 EKHTRLQVLMS-----LFPNLIESPMLYDKVHMHRN--------NMYRVLLRQGVMTYLTKVAQY 2417
            .:.:...||:.     .|.||:.|.:..:......|        ::.:.::..|.:..||.:...
plant  1921 GRSSSKSVLLPDKRVLAFANLVYSILTKNSSSSSSNFPGCGCSPDVAKSMMDGGTIQCLTSILHV 1985

  Fly  2418 KDLSNHNTLSTLAAILRPMEILLRFSVSTTTLGSKRILFGSGGPGGPNASGNGNNTAGGSSGNGP 2482
            .||.:.:....:..||:.:|.|.|.:.:...|.|:          .||
plant  1986 IDLDHPDAPKLVTLILKSLETLTRAANAAEQLKSE----------VPN----------------- 2023

  Fly  2483 GSGNTYGTIINRRLYPRLAARTGFGSAMERSNAMGGEHVLRDIIRNVLSDRRHAFEFIFNSDDMA 2547
                                        |:.|        ||      ||.||
plant  2024 ----------------------------EKKN--------RD------SDERH------------ 2034

  Fly  2548 VDSEDAAAPGSGVGGGGSGAGSVGGGVSGSVSGNSSAAVIDVVEERSNGGDTNDPPANVSSASSG 2612
             ||.                            |||:....|.:.:.::
plant  2035 -DSH----------------------------GNSTETEADELNQNNS----------------- 2053

  Fly  2613 AGQSSTSGGPVRPVVNFDQLWDDFLQSEGLRLASRSGGGAGSGSGSVGASSSGQQNGSNTTASST 2677
                           :..|:.|              ..|.|.....|.:.|:|::..|.|.|
plant  2054 ---------------SLQQVTD--------------AAGNGQEQAQVSSQSAGERGSSQTQA--- 2086

  Fly  2678 NSGNNSGIGNLRLRTNPDVDVGSGNGSGSGSGSNAGVVNDNGISGGGGSDGASTSSDTGAPGGAR 2742
                                                                 ...|....|...
plant  2087 -----------------------------------------------------MPQDMRIEGDET 2098

  Fly  2743 DLNASLLGDVSTSESDSDP-STENDERNEEDEDEDDDAPDE-DVDEHSETDVDEERSRQFIEVFD 2805
            .|...:..|....|.:.|. .......|..|:|.|||..|| :.||..:.|.|
plant  2099 ILPEPIQMDFMREEIEGDQIEMSFHVENRADDDVDDDMGDEGEDDEGDDEDAD------------ 2151

  Fly  2806 HIYEPESSETASNDADVDNDDDDDEDDVDDDDDDDEDNDDDVREEVQSVMDAEIENRIDIALALV 2870
             :.|..:...:....||::.:|....|..:||..|||:||.....|..|...|..:.:|
plant  2152 -LVEDGAGVMSLAGTDVEDPEDTGLGDEYNDDMVDEDDDDFHENRVIEVRWREALDGLD------ 2209

  Fly  2871 SSNNRPRRSAAVNASGDGSANRTNPDDEVDDEDDDVDADPDGDPDVDPISGPSAAQAEAYLYERL 2935
                   ....:..||.|:.           ..||:.|:|....:||          :.:...|
plant  2210 -------HFQILGRSGGGNG-----------FIDDITAEPFEGVNVD----------DLFALRR- 2245

  Fly  2936 GSGLMPTPPVGFRVRMNSSIAQPLDIDVNGGNAGSGSNAGATGSSGGSGQRSSTGGTTASIGAIA 3000
                    |:||..|..:           |.::...|.:...|.......|.|..|.|||:.|.|
plant  2246 --------PLGFERRRQT-----------GRSSLDRSGSEVHGFQHPLFSRPSQTGNTASVSASA 2291

  Fly  3001 SAALRPS-SGSWMAPDFNFIRISGGDSSMGSGPAIGGNANGGDMNVFITPSMSLERAGGAPGSGQ 3064
            .:..|.| :||:....|                           .:|.||.:..::....|.|.:
plant  2292 GSISRHSEAGSYDVAQF---------------------------YMFDTPVLPFDQVPVDPFSAR 2329

  Fly  3065 TMSELLNEQPTGAGGGGGG--------GSASGVGGVGANGGTTGQHPNATLCTNGVRRRLLYLDQ 3121
            .           ||||...        |..|...|||.:..|...||..:..:..:
plant  2330 L-----------AGGGAPPPLTDYSVVGMDSSRRGVGDSRWTDIGHPQPSSLSASI--------- 2374

  Fly  3122 QYCVCMPTHQNPTEETQMETFTQDALHWWLEEATLLDMESQTDACLYAAHFLLPHLIKELKAAHQ 3186
                                                            |..:..|.|..|:|
plant  2375 ------------------------------------------------AQLIEEHFISNLRA--- 2388

  Fly  3187 QRKQEEAARQSTTPASGSNASATSSSTTSVVGTAAPTATSSIASGLLANAVSAGSGSSSLVVPPV 3251
                                             :||
plant  2389 ---------------------------------SAP----------------------------- 2391

  Fly  3252 AASATGGTRRSSIPVLISSTLGPSSASSATSATGNGATSDATTTTGGPTRNFSSVDSNVSSETQT 3316
                                                                  |::.|..||.|
plant  2392 ------------------------------------------------------VNTVVERETNT 2402

  Fly  3317 TTRPPRQRGGLRQQSQLPFNIYAEIDLTNEQDSEGDRSTSTTTGTAADGAESQSQHNSSSTAAQV 3381
            |                      ||
plant  2403 T----------------------EI---------------------------------------- 2405

  Fly  3382 AVPQHQRHPPVPLLPSSGRPSRPHTRLDETELLLLQLTDRQIRNRLQGSSGHTNSSRTSGSALIN 3446
               |.|.||.||  ||.|         .||.|                ..|:....::....|:|
plant  2406 ---QEQLHPDVP--PSVG---------SETVL----------------GDGNEGGQQSEERELLN 2440

  Fly  3447 ARPNRDLPACLQRHDHPAGSIFPRPSANRTPAPTLVSMPTPMSNAALEQLNVTAPDVVRTDRNFA 3511
            ...|.:.|.     |..|.| |.:..||      |.|..:..:..:|:||.|..|..:.:..|
plant  2441 NNENVNNPP-----DVMAES-FAQGQAN------LASPVSQDTGESLQQLEVMQPLPLNSTPN-- 2491

  Fly  3512 LPSSLEVD-VDVLPG---IVDLPQQEA---------QPEDDQL------LLPPPPPPPPSDTTPL 3557
                 |:| ::|..|   .:|....||         ||:...:      .:.||...|.|:..|.
plant  2492 -----EIDRMEVGEGDGAPIDQVDHEAVHLISTAQGQPDTSSIQNVSVTAIAPPVDDPDSNFQPS 2551

  Fly  3558 VHAEDDLWPGTVVSAGTREESSAPAVATESTEAVNESNQPEPTPESSESTSPNPQAPSAEPTPLE 3622
            |..:                     ::::..|. |:|.||.|....:...|
plant  2552 VDVD---------------------MSSDGAEG-NQSVQPSPLDGDNNELS-------------- 2580

  Fly  3623 PGAAVDASVGAQTPATTEEAASTAGASGTTATITDMSPEVRAALGDLEVPEGVDPSFLAALPSEM 3687
               :::|:...:.....||           .::...:|||.|          :||:||.|||.::
plant  2581 ---SMEATENVRNDEQVEE-----------GSLDGRAPEVNA----------IDPTFLEALPEDL 2621

  Fly  3688 REEVIQEHLRMQRIRQRAQQNAIQIAHDS-----LVEVNPEFLAALPLNIQSEVLMQQRIEQQRQ 3747
            |.||:            |.|.|..:...:     :.:::||||||||.:||:|||.|||  .||.
plant  2622 RAEVL------------ASQQAQSVQPPTYEPPPVDDIDPEFLAALPPDIQTEVLAQQR--AQRM 2672

  Fly  3748 AAQTANPEDPVDTAAFFQNLPENLRQAILTDMEESQIASLPPELAAEAQFLRRDWESRNGARMDA 3812
            ..|:......:|.|:....||.:||:.:|....|:.:|:||..|.||||.||....|...||...
plant  2673 VQQSQGQAVDMDNASIIATLPADLREEVLLTSSEAVLAALPSPLLAEAQMLRDRAMSHYQARSSV 2737

  Fly  3813 HPPSNALSRFQTTL---------QSLDDTRWHSSIWYDASGNAQPQHHQHTTIVHQHPHAHHAPN 3868
            ...|:.|:..:..|         :.:..|....::...|.|
plant  2738 FGSSHRLNNRRNGLGYNRLTGMDRGVGVTIGQRAVSSSADG------------------------ 2778

  Fly  3869 MGKPLALLMMEDE-NILLDPDSLATLLLFLFVEDQKVNSMRLHRVIRNLCHHEPTRDWIISALIS 3932
                  |.:.|.| :.|::.|:|.:|:..|.:. |.:....|.|::.|||.|..||..::..|:.
plant  2779 ------LKVKEIEGDPLVNADALKSLIRLLRLA-QPLGKGLLQRLLLNLCAHSFTRANLVQLLLD 2836

  Fly  3933 IIQKTNEDNANFGAGQAGGKPEWLKL-RVDAAFGYKSNIFLINRLYEGSARSISINPQAAQMIVR 3996
            :|:...|.:           |..|.: .....:|.:||:     :|..|.....:.|    ::.|
plant  2837 MIRPEMETS-----------PSELAITNPQRLYGCQSNV-----VYGRSQLLNGLPP----LVFR 2881

  Fly  3997 NCLDLLFVLAKHYPSSFVPFNRDVKARRILSAVFGMPSPTAGSGGGAGSGSAASGGLTGYDDVPP 4061
            ..|::|..||.::                                     ||.:..|..:|.
plant  2882 RVLEVLTYLATNH-------------------------------------SAVADMLFYFDS--- 2906

  Fly  4062 GGTLDFRSRFCRYQVVNRLRSIFDDHPAPKPSVPLDEAPSTSKAAAAKAAATAKVSTAGSQNKHS 4126
                         .::::|.|                                      .:.|..
plant  2907 -------------SLLSQLSS--------------------------------------RKGKEK 2920

  Fly  4127 VPYQTNAKNFWDVVLNIDQQTQVRLANVAQFPLTSQPAWEWQPNTADFLSFSESPFGQLLEMLPY 4191
            |.:.|::::     |.|.....::|.|..|                  |..|.|..|.::.:|..
plant  2921 VTHVTDSRD-----LEIPLVVFLKLLNRPQ------------------LLQSTSHLGLVMGLLQV 2962

  Fly  4192 KVICRSPHLTDMLVKLLASLSTELPKEEELLPLSDQMPPLVPIGPVQRAGAAAAAAHPPPPQPPA 4256
            .|...:..:...      |.|:.:|::.|..|
plant  2963 VVYTAASRIEGW------SPSSGVPEKLENKP--------------------------------- 2988

  Fly  4257 ENTATATEIGDGLAANIEEQASPASGNPASGDSNAGAKRTQLPTLSVALPVTPSKPRRKIYSKNF 4321
                            :.|:||..:...|..:....|      .||||        |||
plant  2989 ----------------VGEEASSETRKDAESELVGEA------DLSVA--------RRK------ 3017

  Fly  4322 SQLQLVIEVLTHQCGTTEGLDNVAKLIVNLTQCSQASSAIFIQY--LTAAILGLAEEVRQAIQML 4384
                        .|.      .:..:.:.|.|....:..|.:.|  |:..|..||.||
plant  3018 ------------NCA------EIYNIFLQLPQSDLCNLCILLGYEGLSDKIYSLAGEV------- 3057

  Fly  4385 LNEIRMYNIHQGGAGTTSQAASTSGAAAATASYVPTVSGASLLPNLAVHEGIMQDRFTAEHVIIS 4449
                                                      |..||..:...:..||.|...::
plant  3058 ------------------------------------------LKKLAAVDVAHRKFFTKELSELA 3080

  Fly  4450 APKNAKPTCELQLPSMKKLMSNSS---AQPYFLRTLKIFMQVRDMYEAQNGLSTGGGVACGAGDN 4511
            :..::....||...|.|:.||.|:   |....||.|::...:..
plant  3081 SSLSSSTVRELATLSSKQKMSRSTGSMAGASILRVLQVLSSLTS--------------------- 3124

  Fly  4512 DDDIIDIEGDGGASGGSSSDMAPGSASTISPPPPMETNQIAQDGDDDEEDDDEARSFPGVGNHAV 4576
                                             |::.:.:..:.:.::|:.:
plant  3125 ---------------------------------PIDESNVGTERETEQEEQN------------- 3143

  Fly  4577 ASASKSTKPTLSQIL--CLDVLWNTLSECLVALEESKDEFA----------VLVLQPT------- 4622
                      :.|.|  .|:.||:.||:|:...|...|..|          ||.:.||
plant  3144 ----------IMQRLNVALEPLWHELSQCISMTELQLDHTAAASNINPGDHVLGISPTSSLSPGT 3198

  Fly  4623 ------VEAFFLIHASHRGASKKSGRSFMPNAAGFGLRAAAGAGAIGGLGAAAPSAQEYSPFMDD 4681
                  :||||::      ..|....|.:..                .....|...:|
plant  3199 QRLLPLIEAFFVL------CEKIQTPSMLQQ----------------DTNVTAGEVKE------- 3234

  Fly  4682 VSSANTPSSASFDDEPRMQDASTNTPLVTNPSTSTAMSAHEAQLRQDRQKFLQFAEKHRTVLNQI 4746
             |||:..||.:..|..:..|.|..                          |.:||||||.:||..
plant  3235 -SSAHGSSSKTSVDSQKKTDGSVT--------------------------FSKFAEKHRRLLNSF 3272

  Fly  4747 LRQSPTHLSDGPFAVLVDHTRILDFDVKRKYFQTELERLDEGIRREEH-----TVSVRRVTVFED 4806
            :||:|: |.:...::::...|::|||.|:.||::.:..     :.::|     .:||||..|.||
plant  3273 IRQNPS-LLEKSLSMMLKAPRLIDFDNKKAYFRSRIRH-----QHDQHISGPLRISVRRAYVLED 3331

  Fly  4807 SFRVLYRLGPEEWKNRFYIVFEDEEGQDAGGLLREWYVIISREIFNPMYALFCVSPGDRVTYMIN 4871
            |:..|....|::.|.|..:.|:.|||.|||||.||||.::||.||:....|| .:.|:..|:..|
plant  3332 SYNQLRMRSPQDLKGRLNVQFQGEEGIDAGGLTREWYQLLSRVIFDKGALLF-TTVGNDATFQPN 3395

  Fly  4872 PSSHANPNHLSYFKFVGRVIAKAVHDNKLLECYFTRSFYKHILGKQVKHTDMESQDYEFYKGLDY 4936
            |:|.....||||||||||::|||:.|.:||:.||||||||||||.:|.:.|:|:.|.::||.|.:
plant  3396 PNSVYQTEHLSYFKFVGRMVAKALFDGQLLDVYFTRSFYKHILGVKVTYHDIEAVDPDYYKNLKW 3460

  Fly  4937 LMKNDISTLGYELTFSTEVQE-----FGVTQIRD--LKPNGRDTAVTEENKFEYVQLVCQLKMSG 4994
            |::||:|.: .:||||.:..|     :..|::.|  |||.||:..||||.|.|||.||....::.
plant  3461 LLENDVSDI-LDLTFSMDADEEKHILYEKTEVTDYELKPGGRNIRVTEETKHEYVDLVAGHILTN 3524

  Fly  4995 SIRQQLDAFLEGFYDIIPKHLISIFNEQELELLISGLPDIDIEDLKANTEYHKYTSKSAQIQWFW 5059
            :||.|::||||||.::||:.|:||||::||||||||||:||.:||||||||..||:.|..|.|||
plant  3525 AIRPQINAFLEGFNELIPRELVSIFNDKELELLISGLPEIDFDDLKANTEYTSYTAGSPVIHWFW 3589

  Fly  5060 RALRSFDQADRAKFLQFVTGTSKVPLQGFGSLEGMNGIQKFQIHRDDRSTDRLPCAHTCFNQLDL 5124
            ..:::|.:.|.|:|||||||||||||:||.:|:|::|.|:.|||:...:.:|||.||||||||||
plant  3590 EVVKAFSKEDMARFLQFVTGTSKVPLEGFKALQGISGPQRLQIHKAYGAPERLPSAHTCFNQLDL 3654

  Fly  5125 PMYKSYDKLRSCLLKAIHECSEGFGFA 5151
            |.|:|.::|:..||.||||.|||||||
plant  3655 PEYQSKEQLQERLLLAIHEASEGFGFA 3681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HUWE1	NP_001285288.1	DUF908	90..326	CDD:283630	68/257 (26%)
		DUF913	621..989	CDD:283642	85/368 (23%)
		UBA_like_SF	1467..1506	CDD:304366	14/41 (34%)
		WWE	1756..1828	CDD:128922	3/71 (4%)
		40S_SA_C	3575..3651	CDD:292740	10/75 (13%)
		DUF4414	3675..3779	CDD:291075	39/108 (36%)
		HECTc	4796..5149	CDD:238033	191/359 (53%)
		HECTc	4820..5148	CDD:214523	180/334 (54%)
UPL1	NP_001185245.1	DUF908	88..358	CDD:283630	77/288 (27%)
		DUF913	416..763	CDD:283642	108/565 (19%)
		UBA_atUPL1_2_like	1273..1310	CDD:270512	13/37 (35%)
		DUF4414	2609..2704	CDD:291075	39/108 (36%)
		HECTc	3319..3679	CDD:238033	191/361 (53%)
		HECTc	3343..3678	CDD:214523	180/336 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	330	1.000	Domainoid score	I261
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	879	1.000	Inparanoid score	I59
OMA	1	1.010	-	-		QHG55621
OrthoDB	1	1.010	-	-		D25515at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3148
orthoMCL	1	0.900	-	-		OOG6_101783
Panther	1	1.100	-	-	LDO	PTHR11254
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3469
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840