Sequence 1: | NP_001285288.1 | Gene: | HUWE1 / 32510 | FlyBaseID: | FBgn0030674 | Length: | 5151 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001072737.1 | Gene: | itch / 780194 | XenbaseID: | XB-GENE-976485 | Length: | 853 | Species: | Xenopus tropicalis |
Alignment Length: | 814 | Identity: | 235/814 - (28%) |
---|---|---|---|
Similarity: | 358/814 - (43%) | Gaps: | 154/814 - (18%) |
- Green bases have known domain annotations that are detailed below.
Fly 4429 NLAVHEGIMQDRFTAEHVIISAPKNAKPTCELQLPSMKKLMSNSSAQPYFLRTLKIFMQVRDMYE 4493
Fly 4494 AQNGLSTGGGVACGAGDNDDDIIDIEGDGGA---------------SGGSSSDMAPGSASTISPP 4543
Fly 4544 ----PPMETNQIAQD-----GDDDEEDDDEARSFPGVGNHAVASASKSTKPTLSQILCLDV---- 4595
Fly 4596 ---------------------------------LWNTLSECLVALEESKDEFAVLVL-------- 4619
Fly 4620 ---QPTVEA------FFLIHASHRGASKKSGRSFMPNAAGFGLRAAAGAGAIGGLGAAAPSAQEY 4675
Fly 4676 SPF----------MDD---VSSANTPSSASFDDEPRMQDASTNTPLVTNPSTSTAMSAHEAQLRQ 4727
Fly 4728 DRQKFLQFAEKHRTVLNQI-LRQSPTHLSDGPFAVLVDHTRILDFDVKRKYFQTELERLDEGIRR 4791
Fly 4792 EEHT-VSVRRVTVFEDSFRVLYRLGPEEWKNRFYIVFEDEEGQDAGGLLREWYVIISREIFNPMY 4855
Fly 4856 ALFCVSPGDRVTYMINPSSHANPNHLSYFKFVGRVIAKAVHDNKLLECYFTRSFYKHILGKQVKH 4920
Fly 4921 TDMESQDYEFYKGLDYLMKNDISTLGYELTFSTEVQEFGVTQIRDLKPNGRDTAVTEENKFEYVQ 4985
Fly 4986 LVCQLKMSGSIRQQLDAFLEGFYDIIPKHLISIFNEQELELLISGLPDIDIEDLKANTEYHKYTS 5050
Fly 5051 KSAQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFGSLEGMNGIQKFQIHRDDRSTDRLPCA 5115
Fly 5116 HTCFNQLDLPMYKSYDKLRSCLLKAIHECSEGFG 5149 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
HUWE1 | NP_001285288.1 | DUF908 | 90..326 | CDD:283630 | |
DUF913 | 621..989 | CDD:283642 | |||
UBA_like_SF | 1467..1506 | CDD:304366 | |||
WWE | 1756..1828 | CDD:128922 | |||
40S_SA_C | 3575..3651 | CDD:292740 | |||
DUF4414 | 3675..3779 | CDD:291075 | |||
HECTc | 4796..5149 | CDD:238033 | 155/352 (44%) | ||
HECTc | 4820..5148 | CDD:214523 | 146/327 (45%) | ||
itch | NP_001072737.1 | C2_E3_ubiquitin_ligase | 17..137 | CDD:175988 | 10/60 (17%) |
WW | 279..308 | CDD:306827 | 1/28 (4%) | ||
HUL4 | <310..853 | CDD:227354 | 196/580 (34%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.910 |