|
Fly 1 MKVDTVKLKKGSSELTAECRELIDELTKRRTRAELLEFLDTVHVWIYGKCELYHWIEILDRFDKI 65
||||..||||..:|..|:||.|||:|........||| |..:..|..||||||||:::|||||.|
Rat 1 MKVDRTKLKKTPTEAPADCRALIDKLKVCNDEQLLLE-LQQIKTWNIGKCELYHWVDLLDRFDGI 64
Fly 66 LEEASRHVNGNEFVLQCDTNFQETDVTLLLHVLNFTTLLIEHSFSRHLYNSIEHLTVLLSSQNMD 130
|.:|.:.|....::|.||...:|....|||.|||||.||||:|||||||:||||||.||:|.:|.
Rat 65 LADAGQTVENMSWMLVCDRPEKEQLKMLLLAVLNFTALLIEYSFSRHLYSSIEHLTTLLASSDMQ 129
Fly 131 IVLAVLNLLYMFSKRSNFIPRLPFEKKELLIVKLFNIAE------RWGDPNYGLSLKDCCIGEPK 189
:|||||||||:||||||:|.||..:|:..|:.:|.::|| .||....|..|.:||.....
Rat 130 VVLAVLNLLYVFSKRSNYITRLGSDKRTPLLTRLQHLAEFFFFTKSWGGKENGFGLAECCRDLQM 194
Fly 190 LEF---LYQLCIDYVDEHGHAAQLEIPDMMDLCH----------TASAPEVIKTIAGQISKPSEA 241
|:: ...|..::..:.|...::|.....:..| :.|..|:::::....|.|.:.
Rat 195 LKYPPSATTLHFEFYADPGAEVKIEKRTTSNTLHYIHIEQLDKISESPSEIMESLTKMYSIPKDK 259
Fly 242 IKMRIAHRVRLISGFNNYKLRLQFVQARLQAVSILIYSNALQDNTDKVLYAGFGEELCELIDKED 306
..:...| :||..||:|::.|||.|||||.|:|||:||||||::.:.:||.|..|||.:::...|
Rat 260 QMLLFTH-IRLAHGFSNHRKRLQAVQARLHAISILVYSNALQESANSILYNGLIEELVDVLQITD 323
Fly 307 VHLVEIRAAVLRTLTSMLHFDRNPNVPRAGSRLMKIVHYTGAERQGGTLPLLVRDCIDNLTTHGL 371
..|:||:||.||||||::|.:|.| :|..|:..||.....|.||:|||:||..:....:
Rat 324 KQLMEIKAASLRTLTSIVHLERTP-------KLSSIIDCTGTASYHGFLPVLVRNCIQAMIDPSM 381
Fly 372 TERYPLILATSLFSLLYHLASYEMGGTALVKSGMMQSLLCVISWPGVDLEHITFVTRAVRVIDLI 436
:.||...||:|||.|||||||:.||.|||..|||::||.||.:.|.:.:.||||||||||:|||
Rat 382 -DPYPHQFATALFSFLYHLASYDAGGEALVSCGMMEALLKVIKFLGDEQDQITFVTRAVRVVDLI 445
Fly 437 TNIDIARFHQNNGLNVFIDRLEKEIKSCCKALADIGITLK-----ESTLRDDHKLDTSLDHVDED 496
||:|:|.|..::||::||.|||.|:..|.| :....:| .||.::..:::|.:|..|..
Rat 446 TNLDMAAFQSHSGLSIFIYRLEHEVDLCRK---ECPFVIKPKIQRPSTTQEGEEMETDMDVADVT 507
Fly 497 VEDGSGENASVTSGNASPRRDNSSDGATGAGSIVYRAYHEHIGGAGSGAGLLDIGGARSSLSGGS 561
:|...|.:.|:........|.:||:.:|. |.|.|.|.| .|.......|.
Rat 508 MESSPGSSISMEHRLDVELRASSSNSSTS------------ISGPGPGPG----PGPGPGPGPGP 556
Fly 562 SGTSGMGAGSINRDGSAARPPAIMYPTNSYYARPLAERKAELSSQLPSSLAPKKPSCVTQRAALL 626
....|.|.|.....|....| ||..: |:.||||||
Rat 557 GPGPGPGLGPSLGPGPGPGP------------RPGVQ-------------------CIPQRAALL 590
Fly 627 KSMLNFLKKSIQDHAHFSNMRNIMETSLTQSLRHIIANAEYYGPSLFLLATDVVTVYVFNEPSLL 691
|||||||||:|||.|....:|::|:.||..||:|||:||||||||||||||:||||:||.|||||
Rat 591 KSMLNFLKKAIQDPAFSDGIRHVMDGSLPTSLKHIISNAEYYGPSLFLLATEVVTVFVFQEPSLL 655
Fly 692 SSLQDLGITSVMLKALLQKDVPATREVLGSLPNVFSALCLNERGLFEFLSYDPFDKVLKVLLSPD 756
|||||.|:|.|||.|||.|||||||||||||||||||||||.|||..|:...||:::.|||||||
Rat 656 SSLQDNGLTDVMLHALLIKDVPATREVLGSLPNVFSALCLNARGLQSFVQCQPFERLFKVLLSPD 720
Fly 757 YLVAMRRRRSSDPLGDTATNLGNAMDDLIKHHPYLRADATEAIVRLLNELVRLGSDPSFICWRAN 821
||.|||||||||||||||:|||:|:|:|::|.|.|:.|||.||::||.|:..||.||.:|| .
Rat 721 YLPAMRRRRSSDPLGDTASNLGSAVDELMRHQPTLKTDATTAIIKLLEEICNLGRDPKYIC---Q 782
Fly 822 KESSGSGSGSGSHGGGHHVASTPSPMVMVAGTGSASSVLQGAADTNDSSGDDDDDDDEMSSASQQ 886
|.|.....|: .|.|.|. ...||:...|..:::::...|.|.:..
Rat 783 KPSIQKADGT---------TSAPPPR------------SNHAAEEASSEDEEEEEVQAMQSFNSA 826
Fly 887 QQQPTTPGQGGGPSTPRTQQAGGVVGSGAGATGTPAAASQAVKVVTPPEREAIPLIDYILNVMKF 951
||..|.|.| :||...||..|||:|||||||||
Rat 827 QQNETEPNQ---------------------------------QVVGTEERIPIPLMDYILNVMKF 858
Fly 952 IEAIFSNSPNGDHCREFVLHGGLKPILQLLSLPNLPVDSPVSTTSQAVANVCKAILSQAQETKVL 1016
:|:|.||:...|||:|||...||.|::.:|.|||||:|.|.|...||||.|||:||:.:.|.|||
Rat 859 VESILSNNTTDDHCQEFVNQKGLLPLVTILGLPNLPIDFPTSAACQAVAGVCKSILTLSHEPKVL 923
Fly 1017 DVALKQLADIVAQLKPLIKHFTFPGGSVLLAELVCCQRLEDGFANAEYTPILHNMSFVHGYVVML 1081
...|.||..|::.|:||.:....|||||||.||.|...:.|...:|:.||:||.::..|.|::|.
Rat 924 QEGLLQLDLILSSLEPLHRPIESPGGSVLLRELACAGNVADATLSAQATPLLHALTAAHAYIMMF 988
Fly 1082 VHLCRNASNDMRTILLKRWGVNRETGVQLLQQLVQLYISLVWESTILLNLCS------------- 1133
||.||...:::|:|.:.:|| .:.|:.:|.:|.|||.|||||||:||:||:
Rat 989 VHTCRVGQSEIRSISVNQWG--SQLGLSVLSKLSQLYCSLVWESTVLLSLCTPNSLPSGCEFGQA 1051
Fly 1134 --------DEPT------QHPDLIWDEIAAQMSAAAG--------TADPLTEAELSRKLERAAEF 1176
||.. :..|...|..|..|.|:|. ..|.|...|........::.
Rat 1052 DMQKLVPKDEKAGTTQGGKRSDGEQDGTAGSMDASAQGLLEGIELDGDTLAPMETDEPSSSDSKG 1116
Fly 1177 RTKYTP--EEQFRYIKSLLAASSRLGRALAELLGTLVKLSVGSPQTRQRRINDLISNITKVPTPE 1239
::|.|| ..:.:.||.||:||||||||||||.|.||||.|||| .||||.:...|. |..|||.
Rat 1117 KSKITPAMAARIKQIKPLLSASSRLGRALAELFGLLVKLCVGSP-VRQRRSHHAAST-TTAPTPA 1179
Fly 1240 AREIARILSSILVNGFSHESILPKPVPKLKLTFLICSVGFTGPMLFDDKRSAFHLMISQFCAENG 1304
||..|..|:.:|..|.|.:.....|.|:.:|||.|||||||.|||||:::..:|||:.:|....|
Rat 1180 ARSTASALTKLLTKGLSWQPPPYTPTPRFRLTFFICSVGFTSPMLFDERKYPYHLMLQKFLCSGG 1244
Fly 1305 LKAFFEMFYWALSLDN---VSQKFEFDQWASMEDLMQSHEDDKRDCPEGTGEFLDAWLQLLEKMV 1366
..|.||.|.||||:.. ||:..|.. |.|:||||||||||.|:||||
Rat 1245 HNALFETFNWALSMGGKVPVSEGLEHS-----------------DLPDGTGEFLDAWLMLVEKMV 1292
Fly 1367 NPRAMLDSPYTMSPRLNYMPDSVP-FEPVFYLIHIHQLAMQALRRIWARRPIPNYGPSMFETMIL 1430
||..:|:||:::..:|.....|.| |..:.:|:...:.|...::.:|.|:|:..||..|.|:|:.
Rat 1293 NPTTVLESPHSLPAKLPGGVQSFPQFSALRFLVVTQKAAFTCIKNLWNRKPLKVYGGRMAESMLA 1357
Fly 1431 ILKHLIKSHQTLLDRYHTRMKEIKFENLYIRSTDDG-------LNADHIKTLTDMGFMHYHVIEA 1488
||.|:::....:.:|.....:..:.|. ....::| :|...::.|.||||...|.:||
Rat 1358 ILCHILRGEPVIRERLSKEKEGSRGEE--EAGQEEGGSRREPQVNQQQLQQLMDMGFTREHAMEA 1420
Fly 1489 LRTNASLEEATDYLLNNPEASSLSTTGG-QSSSSAPPPPPPPSASTMDIDVDVPAD--GESTQ-- 1548
|...:::|:||:|||.:|. ...|| ....|.........|..|.:..|:|.| .||.:
Rat 1421 LLNTSTMEQATEYLLTHPP----PIIGGVVRDLSMSEEDQMMRAIAMSLGQDIPMDQRAESPEEV 1481
Fly 1549 ----SKSSTSPNSSYDYKHLKLMPSL---------IFDRFCDEAISRAFEFMEAIPDTVNSAADL 1600
.:.........:.:..|.:... ....|.|..:...|..::.:||||....||
Rat 1482 ACRKEEEERKAREKQEEEEAKCLEKFQDADPLEQDELHTFTDTMLPGCFHLLDELPDTVYRVCDL 1546
Fly 1601 IAVLYRRHNHLNKQVFVTNFVRNIIQWVDFTLQLFEPAKTTGSKASRLEECLTGMT----ATRLF 1661
|....:|:....:.:.:...|..:.:..|..::...|..|:.:|. :.|.::.|. |:.|.
Rat 1547 IMTAIKRNGADYRDMILKQVVNQVWEAADVLIKAALPLTTSDTKT--VSEWISQMATLPQASNLA 1609
Fly 1662 VRLKTSTLLLEENYSDLHRPLVEAITAQDAMVSLVKLLDCMSQWMLEQSTETNTGQQRATVPRWV 1726
.|:...|||.|| |..|....:.:...:..|:|||:.: |..|:.:.| |:....|:|:
Rat 1610 TRILLLTLLFEE----LKLPCAWVVESSGILNVLIKLLEVV-QPCLQAAKE----QKEVQTPKWI 1665
Fly 1727 QNLVDLIDAIDSISHILQRKANMRAV---SSDVWRWYDASTGKWNAYSEANNELIRNAYAAGERW 1788
..::.|||..:..:...:|:|.|... :|:.|||:|..:|:|.:||.:||..|.:|:.:||..
Rat 1666 TPVLLLIDFYEKTAISSKRRAQMTKYLQSNSNNWRWFDDRSGRWCSYSASNNSTIDSAWKSGETS 1730
Fly 1789 LYINIGRQRCTVSLNCMTQVSEASGTHRPVCPALKLSEAITSLNNPVALHKVEHILNRVVRTAPD 1853
:....||:|.||....|.||:|.:|..||| .:|.|..| |:.:.:..
Rat 1731 VRFTAGRRRYTVQFTTMVQVNEETGNRRPV--------MLTLLRVP-----------RLSKNSKS 1776
Fly 1854 GSGTVHSDELISLRQLVNFTDGQQPQQSENSANPSEEATSEDGPAAANSGSPPATMTTRSKTRQK 1918
.:| .||....:....|| .::.||..| |.|.|..| |.|.:..:.::
Rat 1777 SNG----QELEKTLEESKETD---IKRKENKGN--------DIPLALES-----TNTEKDASLEE 1821
Fly 1919 SAAAAAAAKNKSQSGGSPPIPKRTQKIILNEEQVGLSKFDCGRIIGSIVDLLQPSHQMLNETKLS 1983
:.......:. |.|:.|.:....|..::|..|| .:|..:
Rat 1822 TKIGEILIQG------------------LTEDMVTVLIRACVSMLGVPVD---------PDTLHA 1859
Fly 1984 LLRLCARLTRNYDNAQVFIRRGGVRMLLHLQQACSFMGFPTYANIILRHVLEAPPVLQEAMERVL 2048
.||||.||||::..|.:|......||:|:|.|:..|.||.....::|||::|.|..|:..||:|:
Rat 1860 TLRLCLRLTRDHKYAMMFAELKSTRMILNLTQSSGFNGFTPLVTLLLRHIIEDPCTLRHTMEKVV 1924
Fly 2049 --------GMRAAGIV--PVGHRDLIYVLTQVSSAVSRNPQIFVAAAKEMLKGEYLINTNSTTLA 2103
|...:|:| .:|.|::.|:|..:..|..|||.||...|...::........|.|.:
Rat 1925 RSAATSGAGSTTSGVVSGSLGSREINYILRVLGPAACRNPDIFTEVANCCIRIALPAPRGSGTAS 1989
Fly 2104 DDARVMVKSKFGQQPTAAAGGATPHNQTPTPPPAAKDELKDDPQVQSSVAV----LKELLHGLVQ 2164
||....::.| .|.|...:|..|...||:.| :||:::.::.
Rat 1990 DDEFENLRIK---------------------GPNAVQLVKTTPLKPSSLPVIPDTIKEVIYDMLN 2033
Fly 2165 PCWHYGGTGSLDRG--------QGAAELLQ---------------PDQPPGTAQGCHDDELYFRF 2206
....|......|:. |...:||| ......|..|...:...|..
Rat 2034 ALAAYHAPEEADKSDPKPGGMTQEVGQLLQDMGDDVYQQYRSLTRQSSDFDTQSGFSLNSQVFAA 2098
Fly 2207 QETPAPVSSKKQSSSGGGAAAAGQTGQATEKFEPCCCTWHIPTSGHTHAKPTISRATLLKLLADS 2271
...||..|: ..:|.|.||:...:|.:..:..|....:......| ..:||.:..:|:|:|||:.
Rat 2099 DGAPAETST-TGTSQGEGASTPEETREGKKDKEGDRTSEEGKQKG-KGSKPLMPTSTILRLLAEL 2161
Fly 2272 TRAYQSLVPRVLLSHVYTPADSPLISAPQQTFLGVLLDRFLPITQRHHVPEVSTMTRVLICSLSD 2336
.|:|.. :..::.::.||...|.||. ...:.|..:||..||.||.....:...:.|:.:.||:.
Rat 2162 VRSYVG-IATLIANYSYTVGQSELIK-EDCSVLAFVLDHLLPHTQNAEDKDTPALARLFLASLAA 2224
Fly 2337 CYQQPGVQVHVAEELHAAVARALAQPDSAEKHTRLQVLMSLFPNLIES----PMLYDKV-----H 2392
.......||.:..|:.||:.||||..:|.|||.|||.:|.:...::|| ...|... |
Rat 2225 AGSGTDAQVALVNEVKAALGRALAMAESTEKHARLQAVMCIISTIMESCPSTSSFYSSATAKTQH 2289
Fly 2393 MHRNNMYRVLLRQGVMTYLTKVAQYKDLSNHNTLSTLAAILRPMEILLRFSVSTTTLGSKRILFG 2457
...||:.|:.|::|::..|.:|....|||:.|..:|:.|.|:|:|.|.|. :.....|||
Rat 2290 NGMNNIIRLFLKKGLVNDLARVPHSLDLSSPNMANTVNAALKPLETLSRI------VNQPSSLFG 2348
Fly 2458 SGGPGGPNASGNGNNTAGGSSGNGPGSGNTYGTIINRRLYPRLAARTGFGSAMERSNAMGGEHVL 2522
| ::....:....:|.|.
Rat 2349 S--------------------------------------------KSASSKSKSEQDAQGA---- 2365
Fly 2523 RDIIRNVLSDRRHAFEFIFNSDDMAVDSEDAAAPGSGVGGGGSGAGSVGGGVSGSVSGNSSAAVI 2587
|.|.:...:|...|| ...|.....
Rat 2366 --------------------SQDSSSHQQDPGEPG-----------------EAEVQEEDH---- 2389
Fly 2588 DVVEERSNGGDTNDPPANVSSASSGAGQSSTSGGPVRPVVN-FDQLWDDFLQSEGLRLASRSGGG 2651
||.:.....||..|..|...|... |||..........|.| .:.|.|:.|:.:|
Rat 2390 DVTQTEVADGDIMDGEAETDSVVI-AGQPEVLSSQEMQVENELEDLIDELLERDG---------- 2443
Fly 2652 AGSGSGSVGASSSGQQNGSNTTASSTNSGNNSGIGNLRLRTNPDVDVGSGNGSGSGSGSNAGVVN 2716
|||:.::..|.||:.. |...|:.
Rat 2444 -GSGNSTIIVSRSGEDE-----------------------------------------SQEDVLM 2466
Fly 2717 DNGISGGGGSDGASTSSDTGAPGGARDLNASLLGDVSTSESDS----DPSTENDERNEEDEDEDD 2777
|. ||. |.|....:..:..|| ||..|.:...|||....:
Rat 2467 DE------------------APS-----NLSQASTLQANREDSMNILDPEDEEEHTQEEDSSGSN 2508
Fly 2778 DAPDEDVDEHSETDVDEERSRQFIEVFDHIYEPESSETASNDADVDNDDDDDEDDVDDDDDDDED 2842
:..|:..||..|.:.||| :|.:|||.:..|:||||:.
Rat 2509 EDEDDSQDEEEEEEEDEE----------------------------DDQEDDEGEEGDEDDDDDG 2545
Fly 2843 NDDDVREEVQSVMDAEIENRIDIALALVSSNNRPRRSAAVNASGDGSANRTNPDDEVDDEDDDVD 2907
::.::.|:... :|||......|.:.:|::..|.|::.
Rat 2546 SEMELDEDYPD----------------------------MNASPLVRFERFDREDDLIIEFDNMF 2582
Fly 2908 ADPDGDPDVDPISGPSAAQAEAYLYERLGSGLMPTPPVGFRVRMNSSIAQPLDIDVNGGNAGSGS 2972
:.. .|:.|..| .:..|.|:..|...:||: ..|||
Rat 2583 SSA---TDIPPSPG----------------NIPTTHPLMVRHADHSSL-----------TLGSG- 2616
Fly 2973 NAGATGSSGGSGQRSSTGGTTASIGAIASAALRPSSGSWMAPDFNFIRISGGDSSMGSGPAIGGN 3037
|||...|..||. :...||..:.: :|..|..:
Rat 2617 --------------SSTTRLTQGIGR-SQRTLRQLTAN-------------------TGHTIHVH 2647
Fly 3038 ANGGDMNVFITPSMSLERAGGAPGSGQTMSELLNEQPTGAGGGGGGGSASGVGGVGANGGTTGQH 3102
..| |....|.:.|:|..| |.:...:.:|.:..|..:.|
Rat 2648 YPG---NRQPNPPLILQRLLG-PSAAADILQLSSSLPLQSRG----------------------- 2685
Fly 3103 PNATLCTNGVRRRLL---------------YLDQQYCVCMPTHQNPTEETQMETFTQ--DALHWW 3150
|.||| .||..: |...|..:|..|.:. .||..|
Rat 2686 ----------RARLLVGNDDVHIIARSDDELLDDFF------HDQSTATSQAGTLSSIPTALTRW 2734
Fly 3151 LEEATLLDMESQTDACLYAAHFLLPHL----IKELKAAHQQRKQEEAARQSTTPASGS------- 3204
.||..:||.||..|........::.|| .:||:...::|:::.|..::.....|.
Rat 2735 TEECKVLDAESMHDCVSVVKVPIVNHLEFLRDEELEERREKRRKQLAEEETKIIDKGKEDKENRD 2799
Fly 3205 -----NASATSSSTTSVVGTAAPTATSSIASGLLANAVSAGSGSSSLVVPPVAASATGGTRRSSI 3264
..|.|:.||...|....| :| .|.
Rat 2800 QSAQCTVSKTNDSTEQNVSDGTP-------------------------MP------------DSY 2827
Fly 3265 PVLISSTLGPSSASSATSATGNGATSDATTTTGGPTRNFSSVDSNVSSETQTTTRPPRQRGGLRQ 3329
|...|||..|:|.|..|..|.. .|:.|.|..||...|.:.|
Rat 2828 PTTPSSTDAPTSESKETLGTLQ------------------------PSQQQPTLPPPPSLGEISQ 2868
Fly 3330 QSQLPFNIYAEIDLTNEQDSEGDRSTSTTTGTAADGAESQSQHNSSSTAAQVAVPQHQRHPPVPL 3394
:.|.| ::...:|| |:.:|..
Rat 2869 ELQSP-----------------------------------AEEVGNST--QLLMPIE-------- 2888
Fly 3395 LPSSGRPSRPHTRLDETELLLLQLTDRQIRNRLQGSSGHTNSSRTSGSALINARPNRDLPACLQR 3459
|...| |:||....:.|::.|
Rat 2889 LEELG-PTRPSGEAETTQMEL-------------------------------------------- 2908
Fly 3460 HDHPAGSIFPRPSANRTPAPTLVSMPTPMSNAALEQLNVTAPDVVRTDRNFALPSSLEVDVDVLP 3524
:||||:.|:. |...| |.|.|.
Rat 2909 ----------------SPAPTITSLS---------------------------PERAE-DSDALT 2929
Fly 3525 GIVDLPQQEAQPEDDQLLLPPPPPPPPSDTTPLVHAEDDLWPGTVVSAGTREESSAPAVATESTE 3589
.: .:|.|.. |.||:.|.....:...|...:||:.|:.:|.:.......
Rat 2930 AV------SSQLEGS-----------PMDTSSLASCTLEEAVGDTPAAGSSEQPTAGSSTPGDAP 2977
Fly 3590 AVNESNQPEPTPESSESTSPNPQAPSAEPTPLEPGAAVDASV---GAQTPATTEEAASTAGASGT 3651
:|....|..| ..|.|||.| |: .|:.|...|..:..|::| ||.:....||
Rat 2978 SVGADVQGRP-DVSRESTQP-PE-DSSPPASSESSSTRDSAVAISGADSRGILEE---------- 3029
Fly 3652 TATITDMSPEVRAALGDLEVPEGVDPSFLAALPSEMREEVIQEHLRMQRIRQRA----QQNAIQI 3712
.:...|.|....|..:.:|||||||||||||.::|.||:|..|.::...:.| ......:
Rat 3030 --PLPSTSSEEEDPLAGISLPEGVDPSFLAALPDDIRREVLQNQLGIRPPTRTAPSTNSSTPAVV 3092
Fly 3713 AHDSLVEVNPEFLAALPLNIQSEVLMQQRIEQQ-RQAAQTANPEDPVDTAAFFQNLPENLRQAIL 3776
.:..:.||:||||||||..||.|||.|||.||| |:.||.|:.:.|:|...|.|.||.:||:::|
Rat 3093 GNPGVTEVSPEFLAALPPAIQEEVLAQQRAEQQRRELAQNASSDTPMDPVTFIQTLPSDLRRSVL 3157
Fly 3777 TDMEESQIASLPPELAAEAQFLRRDWESRN----GARMDAHPPSNALSRFQTTLQSLDDTRWHSS 3837
.|||:|.:|.:||::|||||.|||:.|:|. ..|:..|..::|||.. |....:.|.
Rat 3158 EDMEDSVLAVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI------LRSPAFTSR 3216
Fly 3838 IWYDASGNAQPQHHQHTTIVHQH--------PHAHHAPNMGKPLALLMMEDENILLDPDSLATLL 3894
: ||| :..|:|.:..|. ..:|:.|: |..:..|:.....:|||.::|:.||
Rat 3217 L----SGN---RGVQYTRLAVQRGGTFQMGGSSSHNRPS-GSNVDTLLRLRGRLLLDHEALSCLL 3273
Fly 3895 LFLFVEDQKVNSMRLHRVIRNLCHHEPTRDWIISALISIIQKTNE-----DNANFGAGQAGGKP- 3953
:.|||::.|:|:.|||||:||||:|..||.|:|.:|:||:|:::| :.......:..||.
Rat 3274 VLLFVDEPKLNTSRLHRVLRNLCYHAQTRHWVIRSLLSILQRSSESELCIETPKLSTSEERGKKS 3338
Fly 3954 ----------------------------EWLKLRVDAAFGYKSNIFLINR--------LYEGSAR 3982
.||.:.:|||.|.::|||.|.| .:..|..
Rat 3339 SKSCASSSHENRPLDLLHKMESKSSNQLSWLSVSMDAALGCRTNIFQIQRSGGRKHTEKHASSGS 3403
Fly 3983 SISINPQAAQMIVRNCLDLLFVLAKHYPSSFVPFNRDVKARRILSAVFGMPSPTAGSGGGAGSGS 4047
::.|:||||.::.|:.||.|..|||.:||.|. .:..| .....|....||..
Rat 3404 TVHIHPQAAPVVCRHVLDTLIQLAKVFPSHFT--QQRTK------------ETNCESDRERGSKQ 3454
Fly 4048 AASGGLTGYDDVPPGGTLDFRSRFCRYQVVNRLRSIFDDHPAPKPSVPLDEAPSTSKAAAAKAAA 4112
|.| |.:|:::::....
Rat 3455 ACS-------------------------------------------------PCSSQSSSSGICT 3470
Fly 4113 TAKVSTAGSQNKHSVPYQTNAKNFWDVVLNIDQQTQVRLA--NVAQFPLTSQPAWEWQPNTADFL 4175
:|||:::.:|.....|.. :|...|:::....| ....
Rat 3471 ----------------------DFWDLLVKLDNMNVSRKGKNSVKSVPVSAGGEGE-----TSLH 3508
Fly 4176 SFSESPFGQLLEMLPYKVICRSPHLTDMLVKLLASLSTELPKEEELLPLSDQMPPLVPIGPVQ-- 4238
|...||.|||:.||.:.||.||..||:.|::||:.:|..||:.: :..||
Rat 3509 SLEASPLGQLMNMLSHPVIRRSSLLTEKLLRLLSLISIALPENK--------------VSEVQTN 3559
Fly 4239 --RAGAAAAA------------AHPPPPQPPAENTATATEIGDGLAANIEEQASPASGNPASGDS 4289
.:|::.|| |..|.|.|||..| |.:..||...:
Rat 3560 SSNSGSSTAATSNTSTTTTTTTATAPTPTPPAATT-------------------PVTSAPALVAA 3605
Fly 4290 NAGAKRTQLPTLSVALPVT---------------PSKPRR--------KIYSKNF--SQLQLVIE 4329
.|.:..|...:.:|..|.| |:|... |:.|... :||||.:|
Rat 3606 TAISTITVAASTTVTTPTTATTTVSTSTTKGNKSPAKVGEGGSSSVDFKMVSSGLTENQLQLSVE 3670
Fly 4330 VLT-HQCGTTEGLDNVAKLIVNLTQCSQASSAIFIQYLTAAILGLAEEVRQAIQMLLNEIRMYNI 4393
||| |.| :.|||::.|.:::.|::....:....::.|......|...:.:.|..||.|:|.||:
Rat 3671 VLTSHSC-SEEGLEDAANVLLQLSRGDSGTRDTVLKLLLNGARHLGYTLCKQIGTLLAELREYNL 3734
Fly 4394 HQGGAGTTSQAASTSGAAAATASYVPTVSGASL---LPNLAVHEGIMQDRF-TAEHVIISAPKNA 4454
.| ...:...|:|...| .|.....:|.||.|| .||:|:|.|.:.
Rat 3735 EQ-----------------QRRAQCETLSPDGLPEEQPQTTKLKGKMQSRFDMAENVVIVASQK- 3781
Fly 4455 KPT--CELQLPSMKKLMSNSSAQPYFLRTLKIFMQVRDMYEAQN------------GLSTGGGVA 4505
:|. .|||||||..|.|.:|.|.:|||.|::.:|:||.....| ||.:...:.
Rat 3782 RPLGGRELQLPSMSMLTSKTSTQKFFLRVLQVIIQLRDDTRRANKKAKQTGRLGSSGLGSASSIQ 3846
Fly 4506 CGAGDND---DDIIDIEGDG-------GASGGSSSDMAPGSA-------STISPPPPMETNQ--I 4551
......: |.||.:..:| .|:...||:.:..|. ....|.|..:..| :
Rat 3847 AAVRQLEAEADAIIQMVREGQRARRQQQAATSESSNQSETSVRREESPMDVDQPSPSAQDTQSIV 3911
Fly 4552 AQDGDDDEEDDDEARSFPGVGNHAVASASKSTKPTLSQILCLDVLWNTLSECLVALEESKDEFAV 4616
..||....|.:.|.|. |.: |.||:.|.||.||:.|.|||..||||.|:.||
Rat 3912 VSDGTPQGEKEKEERP-PEL-------------PLLSEQLSLDELWDMLGECLKELEESHDQHAV 3962
Fly 4617 LVLQPTVEAFFLIHASHRGASKKSGRSFMPNAAGFGLRAAAGAGAIGGLGAAAPSAQEYSPFMDD 4681
|||||.||||||:||:.| .||...|....: ..|....|..|....
Rat 3963 LVLQPAVEAFFLVHATER-ESKPPVRDTRES-------------------QLAHIKDEPPPLSPA 4007
Fly 4682 VSSANTPSSAS--FDDEPRMQDASTNTPLVTNPSTSTAMSAHEAQLRQDRQKFLQFAEKHRTVLN 4744
..:..||||.. |..||.....|::.| .|.||||:|||.||||||
Rat 4008 PLTPATPSSLDPFFSREPSSMHISSSLP-------------------PDTQKFLRFAETHRTVLN 4053
Fly 4745 QILRQSPTHLSDGPFAVLVDHTRILDFDVKRKYFQTELERLDEGIRREEHTVSVRRVTVFEDSFR 4809
||||||.|||:|||||||||:.|:||||||||||:.||||||||:|:|:..|.|||..|||||:|
Rat 4054 QILRQSTTHLADGPFAVLVDYIRVLDFDVKRKYFRQELERLDEGLRKEDMAVHVRRDHVFEDSYR 4118
Fly 4810 VLYRLGPEEWKNRFYIVFEDEEGQDAGGLLREWYVIISREIFNPMYALFCVSPGDRVTYMINPSS 4874
.|:|..|||.|||.|||||.||||||||||||||:|||||:||||||||..||||||||.|||||
Rat 4119 ELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALFRTSPGDRVTYTINPSS 4183
Fly 4875 HANPNHLSYFKFVGRVIAKAVHDNKLLECYFTRSFYKHILGKQVKHTDMESQDYEFYKGLDYLMK 4939
|.|||||||||||||::||||:||:|||||||||||||||||.|::|||||:||.||:||.||::
Rat 4184 HCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLE 4248
Fly 4940 NDISTLGYELTFSTEVQEFGVTQIRDLKPNGRDTAVTEENKFEYVQLVCQLKMSGSIRQQLDAFL 5004
||:|||||:||||||||||||.::|||||||.:..||||||.|||.||||::|:|:||:||.|||
Rat 4249 NDVSTLGYDLTFSTEVQEFGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFL 4313
Fly 5005 EGFYDIIPKHLISIFNEQELELLISGLPDIDIEDLKANTEYHKYTSKSAQIQWFWRALRSFDQAD 5069
||||:||||.|||||.||||||||||||.|||:|||:|||||||.|.|.||||||||||||||||
Rat 4314 EGFYEIIPKRLISIFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQAD 4378
Fly 5070 RAKFLQFVTGTSKVPLQGFGSLEGMNGIQKFQIHRDDRSTDRLPCAHTCFNQLDLPMYKSYDKLR 5134
|||||||||||||||||||.:|||||||||||||||||||||||.|||||||||||.|:|::|||
Rat 4379 RAKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLR 4443
Fly 5135 SCLLKAIHECSEGFGFA 5151
..||.||.|||||||.|
Rat 4444 HMLLLAIQECSEGFGLA 4460
| 
