DRSC/TRiP Functional Genomics Resources

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Protein Alignment HUWE1 and Wwtr1

DIOPT Version :9

Sequence 1:NP_001285288.1 Gene:HUWE1 / 32510 FlyBaseID:FBgn0030674 Length:5151 Species:Drosophila melanogaster
Sequence 2:NP_001020040.1 Gene:Wwtr1 / 295062 RGDID:1559609 Length:395 Species:Rattus norvegicus


Alignment Length:410 Identity:83/410 - (20%)
Similarity:127/410 - (30%) Gaps:117/410 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly  3262 SSIPVLISSTLGPSSASSATSA----------TGNGATSDATTTTGG-PTRNFSSVDSNVSSETQ 3315
            :.:..|.:|.:.|..:|.....          :|:.:...:|.::|| |....:....:|.|.:.
  Rat    26 TDLEALFNSVMNPKPSSWRKKILPESFFKEPDSGSHSRQSSTDSSGGHPGPRLAGGAQHVRSHSS 90

  Fly  3316 TTT-----------RPPRQRGGLRQQSQLPFNIYAEIDLTNEQDSEGDRSTSTTTG--------- 3360
            ..:           .|.:|...|||||   :::..|:.|     ..|...|.|.||         
  Rat    91 PASLQLGTGAGAAGGPAQQHAHLRQQS---YDVTDELPL-----PPGWEMTFTATGQRYFLNHIE 147

  Fly  3361 ---TAADGAESQSQ---H-NSSSTAAQVAVP---------------QHQRHPPVPLLPSSGRPSR 3403
               |..|..:..:|   | |...|....:||               |||:.....|.|.:.....
  Rat   148 KITTWQDPRKVMNQPLNHVNLHPTITSTSVPQRSMAVSQPNLAMNHQHQQVVATSLSPQNHPAQN 212

  Fly  3404 PHTRLDETELLLLQLTDRQIRNRLQGSSGHTNSSRTSGSALINARPNRDLPACLQRHDHPAGSIF 3468
            |.|.|......|.....:|.:.|||.........|.....|:    .::...|.|          
  Rat   213 PPTGLMSVPNALTTQQQQQQKLRLQRIQMERERIRMRQEELM----RQEAALCRQ---------- 263

  Fly  3469 PRPSANRTPAPTLVSMPTPMSNAALEQLNVTAPDVV-----------RTDRNFALPSSLEVDVDV 3522
             .|....|.||    :.||..|..:..:..::.|..           .||....|          
  Rat   264 -LPMETETMAP----VNTPAMNTDMRSVTNSSSDPFLNGGPYHSREQSTDSGLGL---------- 313

  Fly  3523 LPGIVDLPQQEAQPEDDQLLLPPPPPPPPSDTTPL-VHAED-------DLWPGTVVSAGTREESS 3579
              |...:|   ..|||....:........|..||: |:.:.       |..|||.|..||.|...
  Rat   314 --GCYSVP---TTPEDFLSNMDEMDTGENSGQTPMTVNPQQTRFPDFLDCLPGTNVDLGTLESED 373

  Fly  3580 APAVATESTEAVNESNQPEP 3599
            ...:..:...|:|:|   ||
  Rat   374 LIPLFNDVESALNKS---EP 390

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HUWE1NP_001285288.1 DUF908 90..326 CDD:283630
DUF913 621..989 CDD:283642
UBA_like_SF 1467..1506 CDD:304366
WWE 1756..1828 CDD:128922
40S_SA_C 3575..3651 CDD:292740 6/25 (24%)
DUF4414 3675..3779 CDD:291075
HECTc 4796..5149 CDD:238033
HECTc 4820..5148 CDD:214523
Wwtr1NP_001020040.1 WW 125..156 CDD:197736 8/35 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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