| Sequence 1: | NP_001285288.1 | Gene: | HUWE1 / 32510 | FlyBaseID: | FBgn0030674 | Length: | 5151 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001257383.1 | Gene: | WWP2 / 11060 | HGNCID: | 16804 | Length: | 870 | Species: | Homo sapiens |
| Alignment Length: | 993 | Identity: | 269/993 - (27%) |
|---|---|---|---|
| Similarity: | 409/993 - (41%) | Gaps: | 255/993 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 4285 ASGDSNAGAKRTQLPTLSVALPVTPSKPRRKIYSKNFSQLQLVIEVLTHQCGTTEGLDNVAKLIV 4349
Fly 4350 NLTQCSQASSAIFIQYLTAAILGLAEEVRQ------AIQMLLNEIRMYNIHQGGAGTTSQA---- 4404
Fly 4405 ---------ASTSGAAAATASYVPTVSGASLLPNLAVHEGIMQDRFTAEHVIISAPKNAKPTCEL 4460
Fly 4461 QLPSMKKLMSNSSAQPYFLRTLKIFMQ--VRDMYEAQNGLSTGGGVACGAGDNDDDIIDIEGD-- 4521
Fly 4522 -------GGAS-----GGSSS-------DMAPGSASTISPPPPMETNQIAQDGDDDEE----DDD 4563
Fly 4564 EARSFPGVGNHAVASASKSTKPTLSQILCLDVLWNTLSECLVALEESKDEFAVLVLQPTVEAFFL 4628
Fly 4629 IHASHRGASKKSGRSFMPNAAGFGLRAAAGAGAIGGLGAAAPSAQEYSPFMDDVSSANT-----P 4688
Fly 4689 SSASFDDEPRMQ----DASTNTPLVTNPS-------------------------------TSTAM 4718
Fly 4719 SAHEA--------QLRQDRQKFLQFAEKHRTV-----LNQILRQSPT--------HLSDGPFAVL 4762
Fly 4763 VDH-TRILDFDVKRKYFQTELER-----LDEGIRREEH---------------TVSVRRVTVFED 4806
Fly 4807 SFRVLYRLGPEEWKNRFYIVFEDEEGQDAGGLLREWYVIISREIFNPMYALFCVSPGDRVTYMIN 4871
Fly 4872 PSSHANPNHLSYFKFVGRVIAKAVHDNKLLECYFTRSFYKHILGKQVKHTDMESQDYEFYKGLDY 4936
Fly 4937 LMKNDISTLGYELTFSTEVQEFGVTQIRDLKPNGRDTAVTEENKFEYVQLVCQLKMSGSIRQQLD 5001
Fly 5002 AFLEGFYDIIPKHLISIFNEQELELLISGLPDIDIEDLKANTEYHKYTSKSAQIQWFWRALRSFD 5066
Fly 5067 QADRAKFLQFVTGTSKVPLQGFGSLEGMNGIQKFQIHRDDRSTDRLPCAHTCFNQLDLPMYKSYD 5131
Fly 5132 KLRSCLLKAIHECSEGFG 5149 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HUWE1 | NP_001285288.1 | DUF908 | 90..326 | CDD:283630 | |
| DUF913 | 621..989 | CDD:283642 | |||
| UBA_like_SF | 1467..1506 | CDD:304366 | |||
| WWE | 1756..1828 | CDD:128922 | |||
| 40S_SA_C | 3575..3651 | CDD:292740 | |||
| DUF4414 | 3675..3779 | CDD:291075 | |||
| HECTc | 4796..5149 | CDD:238033 | 152/352 (43%) | ||
| HECTc | 4820..5148 | CDD:214523 | 141/327 (43%) | ||
| WWP2 | NP_001257383.1 | C2_E3_ubiquitin_ligase | 17..142 | CDD:175988 | 33/182 (18%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 151..299 | 35/187 (19%) | |||
| Atrophin-1 | <164..343 | CDD:331285 | 40/220 (18%) | ||
| WW | 302..331 | CDD:306827 | 5/30 (17%) | ||
| WW | 332..361 | CDD:306827 | 6/28 (21%) | ||
| WW | 407..435 | CDD:306827 | 5/27 (19%) | ||
| WW | 447..477 | CDD:238122 | 8/30 (27%) | ||
| HECTc | 516..868 | CDD:238033 | 152/353 (43%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5021 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||