Protein Alignment HPRT1 and PGM2

DIOPT Version :10

• Sequence 1: NP_000185.1
• Gene: HPRT1 / 3251
• HGNCID: 5157
• Length: 218
• Species: Homo sapiens
• Sequence 2: NP_013823.1
• Gene: PGM2 / 855131
• SGDID: S000004711
• Length: 569
• Species: Saccharomyces cerevisiae
• Alignment Length: 149
• Identity: 33/149 - (22%)
• Similarity: 52/149 - (34%)
• Gaps: 55/149 - (36%)

Human    70 GGYKFFADLL--------DYIKALNRNSDRSIPMTVDFIRLKSYC-NDQSTGDIKVIGGDDLSTL 125
            |..|.:..||        ||:..|..        ..||..:|.:. |.:||.:.|:: .|.::.:
Yeast   174 GKNKKYGPLLVDIIDITKDYVNFLKE--------IFDFDLIKKFIDNQRSTKNWKLL-FDSMNGV 229

Human   126 T---GKNVLIVEDIIDTGKTMQTLLSLVRQYNPK----------MVKVASLLVKRTPRS------ 171
            |   ||.:.:.|..:...:.:|       .::|.          .:..||.||||..|.
Yeast   230 TGPYGKAIFVDEFGLPADEVLQ-------NWHPSPDFGGMHPDPNLTYASSLVKRVDREKIEFGA 287

Human   172 -----------VGYKPDFV 179
                       .||.|.||
Yeast   288 ASDGDGDRNMIYGYGPSFV 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPRT1	NP_000185.1	PRTases_typeI	8..218	CDD:444823	33/149 (22%)
PGM2	NP_013823.1	PGM1	6..569	CDD:100087	33/149 (22%)