Protein Alignment HPRT1 and PGM1

DIOPT Version :10

• Sequence 1: NP_000185.1
• Gene: HPRT1 / 3251
• HGNCID: 5157
• Length: 218
• Species: Homo sapiens
• Sequence 2: NP_012795.1
• Gene: PGM1 / 853732
• SGDID: S000001610
• Length: 570
• Species: Saccharomyces cerevisiae
• Alignment Length: 141
• Identity: 30/141 - (21%)
• Similarity: 45/141 - (31%)
• Gaps: 64/141 - (45%)

Human    71 GYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVED 135
            |:|||..|.|..|.                   |.|.::|.|             ||.|.:..:|
Yeast   361 GWKFFCALFDAKKL-------------------SICGEESFG-------------TGSNHIREKD 393

Human   136 IIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFR 200
            .:........:|::..:.||:  |.||:..                 |.|:|       :|||.|
Yeast   394 GLWAIIAWLNILAIYHRRNPE--KEASIKT-----------------IQDEF-------WNEYGR 432

Human   201 ------DLNHV 205
                  |..|:
Yeast   433 TFFTRYDYEHI 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPRT1	NP_000185.1	PRTases_typeI	8..218	CDD:444823	30/141 (21%)
PGM1	NP_012795.1	phosphohexomutase	8..570	CDD:476822	30/141 (21%)