Protein Alignment HPRT1 and XPT1

DIOPT Version :10

• Sequence 1: NP_000185.1
• Gene: HPRT1 / 3251
• HGNCID: 5157
• Length: 218
• Species: Homo sapiens
• Sequence 2: NP_012667.1
• Gene: XPT1 / 853597
• SGDID: S000003894
• Length: 209
• Species: Saccharomyces cerevisiae
• Alignment Length: 198
• Identity: 44/198 - (22%)
• Similarity: 79/198 - (39%)
• Gaps: 57/198 - (28%)

Human    33 ERVFIPHGLIMDRTERLARDVMKEMGGHHIVA-------LCVLKGGYKFFADLL-DYIKALNRNS 89
            ||::|.:..|    .:|.:.|.|     ||:|       :..:.||....|.:: .::|.   ..
Yeast     5 ERMYISYNNI----HKLCQGVAK-----HILARNERPDIIIAITGGGMIPARIIRSFLKT---KG 57

Human    90 DRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLST--------------LTGKNVLIVEDIIDTG 140
            .::||  :..|.|..|.:......::.||.:.:.|              |.||.||||:::.||.
Yeast    58 QKNIP--IQAIGLSLYEDLGLDNSVETIGKEVIRTQWLDFGALNQHFDSLIGKKVLIVDEVDDTR 120

Human   141 KTMQTLLS------------LVRQYNPKMVKVASLLVKRTPRSVGYKPD-------FVGFE-IPD 185
            .|:...:|            |.|.....::.:..|..|..|:..|. ||       ::..: :||
Yeast   121 TTLHYAVSELEKEIAEQQKVLNRMSEETVISIFVLHNKDKPKRAGL-PDSMMNSGRYIAAQTVPD 184

Human   186 KFV 188
            |::
Yeast   185 KWL 187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPRT1	NP_000185.1	PRTases_typeI	8..218	CDD:444823	44/198 (22%)
XPT1	NP_012667.1	Hpt1	1..195	CDD:441837	44/198 (22%)