Protein Alignment HPRT1 and HPT1

DIOPT Version :10

• Sequence 1: NP_000185.1
• Gene: HPRT1 / 3251
• HGNCID: 5157
• Length: 218
• Species: Homo sapiens
• Sequence 2: NP_010687.3
• Gene: HPT1 / 852008
• SGDID: S000002807
• Length: 221
• Species: Saccharomyces cerevisiae
• Alignment Length: 171
• Identity: 42/171 - (24%)
• Similarity: 63/171 - (36%)
• Gaps: 39/171 - (22%)

Human    36 FIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFI 100
            |||        .|:.|..:||.|...|          :.||.:|...:.||........:.|...
Yeast    41 FIP--------ARILRTFLKEPGVPTI----------RIFAIILSLYEDLNSVGSEVEEVGVKVS 87

Human   101 RLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLV 165
            |.:....:|...|           |.|||||||:::.||..|:...||.:.:...:..|...:..
Yeast    88 RTQWIDYEQCKLD-----------LVGKNVLIVDEVDDTRTTLHYALSELEKDAAEQAKAKGIDT 141

Human   166 KRTPRSVGYKPDFVGFEIPDK-------FVVGYALDYNEYF 199
            :::|.   .|.:|..|.:.||       .......|.|.||
Yeast   142 EKSPE---MKTNFGIFVLHDKQKPKKADLPAEMLNDKNRYF 179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPRT1	NP_000185.1	PRTases_typeI	8..218	CDD:444823	42/171 (25%)
HPT1	NP_010687.3	Hpt1	1..194	CDD:441837	42/171 (25%)