Protein Alignment HPRT1 and hprt1

DIOPT Version :10

• Sequence 1: NP_000185.1
• Gene: HPRT1 / 3251
• HGNCID: 5157
• Length: 218
• Species: Homo sapiens
• Sequence 2: XP_012823623.2
• Gene: hprt1 / 394936
• XenbaseID: XB-GENE-1014679
• Length: 226
• Species: Xenopus tropicalis
• Alignment Length: 208
• Identity: 188/208 - (90%)
• Similarity: 202/208 - (97%)
• Gaps: 0/208 - (0%)

Human    10 ISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKF 74
            |.|||.||||||||||.|||.|||:|:||||||||||||||||:||:||||||||||||||||||
 Frog    18 IQDDEQGYDLDLFCIPKHYAADLEKVYIPHGLIMDRTERLARDIMKDMGGHHIVALCVLKGGYKF 82

Human    75 FADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDT 139
            ||||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||
 Frog    83 FADLLDYIKALNRNSDKSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDT 147

Human   140 GKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNH 204
            ||||:|||:::::||||||||||||||||||||||:|||||||:|||||||||||||||||||||
 Frog   148 GKTMKTLLAMLKKYNPKMVKVASLLVKRTPRSVGYRPDFVGFEVPDKFVVGYALDYNEYFRDLNH 212

Human   205 VCVISETGKAKYK 217
            :|||||.||.|||
 Frog   213 ICVISEDGKEKYK 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPRT1	NP_000185.1	PRTases_typeI	8..218	CDD:444823	188/208 (90%)
hprt1	XP_012823623.2	PRTases_typeI	21..226	CDD:444823	186/205 (91%)