DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment HPRT1 and CG16984

DIOPT Version :10

Sequence 1:NP_000185.1 Gene:HPRT1 / 3251 HGNCID:5157 Length:218 Species:Homo sapiens
Sequence 2:NP_647729.1 Gene:CG16984 / 38322 FlyBaseID:FBgn0062517 Length:307 Species:Drosophila melanogaster


Alignment Length:405 Identity:83/405 - (20%)
Similarity:129/405 - (31%) Gaps:138/405 - (34%)


- Green bases have known domain annotations that are detailed below.


Human   682 GFNHLEELPSFSSRSLGSSQEYAKESG----------SQNKVKHMANQLLAKFEENTRNPSVVKQ 736
            |||:.:..|.|     ||:..:|:.:.          .||....: .|..:.|.:|| ||::|:.
  Fly   505 GFNNSQSSPLF-----GSNPSFAQNTTPAFSQTSPLFGQNTTPAL-GQSSSVFGQNT-NPALVQS 562

Human   737 DCRRVSGIGKPVLCSASRPPGTSCCPKLEESTPRLPP--------PL---------KRQFSSTV- 783
            :.......|.....|:|....||..| ..:.||.:.|        ||         :.|.::|. 
  Fly   563 NTFSTPSTGFGNTFSSSSSLTTSISP-FGQITPAVTPFQSAQPTQPLGAFGFNNFGQTQIANTTD 626

Human   784 ---ATGQVLR-ELNQVPASGECPSRPWRARAKSDLQLGGVEN-LATLPRTCQGALALSGVLRRLQ 843
               |.|...: ...|.||.|.          .:.:|...|.| ..|||...|.::|..|....:|
  Fly   627 IAGAMGTFSQGNFKQQPALGN----------SAVMQPTPVTNPFGTLPALPQISIAQGGNSPSIQ 681

Human   844 ------QVEEK--------------VLQKRAQNLANREFHTKNIKEKAAHLASMFGHGDLPQLTV 888
                  .|.:|              :||:|.: |..|::...:...|....:....:...|:...
  Fly   682 YGISSMPVVDKPAPVRVSPLLTSRHLLQRRVR-LPTRKYRPSDDGPKVPFFSDEEENSSTPKADA 745

Human   889 ----------------------------------GKVSSGI--GAAAEVLVNLYLNDHRP----- 912
                                              ||.|:|:  ||..|...|..:.:..|     
  Fly   746 FFIPRENPRALFIRPVERVKSEHPKDSPTPLQENGKRSNGVTNGANHETKDNGAIREAPPVKVNQ 810

Human   913 KTQATSPDLESPRKAFPLSLGGRDTCYFCKKRVYMIERLSAEGHFFHQECF---RCSVCSATLRL 974
            |...|..:....:.....|..|.|           ||.|..:.|  |.|.|   |....:|..|:
  Fly   811 KQNGTHENHGGDKNGSHSSPSGAD-----------IESLMPKLH--HSEYFTEPRIQELAAKERV 862

Human   975 AAYAFDCDEGKFYCK 989
                   ::|  |||
  Fly   863 -------EQG--YCK 868

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HPRT1NP_000185.1 PRTases_typeI 8..218 CDD:444823
CG16984NP_647729.1 Enkurin 184..298 CDD:464004
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.