Protein Alignment HPRT1 and hprt-1

DIOPT Version :10

• Sequence 1: NP_000185.1
• Gene: HPRT1 / 3251
• HGNCID: 5157
• Length: 218
• Species: Homo sapiens
• Sequence 2: NP_493545.1
• Gene: hprt-1 / 173323
• WormBaseID: WBGene00013690
• Length: 214
• Species: Caenorhabditis elegans
• Alignment Length: 212
• Identity: 107/212 - (50%)
• Similarity: 135/212 - (63%)
• Gaps: 7/212 - (3%)

Human     9 VISDDEPGYDL--DLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGG 71
            ||.||   ::|  |.|.||..|..||..|.||.||:.||..|||:|:..|:|...|..||||||.
 Worm     7 VIPDD---FELPVDAFDIPICYDGDLSGVVIPEGLVRDRVRRLAKDIHAEIGNKPIALLCVLKGS 68

Human    72 YKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDI 136
            ||||..|::  :..|..|....||||||||:|||.:..|||.|:::|..:|..|.||:||:|:||
 Worm    69 YKFFTALVE--ELTNARSSCPEPMTVDFIRVKSYEDQMSTGQIQIMGLSNLDELKGKSVLVVDDI 131

Human   137 IDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRD 201
            .|||:|:..|||.:.:...:....|.||.||..|.|....|||.|||||||:|||.||||:.|||
 Worm   132 SDTGRTLAKLLSTLHETGVEKTWTALLLSKRVKRVVDVPEDFVAFEIPDKFIVGYGLDYNQKFRD 196

Human   202 LNHVCVISETGKAKYKA 218
            |.|:||:|..|..|||:
 Worm   197 LGHICVMSPAGIEKYKS 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPRT1	NP_000185.1	PRTases_typeI	8..218	CDD:444823	106/210 (50%)
hprt-1	NP_493545.1	PRTases_typeI	7..212	CDD:444823	105/209 (50%)