DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9281 and Abcf1

DIOPT Version :9

Sequence 1:	NP_001285284.1	Gene:	CG9281 / 32508	FlyBaseID:	FBgn0030672	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_001103353.1	Gene:	Abcf1 / 85493	RGDID:	620286	Length:	839	Species:	Rattus norvegicus

Alignment Length:	621	Identity:	240/621 - (38%)
Similarity:	362/621 - (58%)	Gaps:	52/621 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KKREAQKKKDARNKKIQQIPSTKKANGVPERELT--EEEKLCAKLEEEARI-------------S 55
            ||...|..::.:.:|..::    |||. |...|:  |::||..:::.|.::             |
  Rat   220 KKGAEQGSEEEKEEKEGEV----KAND-PYAHLSKKEKKKLKKQMDYERQVESLKAANAAENDFS 279

  Fly    56 AEARSCTGSLAVHPRSRDVKIANFSITFFGSELLQDTMLELNCGRRYGLIGLNGCGKSSLLAVLG 120
            ......:...|:...:.|:|:..|||:..|.||..:..|.:..||||||:|.||.||::||..:.
  Rat   280 VSQAEVSSRQAMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIA 344

  Fly   121 GREVPVPPHIDIFHLTREIPASSKSALQCVMEVDEERIKL---EKLAEELAMSEEDDAQEQLIDI 182
            .|.:.:||:||:....:|:.|....|:|.|:..|.:|::|   ||..:......:|.|.|:|..:
  Rat   345 NRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRLRLLEEEKRLQGQLEQGDDTAAEKLEKV 409

  Fly   183 YERLDDMSADLAEVKAARILHGLGFDKAMQQKQAKDFSGGWRMRIALARALFVKPHLLLLDEPTN 247
            ||.|....|..||.||.|||.|||||..||.:..:.||||||||::||||||::|.||:||||||
  Rat   410 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTN 474

  Fly   248 HLDLDACVWLEEELKTYKRILVLISHSQDFLNGVCTNIIHLTGKRLKYYTGNYEAFVRTRMELLE 312
            ||||:|.:||...|:.:::.|:::||.|.||:.|||:||||..:||.||.|||..|.:...:..:
  Rat   475 HLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDTQRLHYYRGNYMTFKKMYQQKQK 539

  Fly   313 NQMKQYNWEQDQISHMKNYIARFGHGSAKLARQAQSKEKTLAKMVAQGLTEKVSDDK-------- 369
            ..:|||..::.::..:|        ...|..:||:.:.|.:.....|....|..|::
  Rat   540 ELLKQYEKQEKKLKELK--------AGGKSTKQAEKQTKEVLTRKQQKCRRKNQDEESQDPPELL 596

  Fly   370 ------VLNFYFPSCGKVPPPVIMVQNVNFRYNDETPWIYKNLEFGIDLDTRLALVGPNGAGKST 428
                  .:.|.||....:.|||:.:..|.|.|..:.| ::|||:||||:|:|:.:|||||.||||
  Rat   597 KRPREYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKP-LFKNLDFGIDMDSRICIVGPNGVGKST 660

  Fly   429 LLKLLYGDLVPTSGMIRKNSHLRIARYHQHLHELLDLDASPLEYMMRAF--PDVKEKEEMRKIIG 491
            ||.||.|.|.||:|.:|||..|:|..::|...|.|.::.:|.||:.|.|  |    .::.||.:|
  Rat   661 LLLLLTGKLTPTNGEMRKNHRLKIGFFNQQYAEQLHMEETPTEYLQRGFNLP----YQDARKCLG 721

  Fly   492 RYGLTGRQQVCPIRQLSDGQRCRVVFAWLAWQVPHLLLLDEPTNHLDMETIDALADAINDFDGGM 556
            |:||........|.:||.||:.|||||.||.:.|.:|:||||||:||:|:||||.:|||::.|.:
  Rat   722 RFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAV 786

  Fly   557 VLVSHDFRLINQVAEEIWVCEKETVTKWKGGILDYK 592
            ::||||.|||.:...::||.|:::|::..|...|||
  Rat   787 IVVSHDARLITETNCQLWVVEEQSVSQIDGDFDDYK 822

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9281	NP_001285284.1	Uup	71..597	CDD:223562	225/541 (42%)
		ABCF_EF-3	74..292	CDD:213188	102/220 (46%)
		ABC_tran_Xtn	286..373	CDD:289608	22/100 (22%)
		ABCF_EF-3	386..578	CDD:213188	91/193 (47%)
Abcf1	NP_001103353.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..258		12/42 (29%)
		Uup	296..827	CDD:223562	225/540 (42%)
		ABCF_EF-3	298..519	CDD:213188	102/220 (46%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	553..600		8/54 (15%)
		ABCF_EF-3	621..809	CDD:213188	92/192 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53504
OrthoDB	1	1.010	-	-		D249617at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.830