DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9281 and Abcf3

DIOPT Version :9

Sequence 1:	NP_001285284.1	Gene:	CG9281 / 32508	FlyBaseID:	FBgn0030672	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_038880.1	Gene:	Abcf3 / 27406	MGIID:	1351656	Length:	709	Species:	Mus musculus

Alignment Length:	606	Identity:	247/606 - (40%)
Similarity:	366/606 - (60%)	Gaps:	24/606 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SAAKKREAQKKKDARNKKIQQIPSTKKANGVPERELTEEEKLCAKLEEEARISAEARSCTGSLAV 67
            :|.|..:|:.:..|:.:|..:..:.|.:|.:...|.:..:   |...:|:|:.:..::
Mouse   119 NAKKLEKAEARLKAKQEKRSEKETLKTSNPLVLEEASASQ---AGSRKESRLESSGKN------- 173

  Fly    68 HPRSRDVKIANFSITFFGSELLQDTMLELNCGRRYGLIGLNGCGKSSLLAVLGGREVPVPPHIDI 132
              :|.||:|.||.::|....||....:.|..||||||:|.||.||::||.:|..|.:.||.||.:
Mouse   174 --KSYDVRIENFDVSFGDRVLLAGADVNLAWGRRYGLVGRNGLGKTTLLKMLATRSLRVPAHISL 236

  Fly   133 FHLTREIPASSKSALQCVMEVDEERIKLEKLAEELAM-----SEEDDAQEQLIDIYERLDDMSAD 192
            .|:.:|:......|||.|:|.|..|..|.:...||::     ..|.....||.:||.:|:::.||
Mouse   237 LHVEQEVAGDDTPALQSVLESDTVREDLLRQERELSLRIAAGRAEGSEAAQLAEIYGKLEEIEAD 301

  Fly   193 LAEVKAARILHGLGFDKAMQQKQAKDFSGGWRMRIALARALFVKPHLLLLDEPTNHLDLDACVWL 257
            .|..:|:.||.||||...|||:..::||||||||:|||||||.:|.|||||||||.||:.|.:||
Mouse   302 KAPARASVILAGLGFTPKMQQQPTREFSGGWRMRLALARALFARPDLLLLDEPTNMLDVRAILWL 366

  Fly   258 EEELKTYKRILVLISHSQDFLNGVCTNIIHLTGKRLKYYTGNYEAFVRTRMELLENQMKQYNWEQ 322
            |..|:|:...::::||.::|||.:.|:||||..:||..|.|::|.|::::.|.|.||.::|..:|
Mouse   367 ENYLQTWPSTILVVSHDRNFLNAIATDIIHLHSQRLDGYRGDFETFIKSKQERLLNQQREYEAQQ 431

  Fly   323 DQISHMKNYIARFGHGSAKLARQAQSKEKTLAKMVAQGLTEKVSDDKVLNFYFP-SCGKVPPPVI 386
            ....|::.:|.||.: :|..|.|.|||.|.|.|:......:|.| :.||.  || ...|..||::
Mouse   432 QYRQHIQVFIDRFRY-NANRASQVQSKLKMLEKLPELKPVDKES-EVVLK--FPDGFEKFSPPIL 492

  Fly   387 MVQNVNFRYNDETPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPTSGMIRKNSHLR 451
            .:..|:| |.|....|:..|....||::|:.:||.|||||||:||||.|||.|..|:...:.:|:
Mouse   493 QLDEVDF-YYDPKHSIFSRLSVSADLESRICVVGENGAGKSTMLKLLMGDLSPVRGIRHAHRNLK 556

  Fly   452 IARYHQHLHELLDLDASPLEYMMRAFPDVKEKEEMRKIIGRYGLTGRQQVCPIRQLSDGQRCRVV 516
            |..:.||..|.|||:.|.:|.:.|.||.:.| ||.|..:||||::|...:.|:..||.||:.||.
Mouse   557 IGYFSQHHVEQLDLNVSAVELLARKFPGLPE-EEYRHQLGRYGISGELAMRPVASLSGGQKSRVA 620

  Fly   517 FAWLAWQVPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRLINQVAEEIWVCEKETV 581
            ||.:....|:..:|||||||||||||:||..|:|:|.||::|||||.|.|..|.:|:||||..:|
Mouse   621 FAQMTMPCPNFYILDEPTNHLDMETIEALGQALNNFRGGVILVSHDERFIRLVCKELWVCENGSV 685

  Fly   582 TKWKGGILDYKDHLKNKITSE 602
            |:.:||...|:..|:.:...|
Mouse   686 TRVEGGFDQYRALLQEQFRRE 706

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9281	NP_001285284.1	Uup	71..597	CDD:223562	235/531 (44%)
		ABCF_EF-3	74..292	CDD:213188	101/222 (45%)
		ABC_tran_Xtn	286..373	CDD:289608	32/86 (37%)
		ABCF_EF-3	386..578	CDD:213188	91/191 (48%)
Abcf3	NP_038880.1	PLN03073	6..700	CDD:215558	245/598 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	129..171		8/44 (18%)
		ABCF_EF-3	178..401	CDD:213188	101/222 (45%)
		P-loop_NTPase	266..>363	CDD:304359	48/96 (50%)
		ABC_tran_Xtn	395..477	CDD:289608	30/83 (36%)
		ABCF_EF-3	492..683	CDD:213188	92/192 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53504
OrthoDB	1	1.010	-	-		D249617at33208
OrthoFinder	1	1.000	-	-		FOG0000863
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830