DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9281 and abcf-3

DIOPT Version :9

Sequence 1:	NP_001285284.1	Gene:	CG9281 / 32508	FlyBaseID:	FBgn0030672	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_498339.1	Gene:	abcf-3 / 175873	WormBaseID:	WBGene00018339	Length:	712	Species:	Caenorhabditis elegans

Alignment Length:	638	Identity:	237/638 - (37%)
Similarity:	368/638 - (57%)	Gaps:	47/638 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSAAKKREAQKKK-------DARNKKIQQIPSTKKANGVPERELTEEEKLCAKLEEEARISAEA 58
            :..|.|::||..|:       .|.|:..:.:.|..|.. ..:...|.::|..||.|:.|...|||
Worm    79 LPKAIKQQEATTKRLEQTVDMAAENQNFEALQSIWKVQ-TRDTPTTVDKKKLAKAEDRAAAKAEA 142

  Fly    59 R--------------SCTGSLAVHP---------RSRDVKIANFSITFFGSELLQDTMLELNCGR 100
            |              |.|.|.|  |         .|:|:|:.:..|:....:||....:.:..||
Worm   143 RADAPVERKKKKNEPSATASQA--PIRDSGARGANSKDIKLESVDISIGTKQLLSCADVTMAFGR 205

  Fly   101 RYGLIGLNGCGKSSLLAVLGGREVPVPPHIDIFHLTREIPASSKSALQCVMEVDEERIKL---EK 162
            ||||:|.||.||::||.::..:::.:|..|.:..:.:|:.......|..|:..|.:|..|   ||
Worm   206 RYGLVGRNGIGKTTLLKMISSQQLKIPAGISMLSVEQEVEGDDTLVLDAVLMSDTKRQTLLDREK 270

  Fly   163 -LAEELAMSEEDDAQ-----EQLIDIYERLDDMSADLAEVKAARILHGLGFDKAMQQKQAKDFSG 221
             |...:.....:||:     ::|..:|..::.:..|.|..:|:.:|:||||....|::..|:|||
Worm   271 TLQSRINKDNINDAEKTKWNDELSKLYIEMEALQLDKAPARASSLLYGLGFTPDEQKRPTKEFSG 335

  Fly   222 GWRMRIALARALFVKPHLLLLDEPTNHLDLDACVWLEEELKTYKRILVLISHSQDFLNGVCTNII 286
            |||||:||||||||||.|||||||||.||:.|..|||..|:.::..::.:||.:.|||.:||:|:
Worm   336 GWRMRVALARALFVKPDLLLLDEPTNMLDMRAVYWLEGHLQGWEGTILTVSHDRKFLNEICTDIV 400

  Fly   287 HLTGKRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQISHMKNYIARFGHGSAKLARQAQSKEK 351
            ||..:||.:|.|||:.|.:|..|.|..|.::|..:|....|.:.:|.:|.: :||.|...||:.|
Worm   401 HLHTRRLDHYKGNYDQFEKTMKEKLTQQQREYESQQQLRQHTQEFIDKFRY-NAKRAPMVQSRIK 464

  Fly   352 TLAKMVAQGLTEKVSDDKVLNFYFPSCGKVPPPVIMVQNVNFRYNDETPWIYKNLEFGIDLDTRL 416
            .|.|:......|..||   ::|.||.|..:..||:.:..|:||||:::|::::.|..|...::|:
Worm   465 MLEKLPVLLPVELESD---IHFKFPECEVLSNPVLQLDEVSFRYNEDSPYLFRKLNLGTHANSRI 526

  Fly   417 ALVGPNGAGKSTLLKLLYGDLVPTSGMIRKNSHLRIARYHQHLHELLDLDASPLEYMMRAFPDVK 481
            .:||.|||||:||||||..||.|:.|:...|..:|||.:.||..:.||::.|.:|.:|:..|. |
Worm   527 CIVGENGAGKTTLLKLLLDDLQPSVGLRNVNRRIRIAYFTQHHVDQLDMETSAIEVLMKNHPG-K 590

  Fly   482 EKEEMRKIIGRYGLTGRQQVCPIRQLSDGQRCRVVFAWLAWQVPHLLLLDEPTNHLDMETIDALA 546
            .:|:.|..:||:||.|...:..:..||.||:.|:.||.||...|:.|:|||||||||:||::||.
Worm   591 TQEDYRAALGRFGLAGDMALQSVETLSGGQKSRLAFANLALMQPNYLILDEPTNHLDVETVEALG 655

  Fly   547 DAINDFDGGMVLVSHDFRLINQVAEEIWVCEKETVTKWKGGILDYKDHLKNKI 599
            .|:|.|:||:||||||.:||..|.:|:||.:...||..:||:.:|:..:..::
Worm   656 KALNVFNGGVVLVSHDEQLIELVCKELWVVKDRMVTTLEGGLEEYRKQVYKQL 708

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9281	NP_001285284.1	Uup	71..597	CDD:223562	213/534 (40%)
		ABCF_EF-3	74..292	CDD:213188	86/226 (38%)
		ABC_tran_Xtn	286..373	CDD:289608	29/86 (34%)
		ABCF_EF-3	386..578	CDD:213188	87/191 (46%)
abcf-3	NP_498339.1	PLN03073	22..702	CDD:215558	237/630 (38%)
		ABCF_EF-3	179..406	CDD:213188	86/226 (38%)
		ABC_tran_Xtn	400..483	CDD:289608	29/86 (34%)
		ABCF_EF-3	496..688	CDD:213188	87/192 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53504
OrthoDB	1	1.010	-	-		D249617at33208
OrthoFinder	1	1.000	-	-		FOG0000863
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830