Protein Alignment CG9281 and ABCF2

DIOPT Version :9

• Sequence 1: NP_001285284.1
• Gene: CG9281 / 32508
• FlyBaseID: FBgn0030672
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_009120.1
• Gene: ABCF2 / 10061
• HGNCID: 71
• Length: 623
• Species: Homo sapiens
• Alignment Length: 614
• Identity: 427/614 - (69%)
• Similarity: 502/614 - (81%)
• Gaps: 14/614 - (2%)

  Fly     4 AAKKREAQKKKDARNKKIQ---------QIPSTKKANGVPERELTEEEKLCAKLEEEARISAEAR 59
            ||||:||.|.:....|..:         |:....:|||   ||.||.:.|..:||:.....|.||
Human    10 AAKKKEAAKARQRPRKGHEENGDVVTEPQVAEKNEANG---RETTEVDLLTKELEDFEMKKAAAR 71

  Fly    60 SCTGSLAVHPRSRDVKIANFSITFFGSELLQDTMLELNCGRRYGLIGLNGCGKSSLLAVLGGREV 124
            :.||.||.||.|.||.|.|.|:||.|.|||.||.||||.|||||||||||.|||.||:.:|.|||
Human    72 AVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLSAIGKREV 136

  Fly   125 PVPPHIDIFHLTREIPASSKSALQCVMEVDEERIKLEKLAEELAMSEEDDAQEQLIDIYERLDDM 189
            |:|.||||:|||||:|.|.|:.|.||||||.||..|||.||.||  .||...|:|:::||||:::
Human   137 PIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLA--HEDAECEKLMELYERLEEL 199

  Fly   190 SADLAEVKAARILHGLGFDKAMQQKQAKDFSGGWRMRIALARALFVKPHLLLLDEPTNHLDLDAC 254
            .||.||::|:||||||||..|||:|:.||||||||||:|||||||::|.:|||||||||||||||
Human   200 DADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRPFMLLLDEPTNHLDLDAC 264

  Fly   255 VWLEEELKTYKRILVLISHSQDFLNGVCTNIIHLTGKRLKYYTGNYEAFVRTRMELLENQMKQYN 319
            |||||||||:||||||:||||||||||||||||:..|:||||||||:.:|:||:||.|||||:::
Human   265 VWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYTGNYDQYVKTRLELEENQMKRFH 329

  Fly   320 WEQDQISHMKNYIARFGHGSAKLARQAQSKEKTLAKMVAQGLTEKVSDDKVLNFYFPSCGKVPPP 384
            ||||||:|||||||||||||||||||||||||||.||:|.||||:|..||.|:||||.|||:|||
Human   330 WEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPP 394

  Fly   385 VIMVQNVNFRYNDETPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPTSGMIRKNSH 449
            |||||||:|:|..:.|.||.|||||||||||:|||||||||||||||||.|:|:||.|||||:||
Human   395 VIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSH 459

  Fly   450 LRIARYHQHLHELLDLDASPLEYMMRAFPDVKEKEEMRKIIGRYGLTGRQQVCPIRQLSDGQRCR 514
            ::|.||||||.|.||||.|||||||:.:|::|||||||||||||||||:|||.|||.|||||:||
Human   460 VKIGRYHQHLQEQLDLDLSPLEYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCR 524

  Fly   515 VVFAWLAWQVPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRLINQVAEEIWVCEKE 579
            |..||||||.||:|.|||||||||:|||||||||||:|:|||:|||||||||.|||:|||||||:
Human   525 VCLAWLAWQNPHMLFLDEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQ 589

  Fly   580 TVTKWKGGILDYKDHLKNKITSENEKKAK 608
            |:|||.|.||.||:|||:|:..|..:..|
Human   590 TITKWPGDILAYKEHLKSKLVDEEPQLTK 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9281	NP_001285284.1	Uup	71..597	CDD:223562	395/525 (75%)
		ABCF_EF-3	74..292	CDD:213188	155/217 (71%)
		ABC_tran_Xtn	286..373	CDD:289608	65/86 (76%)
		ABCF_EF-3	386..578	CDD:213188	151/191 (79%)
ABCF2	NP_009120.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..51		14/43 (33%)
		Uup	83..603	CDD:223562	392/521 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159129
Domainoid	1	1.000	227	1.000	Domainoid score	I2505
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H21408
Inparanoid	1	1.050	869	1.000	Inparanoid score	I424
Isobase	1	0.950	-	0	Normalized mean entropy	S359
OMA	1	1.010	-	-		QHG53504
OrthoDB	1	1.010	-	-		D249617at33208
OrthoFinder	1	1.000	-	-		FOG0000863
OrthoInspector	1	1.000	-	-		oto88655
orthoMCL	1	0.900	-	-		OOG6_102940
Panther	1	1.100	-	-	LDO	PTHR19211
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1733
SonicParanoid	1	1.000	-	-		X3141
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	15	14.890