Protein Alignment CG8134 and F8A1

DIOPT Version :9

• Sequence 1: NP_001285283.1
• Gene: CG8134 / 32507
• FlyBaseID: FBgn0030671
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_036283.2
• Gene: F8A1 / 8263
• HGNCID: 3547
• Length: 371
• Species: Homo sapiens
• Alignment Length: 397
• Identity: 90/397 - (22%)
• Similarity: 125/397 - (31%)
• Gaps: 154/397 - (38%)

  Fly     9 LGGGGSSSGAPSTAPGHEHHQLEQYQYPKNLIEQYLRASSKIKKFERAGFFKRF--APSVVDVQA 71
            |||||:       .||.|         ..:.:.:|...|:|:|        |||  .|:|.:...
Human     8 LGGGGA-------GPGPE---------AGDFLARYRLVSNKLK--------KRFLRKPNVAEAGE 48

  Fly    72 DFQRLAYSFEESGIQQYAAMCHIGYAKCESYGGAPQRESEAYLRAARSFL-------------AA 123
            .|.:|...........|||.|.:..|:|:........|:.|...|||.||             ||
Human    49 QFGQLGRELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQERDARQRLVCPAA 113

  Fly   124 HNE-----------SGRLHLRTRHSGFREGAVHCYHRAADRAVDGCVFKAAILRELKQ------- 170
            :.|           :.||||.....            ||..|:  |:..||.||:|.|
Human   114 YGEPLQAAASALGAAVRLHLELGQP------------AAAAAL--CLELAAALRDLGQPAAAAGH 164

  Fly   171 ----LQRQL----------------------DSTSSFASPT--------HQIHDLE--------- 192
                .|.||                      |.|.:.|..|        |..|.::
Human   165 FQRAAQLQLPQLPLAALQALGEAASCQLLARDYTGALAVFTRMQRLAREHGSHPVQSLPPPPPPA 229

  Fly   193 --------------ISAETSGQRGDFRSALQHYDDIVDNVYERRGARMYGELLRRVEVLRLLLLV 243
                          :....||......:||..:.|:                |.|.||.|:|||:
Human   230 PQPGPGATPALPAALLPPNSGSAAPSPAALGAFSDV----------------LVRCEVSRVLLLL 278

  Fly   244 HLNLPPARQSPAHIKLIEYYYNLAQFESLPCSADDGGSAERPGAFVPEQQQYALAEITCAWVERK 308
            .|..|||:..|.|.:.:|.|         ...|.|....|..|. :||:....|..:..|..|:.
Human   279 LLQPPPAKLLPEHAQTLEKY---------SWEAFDSHGQESSGQ-LPEELFLLLQSLVMATHEKD 333

  Fly   309 MCDLKHL 315
            ...:|.|
Human   334 TEAIKSL 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8134	NP_001285283.1	None
F8A1	NP_036283.2	Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:Q00558	34..36		1/9 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	213..250		2/36 (6%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157823
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28IE5
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52481
OrthoDB	1	1.010	-	-		D1141704at2759
OrthoFinder	1	1.000	-	-		FOG0007113
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6996
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.880