DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pis and cdipt

DIOPT Version :9

Sequence 1:	NP_573055.1	Gene:	Pis / 32506	FlyBaseID:	FBgn0030670	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_996971.1	Gene:	cdipt / 404620	ZFINID:	ZDB-GENE-040426-2536	Length:	213	Species:	Danio rerio

Alignment Length:	214	Identity:	105/214 - (49%)
Similarity:	144/214 - (67%)	Gaps:	8/214 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DNVFIFVPNLIGYARIVLALIAFWFMSTNYVISGWCYVTSALLDAVDGQAARAFNQSTRFGAMLD 71
            :|:|:|||||||||||||||::|:.|......:.:||:.||||||.||.||||.||.|:||||||
Zfish     4 ENIFLFVPNLIGYARIVLALVSFFLMPCCPGPAVFCYLLSALLDAFDGHAARALNQGTKFGAMLD 68

  Fly    72 QLTDRCGTTGLLVTLAYFYPRYMFWFQLSIAIDVACHWLFMQTSVVVGRSSHKVND---NFIMRL 133
            .|||||.|..|||.||..||.|.|.||||:.:|||.|||.:.:|::.|.:|||..|   |.|:||
Zfish    69 MLTDRCATMCLLVNLALLYPSYTFLFQLSMCLDVASHWLHLHSSMMKGATSHKAIDLSGNPILRL 133

  Fly   134 YY-QKDILTFMCCVNELFYVCLYLLHFTYGPLIFGASLFKILAFLTGPFAVLKALISVMHAYVAG 197
            || .:.:|.|||..||||:..||::.:...|.::    .:.|..:.|...:||:.||.:|...|.
Zfish   134 YYTSRPVLFFMCMGNELFFCLLYIMFYIEEPQVW----LQWLLGVCGVVCLLKSGISFLHLITAS 194

  Fly   198 IDLAAVDVRERQERRQKSE 216
            .::||:||.:|::.|.|::
Zfish   195 RNMAAIDVADREKERSKAQ 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pis	NP_573055.1	CDP-OH_P_transf	13..75	CDD:307284	40/61 (66%)
cdipt	NP_996971.1	CDP-OH_P_transf	10..72	CDD:279415	40/61 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586319
Domainoid	1	1.000	111	1.000	Domainoid score	I6223
eggNOG	1	0.900	-	-		E1_COG0558
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7159
Inparanoid	1	1.050	198	1.000	Inparanoid score	I3777
OMA	1	1.010	-	-		QHG53925
OrthoDB	1	1.010	-	-		D1615564at2759
OrthoFinder	1	1.000	-	-		FOG0004202
OrthoInspector	1	1.000	-	-		oto38905
orthoMCL	1	0.900	-	-		OOG6_102569
Panther	1	1.100	-	-	LDO	PTHR15362
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1704
SonicParanoid	1	1.000	-	-		X2946
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800