DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8117 and Med26

DIOPT Version :9

Sequence 1:	NP_573049.2	Gene:	CG8117 / 32499	FlyBaseID:	FBgn0030663	Length:	162	Species:	Drosophila melanogaster
Sequence 2:	NP_081761.2	Gene:	Med26 / 70625	MGIID:	1917875	Length:	588	Species:	Mus musculus

Alignment Length:	87	Identity:	26/87 - (29%)
Similarity:	32/87 - (36%)	Gaps:	24/87 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 LLGQITPEELSKMTPEEMASDDMKQMRQKYVQDSINAAQMAKVQGTKTDQFKCERC-----DKRN 134
            ||...||.:|..:| .|:..||:         |.|.|.|...|.|       ||..     |...
Mouse   519 LLPLPTPTDLPGLT-REVTQDDL---------DRIQAQQWPGVNG-------CEDTQGNWYDWTQ 566

  Fly   135 CSQL--HIRDGDEPIITFVICD 154
            |..|  |..||...|:.:|..|
Mouse   567 CISLDPHGDDGRLNILPYVCLD 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8117	NP_573049.2	TFIIS_M	3..109	CDD:284835	10/33 (30%)
CG8117	NP_573049.2	Zn-ribbon	118..161	CDD:295390	12/44 (27%)
Med26	NP_081761.2	TFS2N	12..86	CDD:197766
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	112..393
		Med26_M	178..405	CDD:292322
		Med26_C	407..586	CDD:292321	24/83 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	412..441
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900