DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8117 and tcea3

DIOPT Version :9

Sequence 1:	NP_573049.2	Gene:	CG8117 / 32499	FlyBaseID:	FBgn0030663	Length:	162	Species:	Drosophila melanogaster
Sequence 2:	XP_005158394.1	Gene:	tcea3 / 402983	ZFINID:	ZDB-GENE-040426-1860	Length:	783	Species:	Danio rerio

Alignment Length:	160	Identity:	78/160 - (48%)
Similarity:	107/160 - (66%)	Gaps:	3/160 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IRIKCREMLATALKSGNMPPGCG-DPDDMAAKLEDAIYGDLNGCKVKYKNRIRSRLANLRDPKNP 68
            ||.||.|||..||::.:.....| :.:.|.|::||.||.:.....:|||||:|||::||:|||||
Zfish   622 IRDKCIEMLTAALRTDDDYKDYGTNCEAMGAEIEDYIYQETKATDMKYKNRVRSRISNLKDPKNP 686

  Fly    69 ELRQKFLLGQITPEELSKMTPEEMASDDMKQMRQKYVQDSINAAQMAKVQGTKTDQFKCERCDKR 133
            .||:..|.|.|....::.||.||||||::||:|....|::|...||||..||.||..:|.:|.|:
Zfish   687 NLRKNVLAGAIELSRIASMTAEEMASDELKQLRNVLTQEAIREHQMAKTGGTTTDLLQCGKCKKK 751

  Fly   134 NC--SQLHIRDGDEPIITFVICDECGNRWK 161
            ||  :|:..|..|||:.|||:|:|||||||
Zfish   752 NCTYNQVQTRSADEPMTTFVLCNECGNRWK 781

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8117	NP_573049.2	TFIIS_M	3..109	CDD:284835	48/104 (46%)
CG8117	NP_573049.2	Zn-ribbon	118..161	CDD:295390	23/44 (52%)
tcea3	XP_005158394.1	TFIIS_I	4..80	CDD:238107
		TFSII	5..>156	CDD:273592
		TFIIS_M	620..727	CDD:284835	48/104 (46%)
		Zn-ribbon_TFIIS	736..782	CDD:259796	25/46 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	130	1.000	Domainoid score	I5163
eggNOG	1	0.900	-	-		E1_COG1594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1579101at2759
OrthoFinder	1	1.000	-	-		FOG0001112
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101177
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2312
SonicParanoid	1	1.000	-	-		X770
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.710