DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8117 and tcea1

DIOPT Version :9

Sequence 1:	NP_573049.2	Gene:	CG8117 / 32499	FlyBaseID:	FBgn0030663	Length:	162	Species:	Drosophila melanogaster
Sequence 2:	NP_956288.1	Gene:	tcea1 / 336105	ZFINID:	ZDB-GENE-030131-8049	Length:	309	Species:	Danio rerio

Alignment Length:	163	Identity:	77/163 - (47%)
Similarity:	115/163 - (70%)	Gaps:	3/163 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SMEIRIKCREMLATALKSGNMPPGCG-DPDDMAAKLEDAIYGDLNGCKVKYKNRIRSRLANLRDP 65
            |..:||||||||:.||::|:.....| |.|::.|::|:.|:.:.....:|||||:|||::||:|.
Zfish   145 SDSVRIKCREMLSNALQTGDDYITIGSDCDELGAQIEECIFLEFKNTDMKYKNRVRSRISNLKDA 209

  Fly    66 KNPELRQKFLLGQITPEELSKMTPEEMASDDMKQMRQKYVQDSINAAQMAKVQGTKTDQFKCERC 130
            |||.||:..|.|.::|:.::|||.||||||::|:||:...:::|...|:|...||:||.|.|.:|
Zfish   210 KNPNLRRNVLCGNVSPDRIAKMTAEEMASDELKEMRKNLTKEAIRDHQVATSGGTQTDLFTCGKC 274

  Fly   131 DKRNC--SQLHIRDGDEPIITFVICDECGNRWK 161
            .|:.|  :|:..|..|||:.|||.|:|||||||
Zfish   275 KKKKCTYTQVQTRSADEPMTTFVFCNECGNRWK 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8117	NP_573049.2	TFIIS_M	3..109	CDD:284835	48/106 (45%)
CG8117	NP_573049.2	Zn-ribbon	118..161	CDD:295390	23/44 (52%)
tcea1	NP_956288.1	TFIIS_I	6..82	CDD:238107
		TFSII	7..309	CDD:273592	77/163 (47%)
		TFIIS_M	146..253	CDD:284835	48/106 (45%)
		Zn-ribbon_TFIIS	262..308	CDD:259796	25/46 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	130	1.000	Domainoid score	I5163
eggNOG	1	0.900	-	-		E1_COG1594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1579101at2759
OrthoFinder	1	1.000	-	-		FOG0001112
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101177
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2312
SonicParanoid	1	1.000	-	-		X770
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.710