DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8117 and Tcea1

DIOPT Version :9

Sequence 1:	NP_573049.2	Gene:	CG8117 / 32499	FlyBaseID:	FBgn0030663	Length:	162	Species:	Drosophila melanogaster
Sequence 2:	NP_001153223.1	Gene:	Tcea1 / 21399	MGIID:	1196624	Length:	312	Species:	Mus musculus

Alignment Length:	163	Identity:	80/163 - (49%)
Similarity:	118/163 - (72%)	Gaps:	3/163 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SMEIRIKCREMLATALKSGNMPPGCG-DPDDMAAKLEDAIYGDLNGCKVKYKNRIRSRLANLRDP 65
            |..:|:|||||||.||::|:.....| |.:::.:::|:|||.::....:|||||:|||::||:|.
Mouse   148 SDSVRLKCREMLAAALRTGDDYVAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDA 212

  Fly    66 KNPELRQKFLLGQITPEELSKMTPEEMASDDMKQMRQKYVQDSINAAQMAKVQGTKTDQFKCERC 130
            |||.||:..|.|.|.|:..::||.||||||::|:||:...:::|...||||..||:||.|.|.:|
Mouse   213 KNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKC 277

  Fly   131 DKRNC--SQLHIRDGDEPIITFVICDECGNRWK 161
            .|:||  :|:..|..|||:.|||:|:|||||||
Mouse   278 KKKNCTYTQVQTRSADEPMTTFVVCNECGNRWK 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8117	NP_573049.2	TFIIS_M	3..109	CDD:284835	48/106 (45%)
CG8117	NP_573049.2	Zn-ribbon	118..161	CDD:295390	24/44 (55%)
Tcea1	NP_001153223.1	TFSII	33..312	CDD:273592	80/163 (49%)
		TFIIS_I	<35..89	CDD:238107
		TFIIS_M	149..256	CDD:284835	48/106 (45%)
		Zn-ribbon_TFIIS	265..311	CDD:259796	26/46 (57%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	128	1.000	Domainoid score	I5287
eggNOG	1	0.900	-	-		E1_COG1594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001112
OrthoInspector	1	1.000	-	-		otm42767
orthoMCL	1	0.900	-	-		OOG6_101177
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2312
SonicParanoid	1	1.000	-	-		X770
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.700