Protein Alignment sog and Chrd

DIOPT Version :10

• Sequence 1: NP_476736.1
• Gene: sog / 32498
• FlyBaseID: FBgn0003463
• Length: 1038
• Species: Drosophila melanogaster
• Sequence 2: XP_006248619.1
• Gene: Chrd / 117275
• RGDID: 620181
• Length: 970
• Species: Rattus norvegicus
• Alignment Length: 1048
• Identity: 275/1048 - (26%)
• Similarity: 413/1048 - (39%)
• Gaps: 235/1048 - (22%)

  Fly    73 GVTEGRRHAPLMFEESDTGRR-SNRPAVTECQFGKVLRELGSTWYADLGPPFGVMYCIKCECVAI 136
            |:|.|.           ||:| ..:|....|.||..:..|..||:.|||.|||||.|:.|.|.|
  Rat    54 GITAGA-----------TGQRPPAKPVPAGCSFGGKVYALDETWHPDLGEPFGVMRCVLCACEA- 106

  Fly   137 P---KKRRIVARVQCRNIKNECPPAKCDDPISLPGKCCKTCPGDRNDTD---VALDVPVPNEEEE 195
            |   ::.|...||.|:|||.:||...|..|..|||.||:|||.:|::.|   ..|....|.:.|.
  Rat   107 PQWARRGRGPGRVSCKNIKPQCPTLACRQPRQLPGHCCQTCPQERSNLDPQPAGLVFEYPRDPEH 171

  Fly   196 RNMK-----------------HYAALLTG-RTSYFLKGEEMKSMYTTYNPQNVVATARFLFHKKN 242
            |:..                 .:.||||| ||                   ..||.||....:.:
  Rat   172 RSYSDRGEPGTGERTRGDGHTDFVALLTGPRT-------------------QAVARARVSLLRSS 217

  Fly   243 LYYSFYTSSRIGRPRAIQFVDDAGVILEEHQLETTLAGTLSVYQNATGKICGVWRRVPRDYKRIL 307
            |.:|. :..|:.||..::|.|..|.||.||....|          ..|.:|||||.|||...|:|
  Rat   218 LRFSI-SYQRLDRPSRVRFTDPTGNILFEHPAAPT----------QDGLVCGVWRAVPRLSVRLL 271

  Fly   308 RDDRLHVVLLWGNKQQAELALAGKVAKYTALQTELFSSLLEAPLPDGKTDPQLAGAGGTAIVSTS 372
            |.::|.|.|:.......|  :.|.:....||..|.||::|..      .||...|.||.|:: |.
  Rat   272 RAEQLRVALVTPTHPSEE--VWGPLIWQGALTAETFSAILTL------EDPLQRGVGGIALL-TL 327

  Fly   373 SGAASSMHLTLVFNGVFGAEEYADAALSVKIELAERKEVIFDEIPRVRKPSAEINVLELSSPISI 437
            |....::|..|:|.|:.|..    |.:.:|:::..:.:::.:  .:....:.|....|:...::.
  Rat   328 SDTEDALHFLLLFRGLLGGL----AHVPLKLQILHQGQLLRE--LQANASAQEPGFAEVLPSLTD 386

  Fly   438 QNLRLMSRGKLLLTVESKKYPHLRIQGHIVTRASCEIFQTLLAPHSA--ESSTKSSGLAWVYLNT 500
            |.:..:..|:|.:.:|....|.|||.|:|.||.||::.|::|....|  ...|.::|.|...|..
  Rat   387 QEMDWLVLGELQMVLEKMGGPELRISGYITTRQSCDVLQSVLCGADALIPVQTGAAGSASFILLG 451

  Fly   501 DGSLAYNIETEHVNTRDRPNISLIEEQGKRKAKLEDLTP----SFNFNQAIGSVEKLGPKVLESL 561
            :|||.|.::.  :.|........:|.:.:||.:...|..    ....:.|:|....||.:....|
  Rat   452 NGSLIYQVQV--IGTGSEVVAMTLETKPQRKNQRTVLCHMAGLQLGGHMAVGVCSGLGARGAHML 514

  Fly   562 YAGELGVNVATE---------HETSL---------------IRGRLVPRPVADARDSAEPILLKR 602
            ...||.:|:.|:         |.|:|               :.|.||..||
  Rat   515 LQNELFLNIGTKDFPDGELRGHVTALCYSGHSAHYDRLPVPLAGALVLPPV-------------- 565

  Fly   603 QEHTDAQNPHAVGMAWMSIDNECNLHYEVTLNGVPAQD---LQLYLEEKPIEAIGAPVTRKLLEE 664
                   ...|.|.||:|:|..|:|||||.|.|:...:   :..:|...|    |.|..::||:.
  Rat   566 -------RSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQGTVTAHLLGPP----GMPGPQRLLKG 619

  Fly   665 FNGSYLEGFFLSMPSAELIKLEMSVCYLEVHSKHSKQLLLRGKLKSTKVPGHC------------ 717
            |.||..:|....:....|..|......|.:.:|.:.:..|||::   .:...|
  Rat   620 FYGSEAQGVVKDLEPVLLRHLTQGTASLLITTKSNPRGELRGQV---HIASQCEVGGLRLASEGV 681

  Fly   718 ---------------FPVYTDNNVPVPGDHNDNHLVNGETKCFHSGRFYNESEQWRSAQDS-CQM 766
                           .|.......|||..|..:........||..|:......:|....|. |.:
  Rat   682 RMSLAPNGEAATSPMLPAGPGPEAPVPAKHGSSGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSL 746

  Fly   767 CACLRGQSSCEVIKCPALKCKSTEQLLQRDGECCPSCVPKKEAADYSAQSSPATNATDLLQQRRG 831
            |.|.|....|:.:.||...|....|.|.   :|||.|..|:.:.|..:..:        |:...|
  Rat   747 CTCQRRTVICDPVVCPPPSCPHPVQALD---QCCPVCPEKQRSRDLPSLPN--------LEPGEG 800

  Fly   832 CRL-GEQ-FHPAGASWHPFLPPNGFDTCTTCSCDPLTLEIRCPRLVCPPLQCSEKLAYRPDKKAC 894
            |.. |:: :..||..|||.:||.|...|..|:|...|.|:.|.::.||.|.|::.:...|..  |
  Rat   801 CYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGATGEVHCEKVQCPRLACAQPVRANPTD--C 863

  Fly   895 CKICPEGKQSSSNGHKTTPNNPNVLQDQAMQRSPSHS--AEEVLANG--GCKVVNKVYENGQEWH 955
            ||.||.|                         |.:|:  .:.:.|:|  ||:...:.:...|.||
  Rat   864 CKQCPVG-------------------------SGTHAKLGDPMQADGPRGCRFAGQWFPENQSWH 903

  Fly   956 PILMSHGEQKCIKCRCKDSKVNCDRKRCSRSTCQQQTRVTSKRRLFEKPDAAAPAIDECCSTQCR 1020
            |.:...||..||.|||.....:|:|..||                  .|.:.....:..|.:.|.
  Rat   904 PSVPPFGEMSCITCRCGAGVPHCERDDCS------------------PPLSCGSGKESRCCSHCT 950

  Fly  1021 RSRRHHKR 1028
            ..|....|
  Rat   951 AQRSSETR 958

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sog	NP_476736.1	VWC	102..174	CDD:278520	35/74 (47%)
		CHRD	200..334	CDD:214804	41/134 (31%)
		CHRD	341..467	CDD:214804	30/125 (24%)
		CHRD	473..585	CDD:214804	30/141 (21%)
		CHRD	594..708	CDD:214804	31/116 (27%)
		VWC	744..803	CDD:278520	18/59 (31%)
		VWC	832..898	CDD:278520	24/67 (36%)
		VWC	941..1017	CDD:278520	18/75 (24%)
Chrd	XP_006248619.1	VWC	73..147	CDD:450195	35/74 (47%)
		CHRD	192..295	CDD:214804	41/134 (31%)
		CHRD	303..416	CDD:214804	30/125 (24%)
		CHRD	422..539	CDD:214804	26/118 (22%)
		CHRD	552..664	CDD:214804	36/139 (26%)
		VWC	723..780	CDD:450195	18/59 (31%)
		VWC	801..867	CDD:214564	24/67 (36%)
		VWC	889..949	CDD:450195	18/77 (23%)