DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9220 and CSGALNACT2

DIOPT Version :9

Sequence 1:	NP_001285280.1	Gene:	CG9220 / 32497	FlyBaseID:	FBgn0030662	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_061060.3	Gene:	CSGALNACT2 / 55454	HGNCID:	24292	Length:	542	Species:	Homo sapiens

Alignment Length:	580	Identity:	132/580 - (22%)
Similarity:	220/580 - (37%)	Gaps:	161/580 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   300 YVQGL---KAEEMRQESLLLHRDIKRMAKYLEVPDESTYMLPSVSPESDSTKRHFQDHNIL---G 358
            |.|.|   :.|..:..:..|.|.|.::.:.|:              |.....|..|:...:   |
Human    56 YYQALLQEQEEHYQTRATSLKRQIAQLKQELQ--------------EMSEKMRSLQERRNVGANG 106

  Fly   359 ISPELNKFVPASTDDLLDW--------------------------SFIARSLYSASSANPKQKID 397
            |..:.||  ..:..|||::                          ||....::.......:...:
Human   107 IGYQSNK--EQAPSDLLEFLHSQIDKAEVSIGAKLPSEYGVIPFESFTLMKVFQLEMGLTRHPEE 169

  Fly   398 SAMREGLEDAITEV----MENINNYSRQ---------RGRVIEFRE--LLYGYHRLDALHGQDMI 447
            ..:|:...|.:.||    :|.|||....         .|..:.|.|  .:.||:|.:...|....
Human   170 KPVRKDKRDELVEVIEAGLEVINNPDEDDEQEDEEGPLGEKLIFNENDFVEGYYRTERDKGTQYE 234

  Fly   448 LDLLLIYKKYRGKKMTVPVRRHLYVQRAFTGIFVKEVDEDFYNVTLQQSLLGSLFQNGMARLSSH 512
            |..         ||..:...||:.:.|.|                      |.|.:
Human   235 LFF---------KKADLTEYRHVTLFRPF----------------------GPLMK--------- 259

  Fly   513 FTMPSGLLSPTQDKIVFVLPIAGRLGTFERFLRTYERVCVRGEQHCDLLVVIFGSPDELGDHLQL 577
              :.|.::..|:..|..::|:|.|...|.:|::.:..||:..::...|.||.||. :.|.....:
Human   260 --VKSEMIDITRSIINIIVPLAERTEAFVQFMQNFRDVCIHQDKKIHLTVVYFGK-EGLSKVKSI 321

  Fly   578 LHDLHARHVYQQVNWIQRSSAFSRGVALDVAARSSYIRQEDIILFIDVDMVFEVETLQRVRMHTQ 642
            |..:.:...:.....:..:..|:||..|:|.|| ::.:.|.::.|.|||:.|..|.|...|::.:
Human   322 LESVTSESNFHNYTLVSLNEEFNRGRGLNVGAR-AWDKGEVLMFFCDVDIYFSAEFLNSCRLNAE 385

  Fly   643 RGKQVYLPIVFSQYDPQRRSGDAGGSEDEGETPRIDD------ERGYFRQFGFGICAIYKSDILD 701
            .||:|:.|:|||.|:|      |....::...|.::.      :.|::|.||||:...|:||.|
Human   386 PGKKVFYPVVFSLYNP------AIVYANQEVPPPVEQQLVHKKDSGFWRDFGFGMTCQYRSDFL- 443

  Fly   702 EDINGFDKDITGWGLEDVKFLEKIVRVGTRQRGFLANTAELAMDYNEAAEQWRRLSVFRAPDPTL 766
             .|.|||.::.|||.|||....|.:.                          ..|.|.|.|.|.|
Human   444 -TIGGFDMEVKGWGGEDVHLYRKYLH--------------------------GDLIVIRTPVPGL 481

  Fly   767 VHIYHDISCDVQLDAPQYNMCLGTKA------NSLG--------STRLMEQLFHSSPENV 812
            .|::|:..|..:|...||.||:.:||      :.||        .|.|.:|.:.::.|.|
Human   482 FHLWHEKRCADELTPEQYRMCIQSKAMNEASHSHLGMLVFREEIETHLHKQAYRTNSEAV 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9220	NP_001285280.1	Galactosyl_T	71..>251	CDD:304462
CG9220	NP_001285280.1	CHGN	221..799	CDD:283361	127/565 (22%)
CSGALNACT2	NP_061060.3	Glyco_tranf_GTA_type	<122..516	CDD:416254	107/471 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3588
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810