DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9220 and B4galnt3

DIOPT Version :9

Sequence 1:	NP_001285280.1	Gene:	CG9220 / 32497	FlyBaseID:	FBgn0030662	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_942585.1	Gene:	B4galnt3 / 330406	MGIID:	3041155	Length:	986	Species:	Mus musculus

Alignment Length:	793	Identity:	165/793 - (20%)
Similarity:	285/793 - (35%)	Gaps:	247/793 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 KTPADIIGL-----RDE----DTIQNSQRNLVFVGVMTAKSFLEGRARAVYDTWGKEVPGRMAFF 104
            :|.|..:|.     |||    |.::...|:.:|...:.|||.|    |.|.    .:.|.:.::.
Mouse   299 QTAASHVGSSNTPPRDEQPPADMLRPDPRDTLFRVPLIAKSHL----RHVL----PDCPYKPSYL 355

  Fly   105 SSEGSYSDDLPVVGLKNVDDRYPPQKKSFMMLYYMYEHYIDRFEWFIRADDDVYME----PDKLE 165
                  .|.||:       .||  |...|:.|.::|.:...|.......:...|.|    .|: .
Mouse   356 ------VDGLPL-------QRY--QGLRFVHLSFVYPNDYTRLSHMETHNKCFYQESAYDQDR-S 404

  Fly   166 RFLRSIDSSKPQFIGQAGKGNSEEFGLLSLEFDENFCMGGPGVILSSETLRRVAPHIPSCLKNLY 230
            .|...|...||:..|.......|: |||.....|:                 |...||
Mouse   405 SFQEYIKMDKPEKHGPEQPAGLED-GLLEESQYED-----------------VPEEIP------- 444

  Fly   231 STHEDVEVGRCVQK-----FAGIPCTWNYEMQYILRHNSSGRNAYTGKLKRKEIHNAITLHPIKQ 290
             |.:|...|...:|     ..|:..| :|.::.:|..:.||..|...|      .|:.|..|.:.
Mouse   445 -TSQDQNTGIQGRKQKTISTPGLGVT-DYHLRKLLARSQSGPVAPLSK------QNSTTAFPTRT 501

  Fly   291 A----------------------------PLMYRLH----------------SYVQGLKAEEMR- 310
            :                            ||:.|..                :.|:...||:.|
Mouse   502 SNIPVQRPEKSPVPSRDLSHSDQGARRNLPLIQRARPTGDRPGKTLEQSQWLNQVESFIAEQRRG 566

  Fly   311 --------------QESLLLHRDIKRMAKYLEVPDESTYMLPSVSPESDSTKRHFQDHNILGISP 361
                          :|.:::..|.:.     ||.:|.    .....|.|.:
Mouse   567 DRIEPPTPSRGWRPEEDVVIAADQEG-----EVEEEE----EGEDEEEDMS-------------- 608

  Fly   362 ELNKFVPASTDDLLDW--SFIARSL-YSA-----------SSAN---PKQKIDSAMREGLEDAIT 409
            |:.::|| ..|.:::|  :|.|::| :.|           :|.|   |:|       |.||  :|
Mouse   609 EVFEYVP-MFDPVVNWGQTFSAQNLDFQALRTDWIDLNCNTSGNLLLPEQ-------EALE--VT 663

  Fly   410 EV-MENINNYSRQRGRVIEFRELLYGYHRLDALHGQDMILDLLLIYKKYRGKKMTVPVRRHLYVQ 473
            .| :..::  .|.||| .:.:.::....|.|.|.|....|:|.|:    .|:::   ||...||.
Mouse   664 RVFLRKLS--QRTRGR-YQLQRIVNVEKRQDRLRGGRYFLELELL----DGQRL---VRLSEYVS 718

  Fly   474 -RAFTGIFVKEVDEDFYNVTLQQSLLGSLF------------QNGMARLSSHFTMPSGLLSPTQD 525
             |.:.|     .|......|..::|.|.::            |:...:|    ..|.|.....:.
Mouse   719 TRGWRG-----GDHPGREDTEARNLQGLVWSPRNRHRHVLNAQDPEPKL----CWPQGFSWNHRA 774

  Fly   526 KIVFVLPIAGRLGTFERFLRTYERVC-VRGEQHCDLLVVIFGSPDELGDHLQLLHDLHARHVYQQ 589
            .:.|::|:..:....::|:|..|.:. |.|:.|..:::..:.|.| :...:.|     .|...:.
Mouse   775 VVHFIVPVKNQARWVQQFIRDMESLSQVTGDAHFSIIITDYSSED-MDVEMAL-----KRSRLRS 833

  Fly   590 VNWIQRSSAFSRGVALDVAARSSYIRQEDIILFI-DVDMVFEVETLQRVRMHTQRGKQVYLPIVF 653
            ..:::.|..|.|...|.  |....::....|:|: |:.:.|....:..:|.|...||..:.|:|.
Mouse   834 YQYLKLSGNFERSAGLQ--AGIDLVKDPHSIIFLCDLHIHFPAGIIDTIRKHCVEGKMAFAPMVM 896

  Fly   654 SQYDPQRRSGDAGGSEDEGETPRIDDERGYFRQFGFGICAIYKSDILDEDINGFD-KDITG-WGL 716
            ..:.              |.||:..:  ||:...|||:..|||||:  :.|.|.: |:... ||.
Mouse   897 RLHC--------------GATPQWPE--GYWEVNGFGLLGIYKSDL--DKIGGMNTKEFRDRWGG 943

  Fly   717 EDVKFLEKIVRVG 729
            ||.:.|::|::.|
Mouse   944 EDWELLDRILQAG 956

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9220	NP_001285280.1	Galactosyl_T	71..>251	CDD:304462	39/188 (21%)
CG9220	NP_001285280.1	CHGN	221..799	CDD:283361	125/608 (21%)
B4galnt3	NP_942585.1	PA14	143..277	CDD:284994
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	301..324		6/22 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	434..466		8/56 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	481..552		10/76 (13%)
		Glyco_tranf_GTA_type	<776..972	CDD:299700	50/207 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3588
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810