DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9220 and Csgalnact1

DIOPT Version :9

Sequence 1:	NP_001285280.1	Gene:	CG9220 / 32497	FlyBaseID:	FBgn0030662	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_001100779.1	Gene:	Csgalnact1 / 306375	RGDID:	1307618	Length:	530	Species:	Rattus norvegicus

Alignment Length:	610	Identity:	142/610 - (23%)
Similarity:	234/610 - (38%)	Gaps:	171/610 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   257 QYILRHNSSGRNAYTGKLKRK--------------------EIHNAITL------HPIKQAPLMY 295
            |.:|:........|...|||:                    :..:|.:|      .|..||.::.
  Rat    56 QAVLQEREEQHRNYVNSLKRQIAQLKDELQARSEQLRSGQDQASDATSLRSGWDPEPKAQADILA 120

  Fly   296 RLHSYVQGLKAEEMRQESLLLHRDIKRMAKYLEVPDESTYMLPSVSPESDSTKRHFQDHNILGIS 360
            .|...|.  |||        :|..:|...:|..||.:| :.|..|........||
  Rat   121 FLRGQVD--KAE--------VHAGVKLATEYAAVPFDS-FTLQKVYQLETGLTRH---------- 164

  Fly   361 PELNKFVPASTDDLLDWSFIARSLYSASSANPKQK-IDSAMREGLEDAITEVMENINNYSRQRGR 424
                                           |::| :....|:.|.:||...:|::|:
  Rat   165 -------------------------------PEEKPVRKDKRDELVEAIESALESLNS------- 191

  Fly   425 VIEFRELLYGYHRLDALHGQDMILDLLLIYKKYRGKKMTVPVRRHLYVQRAFTGIFVKEVDEDFY 489
            .:|.......|...|.:.|         ||:..|.|..       || :..|.|    :...:|.
  Rat   192 PVESSPHQRPYTAADFIEG---------IYRTERDKGT-------LY-ELTFKG----DHKHEFQ 235

  Fly   490 NVTLQQSLLGSLFQNGMARLSSHFTMPSGLLSPTQDKIVFVLPIAGRLGTFERFLRTYERVCVRG 554
            .:.|.:. .|.:.:....:|:...|:           |..::|:|.|:..|..|::.:..:|::.
  Rat   236 RLVLFRP-FGPIMKVKKEKLNMANTL-----------INVIVPLARRVDKFRHFMQNFREMCIQQ 288

  Fly   555 EQHCDLLVVIFGSPDELGDHLQLLHDLHARHVYQQVNWIQRSSAFSRGVALDVAARSSYIRQEDI 619
            :....|.||.||. :|:.:...:|.:......::...:||.:..||||..|||.||  :.:..::
  Rat   289 DGRVHLTVVYFGK-EEMNEVKGILENTSKAANFRNFTFIQLNGEFSRGKGLDVGAR--FWKGSNV 350

  Fly   620 ILFI-DVDMVFEVETLQRVRMHTQRGKQVYLPIVFSQYDPQRRSGDAGGSEDEGETPRIDD---- 679
            :||. |||:.|..|.|...|::||.||:|:.|::||||:|    |...|..|  ..|.::.
  Rat   351 VLFFCDVDIYFTSEFLNTCRLNTQPGKKVFYPVLFSQYNP----GIIYGHHD--AVPALEQQLVI 409

  Fly   680 --ERGYFRQFGFGICAIYKSDILDEDINGFDKDITGWGLEDVKFLEKIVRVGTRQRGFLANTAEL 742
              |.|::|.||||:...|:||.:  :|.|||.||.|||.|||....|.:.
  Rat   410 KKETGFWRDFGFGMTCQYRSDFI--NIGGFDLDIKGWGGEDVHLYRKYLH--------------- 457

  Fly   743 AMDYNEAAEQWRRLSVFRAPDPTLVHIYHDISCDVQLDAPQYNMCLGTKANSLGSTRLMEQLFHS 807
                       ..|.|.|.|...|.|::|:..|..:|...||.||:.:||        |.:..|.
  Rat   458 -----------SNLIVIRTPVRGLFHLWHEKHCMDELTPEQYRMCMQSKA--------MNEASHG 503

  Fly   808 SPENVQFAADFNRQKQQQQQQQQAR 832
            ....:.|..:.....::|:.:..::
  Rat   504 QLGMLVFRHEIEAHLRKQKLKASSK 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9220	NP_001285280.1	Galactosyl_T	71..>251	CDD:304462
CG9220	NP_001285280.1	CHGN	221..799	CDD:283361	138/575 (24%)
Csgalnact1	NP_001100779.1	Glyco_tranf_GTA_type	68..505	CDD:416254	138/573 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3588
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810