DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9220 and B4GALNT3

DIOPT Version :9

Sequence 1:	NP_001285280.1	Gene:	CG9220 / 32497	FlyBaseID:	FBgn0030662	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_775864.3	Gene:	B4GALNT3 / 283358	HGNCID:	24137	Length:	998	Species:	Homo sapiens

Alignment Length:	396	Identity:	94/396 - (23%)
Similarity:	174/396 - (43%)	Gaps:	75/396 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   362 ELNKFVPASTDDLLDW--SFIARSL--------YSASSANPKQKIDSAMREGLEDAITEV-MENI 415
            |:.::||. .|.:::|  :|.||:|        :...|.|....:....:|.||  :|.| ::.:
Human   620 EVFEYVPV-FDPVVNWDQTFSARNLDFQALRTDWIDLSCNTSGNLLLPEQEALE--VTRVFLKKL 681

  Fly   416 NNYSRQRGRVIEFRELLYGYHRLDALHGQDMILDLLLIYKKYRGKKMTVPVRRHLYVQ-RAFTGI 479
            |  .|.||| .:.:.::....|.|.|.|...:|:|.|:   .:|:::   ||...||. |.:.||
Human   682 N--QRSRGR-YQLQRIVNVEKRQDQLRGGRYLLELELL---EQGQRV---VRLSEYVSARGWQGI 737

  Fly   480 FV---KEVDEDFYNVTLQQSLLGSLFQ---------NGMARLSSHFTMPSGLLSPTQDKIVFVLP 532
            ..   :||:        .::|.|.::.         |..|: ......|.|.....:..:.||:|
Human   738 DPAGGEEVE--------ARNLQGLVWDPHNRRRQVLNTRAQ-EPKLCWPQGFSWSHRAVVHFVVP 793

  Fly   533 IAGRLGTFERFLRTYERVC-VRGEQHCDLLVVIFGSPDELGDHLQLLHDLHARHVYQQVNWIQRS 596
            :..:....::|::..|.:. |.|:.|.::::..:.|.| :...:.|     .|...:...:::.|
Human   794 VKNQARWVQQFIKDMENLFQVTGDPHFNIVITDYSSED-MDVEMAL-----KRSKLRSYQYVKLS 852

  Fly   597 SAFSRGVALDVAARSSYIRQEDIILFI-DVDMVFEVETLQRVRMHTQRGKQVYLPIVFSQYDPQR 660
            ..|.|...|.  |....::....|:|: |:.:.|....:..:|.|...||..:.|:|...:.
Human   853 GNFERSAGLQ--AGIDLVKDPHSIIFLCDLHIHFPAGVIDAIRKHCVEGKMAFAPMVMRLHC--- 912

  Fly   661 RSGDAGGSEDEGETPRIDDERGYFRQFGFGICAIYKSDILDEDINGFD-KDITG-WGLEDVKFLE 723
                       |.||:..:  ||:...|||:..|||||:  :.|.|.: |:... ||.||.:.|:
Human   913 -----------GATPQWPE--GYWEVNGFGLLGIYKSDL--DRIGGMNTKEFRDRWGGEDWELLD 962

  Fly   724 KIVRVG 729
            :|::.|
Human   963 RILQAG 968

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9220	NP_001285280.1	Galactosyl_T	71..>251	CDD:304462
CG9220	NP_001285280.1	CHGN	221..799	CDD:283361	94/396 (24%)
B4GALNT3	NP_775864.3	PA14	143..277	CDD:284994
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	302..326
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	486..562
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	597..616
		Glyco_tranf_GTA_type	<788..984	CDD:299700	50/207 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3588
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810