DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9220 and chsy3

DIOPT Version :9

Sequence 1:	NP_001285280.1	Gene:	CG9220 / 32497	FlyBaseID:	FBgn0030662	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	XP_031748800.1	Gene:	chsy3 / 100494038	XenbaseID:	XB-GENE-980444	Length:	835	Species:	Xenopus tropicalis

Alignment Length:	762	Identity:	309/762 - (40%)
Similarity:	455/762 - (59%)	Gaps:	80/762 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 QNSQRNLVFVGVMTAKSFLEGRARAVYDTWGKEVPGRMAFFSSEGS----YSDDLPVVGLKNVDD 124
            :::..|.::|||||||.:|:.||.|.|.||...:||::.||||:||    ..:.:||:.|..|||
Frog   120 KDTPSNFLYVGVMTAKKYLDTRAVAAYRTWAPYIPGKVEFFSSQGSEEVLLPEPVPVISLPGVDD 184

  Fly   125 RYPPQKKSFMMLYYMYEHYIDRFEWFIRADDDVYMEPDKLERFLRSIDSSKPQFIGQAGKGNSEE 189
            .||||||||||:.||:::|:|::|||:|||||||::.:|||.||||::||||.::||.|.||.||
Frog   185 SYPPQKKSFMMIKYMHDNYLDKYEWFMRADDDVYIKGEKLEEFLRSLNSSKPLYLGQTGLGNIEE 249

  Fly   190 FGLLSLEFDENFCMGGPGVILSSETLRRVAPHIPSCLKNLYSTHEDVEVGRCVQKFAGIPCTWNY 254
            .|.|.||..|||||||||:|.|.|.||::.|||..||:.:|:|||||||||||::|.|..|.|:|
Frog   250 LGKLGLEPGENFCMGGPGMIFSREVLRKMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWSY 314

  Fly   255 EMQYILRHN-SSGRNAYTGKLKRKEIHNAITLHPIKQAPLMYRLHSYVQGLKAEEMRQESLLLHR 318
            |||.:...| ...|..|...|...:||.||||||.|:....||||:|:...|..|:|..::.|||
Frog   315 EMQQLFHENYEHNRKGYIQDLHNSKIHAAITLHPNKRPAYQYRLHNYILSRKISELRYHTIQLHR 379

  Fly   319 DIKRMAKYLEVPDESTYMLPSVSPESDSTKRHFQDHNILGISPELNKFVPASTDDLLDWSFI-AR 382
            :...|:|.               ..|:.:|...|    ||:.|..|:|.|...:::::|.|: .:
Frog   380 ESVLMSKL---------------SNSEISKEDQQ----LGMMPSFNRFQPRERNEVIEWEFLTGK 425

  Fly   383 SLYSASSAN--PKQKIDSAMREGLEDAITEVMENINNYSRQRGRVIEFRELLYGYHRLDALHGQD 445
            .:||. :||  |.|.:.:.::..|:|.:.:|||.||..|:.|||:|:|:|:.|||.|:..|:|.:
Frog   426 HIYSV-NANVPPCQSLTNLLKASLDDTVMQVMEMINENSKSRGRLIDFKEIQYGYRRVHPLYGVE 489

  Fly   446 MILDLLLIYKKYRGKKMTVPVRRHLYVQRAFTGIFVKEVDEDFYNVTLQ----QSLLGSLFQNGM 506
            .|||:||:||:::|:|:|||||||.|:|::|:..|.||.:|......||    .:...|.|.|.:
Frog   490 YILDMLLLYKRHKGRKLTVPVRRHAYLQQSFSKPFFKEEEELDVQSVLQNINTDAQTFSFFSNSL 554

  Fly   507 ARLSS-HFTMPSGLLSPTQDKIVFVLPIAGRLGTFERFLRTYERVCVRGEQHCDLLVVIFG--SP 568
            ...|| |.|  ..:.:.:..||.|::|:.||...|.||:..||:.|:..:|:..|:|::|.  |.
Frog   555 KMFSSLHVT--KEMKANSDKKIHFLVPLTGRFDIFMRFMENYEKTCLIPKQNVKLMVILFNSESS 617

  Fly   569 DELGDHLQLLHDLHARHVYQQVNWIQRSSAFSRGVALDVAARSSYIRQEDIILFIDVDMVFEVET 633
            .:...|.:|:.:...::....:|.|..:..||||::||..  |:....:.::||.|||::|..:.
Frog   618 SDSNMHAELMTEYQNKYPQADMNIITLTGQFSRGLSLDKG--SAQFGNDTLLLFCDVDLMFTSDF 680

  Fly   634 LQRVRMHTQRGKQVYLPIVFSQYDPQRRSGDAGGSEDEGETPR-----IDDERGYFRQFGFGICA 693
            |||.|.:|.:|||||.|||||||||:...|        |..|.     ...:.|::|.:||||..
Frog   681 LQRCRDNTIQGKQVYYPIVFSQYDPKVTYG--------GNPPASNHFVFTKKTGFWRDYGFGITC 737

  Fly   694 IYKSDILDEDINGFDKDITGWGLEDVKFLEKIVRVGTRQRGFLANTAELAMDYNEAAEQWRRLSV 758
            |||||:|  ::.|||..|.|||||||....|::..|                          |..
Frog   738 IYKSDLL--NVGGFDTSIQGWGLEDVDLFNKVINSG--------------------------LKA 774

  Fly   759 FRAPDPTLVHIYHDISCDVQLDAPQYNMCLGTKANSLGSTRLMEQLF 805
            ||:.:..:|||:|.:.||..|:..||.||||:||::..|...:.:::
Frog   775 FRSQETGVVHIFHPVHCDPNLNPKQYKMCLGSKASTFASAAQLAEIW 821

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9220	NP_001285280.1	Galactosyl_T	71..>251	CDD:304462	107/183 (58%)
CG9220	NP_001285280.1	CHGN	221..799	CDD:283361	219/593 (37%)
chsy3	XP_031748800.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	388	1.000	Domainoid score	I794
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	592	1.000	Inparanoid score	I963
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D211685at33208
OrthoFinder	1	1.000	-	-		FOG0002300
OrthoInspector	1	1.000	-	-		otm48565
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2344
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970