DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alp11 and Akp3

DIOPT Version :9

Sequence 1:	NP_573047.1	Gene:	Alp11 / 32496	FlyBaseID:	FBgn0030661	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_073171.2	Gene:	Akp3 / 64621	RGDID:	621650	Length:	558	Species:	Rattus norvegicus

Alignment Length:	509	Identity:	195/509 - (38%)
Similarity:	265/509 - (52%)	Gaps:	74/509 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LALSVPMVEQVQPADELLSSHWLRQAQSQLRERLARTKDSIADVRQAKNVVMLLGDGLSITTLTA 85
            |:|||..||:..||      .|.::|...|  .:|:....|.  ..|||:::.||||:.:.|:||
  Rat    16 LSLSVIPVEEENPA------FWNQKAADAL--NVAKKLQPIQ--TSAKNLIIFLGDGMGVPTVTA 70

  Fly    86 ARILKGQRRGGRGEDAQLAVEQFPFSGLSKTYCIDEQTPDSACTATAYFGGVKTHSGTVGQSGS- 149
            .||||||..|..|.:..||::.||:..|||||.:|.|.||||.|||||..||||:..|:|.|.:
  Rat    71 TRILKGQLEGNLGPETPLAMDHFPYMALSKTYSVDRQVPDSASTATAYLCGVKTNYKTIGVSAAA 135

  Fly   150 ---------GERVDSVLQWAQRAGKATGVVTTTRLTDASPAGAYAHVSRRG------------EE 193
                     |..|.||:..|::|||:.|||||||:..|||||.|.|...|.            :|
  Rat   136 RFDQCNTTFGNEVLSVMYRAKKAGKSVGVVTTTRVQHASPAGTYVHTVNRNWYGDADMPASALQE 200

  Fly   194 --LEIARQLVEEEPGRNLNVILGGGLGKF-----------------ADERRDGKDLLAQWRESNP 239
              .:||.|||.   ..::||||||| .|:                 ...|.|||:|:.:|...:.
  Rat   201 GCKDIATQLVS---NMDINVILGGG-RKYMFPAGTPDPEYPNDVNETGTRLDGKNLVQEWLSKHQ 261

  Fly   240 NGCFSRSLKEL-RNCTDATGT-LLGIFSDSHMSYHLAASKEL-PRLCDMAAAAIEKLERKSQEDG 301
            ...:..:.:|| :...|.:.| |:|:|......:.:.....: |.|.||..||:..|.|..:
  Rat   262 GSQYVWNRQELIQKSLDPSVTYLMGLFEPVDTKFEIQRDPLMDPSLKDMTEAALHVLSRNPK--- 323

  Fly   302 NGYFVFIEGGRIDHGHHETRVGYALDEMVEFDAAVETVIQMTDPRDTLVVVTADHSHTLSMSGYA 366
             |:::|:||||||.|||......||.|.|.||:|:|...|:|..:|||.:|||||||..|..||.
  Rat   324 -GFYLFVEGGRIDRGHHLGTAYLALTEAVMFDSAIERASQLTSEQDTLTIVTADHSHVFSFGGYT 387

  Fly   367 KRGTPILGMDAQQRDVNGVPYSTLNYAIGKWQSLDKDGRRESPSKTLSPTSYTPSY-----IHGR 426
            .|||.|.|: |....::|.||:::.|..|....    |..|.|:.| ...|:.|||     :..:
  Rat   388 LRGTSIFGL-APLNALDGKPYTSILYGNGPGYV----GTGERPNVT-DAESHDPSYQQQAAVPVK 446

  Fly   427 KGVHSGEDVVVFAMGPQSHLFGGVMEQNLLPHIMGYAACLGNGLTLCNQDKDAD 480
            ...|.||||.:||.|||:||..||.|||.:.|:|.:|.|| ...|.|.....||
  Rat   447 SETHGGEDVAIFARGPQAHLLHGVQEQNYIAHVMAFAGCL-EPYTDCGLAPPAD 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alp11	NP_573047.1	ALP_like	68..467	CDD:304875	176/447 (39%)
Akp3	NP_073171.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351421
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48882
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X159
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.860