DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8097 and Rars1

DIOPT Version :9

Sequence 1:	NP_001285279.1	Gene:	CG8097 / 32495	FlyBaseID:	FBgn0030660	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_001099247.2	Gene:	Rars1 / 287191	RGDID:	1309215	Length:	660	Species:	Rattus norvegicus

Alignment Length:	142	Identity:	41/142 - (28%)
Similarity:	70/142 - (49%)	Gaps:	21/142 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   308 ASYILYNSARLEALLRKFNYE---VNNCAYEKLPLLDEIDLSVLEDDVDWELIYG-YLLTFPELM 368
            |:|:||...|:.::.|..|.:   :...|.|...:||.        :.:|:|  | .:|.|||::
  Rat   531 AAYLLYAFTRIRSIARLANIDEEMLQRAARETKIILDH--------EKEWKL--GRCILRFPEIL 585

  Fly   369 ESIMDQLDQGHCGLHLLVHYVENLAAAFSRFYYHKKVLLQKRD--ELMPILYARIYLIKAVRQVL 431
            :.|:|.|     .||.|..|:..||..|:.||.....:.:.|.  :::.:...|:.|.:||..|:
  Rat   586 QKILDDL-----FLHTLCDYIYELATTFTEFYDSCYCVEKDRQTGKVLKVNMWRMLLCEAVAAVM 645

  Fly   432 NTALAVLGIEPV 443
            .....:|||:||
  Rat   646 AKGFDILGIKPV 657

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8097	NP_001285279.1	DALR_1	311..445	CDD:214846	39/139 (28%)
Rars1	NP_001099247.2	Could be involved in the assembly of the multisynthetase complex. /evidence=ECO:0000250	1..72
		Arg_tRNA_synt_N	79..166	CDD:214975
		PLN02286	80..660	CDD:215160	41/142 (29%)
		ArgRS_core	193..457	CDD:185675
		L-arginine binding. /evidence=ECO:0000250\|UniProtKB:P54136	200..202
		'HIGH' region. /evidence=ECO:0000250	201..212
		Anticodon_Ia_like	498..660	CDD:299868	41/142 (29%)
		Interaction with tRNA. /evidence=ECO:0000250\|UniProtKB:Q05506	529..543		5/11 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0018
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810