Protein Alignment CG9215 and ZNF616

DIOPT Version :10

• Sequence 1: NP_573045.1
• Gene: CG9215 / 32494
• FlyBaseID: FBgn0030659
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_848618.2
• Gene: ZNF616 / 90317
• HGNCID: 28062
• Length: 781
• Species: Homo sapiens
• Alignment Length: 334
• Identity: 93/334 - (27%)
• Similarity: 128/334 - (38%)
• Gaps: 81/334 - (24%)

  Fly   222 ELDPWDDENTPE-------------------------HLYEIETPLIEESVVASPPLPLPPTHPA 261
            ||.|.::.||.|                         ||:::|... ::.......:|:|  |..
Human    56 ELPPTENSNTGERFQTVALERHQSYDIENLYFREIQKHLHDLEFQW-KDGETNDKEVPVP--HEN 117

  Fly   262 NQQKKRTYRR---VSPNVKHEKLTANVDDD-------------FKAGSTTKRRN--CERSPKI-- 306
            |...||....   |..|....:||:|.:..             ::...|.|..|  |..||.|
Human   118 NLTGKRDQHSQGDVENNHIENQLTSNFESRLAELQKVQTEGRLYECNETEKTGNNGCLVSPHIRE 182

  Fly   307 ----CDVCGNTYKYQHALNAHMRRHNNERP----------------------------YSCEVCQ 339
                |:.||..:|...:|..|.|.|..|:|                            |.|:||.
Human   183 KTYVCNECGKAFKASSSLINHQRIHTTEKPYKCNECGKAFHRASLLTVHKVVHTRGKSYQCDVCG 247

  Fly   340 KAFISNVELRRHMRVHTGQKPYSCRHCERRFSDFGSSKKHERIHTGERPYVCEVCNKGFAYAHVL 404
            |.|..|....||.|.|||||||.|..|.:.||.......|:||||||:||.|.:|.|.|:....|
Human   248 KIFRKNSYFVRHQRSHTGQKPYICNECGKSFSKSSHLAVHQRIHTGEKPYKCNLCGKSFSQRVHL 312

  Fly   405 SAHRRTHTGKKQFQCTQCDKGFTKKTYLSAHMEQHRGSGNGEASVASSSADASSRNQNASARKES 469
            ..|:..|||::.|:|.:|.|.|.:.:.|:.|...|.|....:..|...:....| |.....|..|
Human   313 RLHQTVHTGERPFKCNECGKTFKRSSNLTVHQVIHAGKKPYKCDVCGKAFRHRS-NLVCHRRIHS 376

  Fly   470 ARKQQQIPE 478
            ..||.:..|
Human   377 GEKQYKCNE 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9215	NP_573045.1	zf-AD	16..92	CDD:462262
		COG5048	<303..439	CDD:227381	59/169 (35%)
		C2H2 Zn finger	307..327	CDD:275368	7/19 (37%)
		C2H2 Zn finger	335..355	CDD:275368	9/19 (47%)
		zf-H2C2_2	347..371	CDD:463886	12/23 (52%)
		C2H2 Zn finger	363..383	CDD:275368	6/19 (32%)
		C2H2 Zn finger	391..411	CDD:275368	6/19 (32%)
		C2H2 Zn finger	419..439	CDD:275368	6/19 (32%)
ZNF616	NP_848618.2	KRAB	7..47	CDD:460171
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	105..129		6/25 (24%)
		SUF4-like	187..>231	CDD:411020	10/43 (23%)
		C2H2 Zn finger	187..208	CDD:411020	7/20 (35%)
		C2H2 Zn finger	187..207	CDD:275368	7/19 (37%)
		C2H2 Zn finger	243..263	CDD:275368	9/19 (47%)
		COG5048	266..707	CDD:227381	43/121 (36%)
		C2H2 Zn finger	271..291	CDD:275368	6/19 (32%)
		C2H2 Zn finger	299..319	CDD:275368	6/19 (32%)
		C2H2 Zn finger	327..347	CDD:275368	6/19 (32%)
		C2H2 Zn finger	355..375	CDD:275368	4/20 (20%)
		C2H2 Zn finger	383..403	CDD:275368	1/3 (33%)
		C2H2 Zn finger	411..431	CDD:275368
		C2H2 Zn finger	439..459	CDD:275368
		C2H2 Zn finger	467..487	CDD:275368
		C2H2 Zn finger	495..515	CDD:275368
		C2H2 Zn finger	523..543	CDD:275368
		C2H2 Zn finger	551..571	CDD:275368
		C2H2 Zn finger	579..599	CDD:275368
		C2H2 Zn finger	607..627	CDD:275368
		C2H2 Zn finger	635..655	CDD:275368
		C2H2 Zn finger	663..683	CDD:275368
		C2H2 Zn finger	691..711	CDD:275368
		zf-H2C2_2	703..726	CDD:463886
		C2H2 Zn finger	719..739	CDD:275368
		zf-H2C2_2	731..756	CDD:463886
		C2H2 Zn finger	747..767	CDD:275368