Protein Alignment CG9215 and Ctcf

DIOPT Version :10

• Sequence 1: NP_573045.1
• Gene: CG9215 / 32494
• FlyBaseID: FBgn0030659
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: XP_006255598.1
• Gene: Ctcf / 83726
• RGDID: 621344
• Length: 738
• Species: Rattus norvegicus
• Alignment Length: 597
• Identity: 119/597 - (19%)
• Similarity: 193/597 - (32%)
• Gaps: 244/597 - (40%)

  Fly   111 APPAPMLVDKQQ---------EQLKL---DLEQAHVRLPATLKIRRLNVEPCSSSSVSGTITTST 163
            ||.|...||..|         |:..:   :|:...|.:|.|:.:...:||....:
  Rat    83 APEAEAAVDDTQIITLQVVNMEEQPINIGELQLVQVPVPVTVPVATTSVEELQGA---------- 137

  Fly   164 EPSEDVKEEKTDSLSLI------PDGAMVLSLNDFQAQDSITQQAE---EKDPKKQQDED----- 214
            ..:|..||...:|..:|      |:|..|:.:. ...:....:|.|   ::||..|:|.|
  Rat   138 YENEVSKEGLAESEPMICHTLPLPEGFQVVKVG-ANGEVETLEQGELPPQEDPSWQKDPDYQPPA 201

  Fly   215 ---------------EGQAKMLELDPWDDENTPEHLYEIETPLIEESVVAS--PPLPLPPTHPAN 262
                           ||:...:.:..:::|.....|.|:..    |.||.:  ||   .||....
  Rat   202 KKTKKTKKSKLRYTEEGKDVDVSVYDFEEEQQEGLLSEVNA----EKVVGNMKPP---KPTKIKK 259

  Fly   263 QQKKRTY----------RRVSPNVKHEKLTANVDDDFKAGSTTKRRNCERSPKICDVCG------ 311
            :..|:|:          ||           :|:|...|:       :.:..|..|.:||
  Rat   260 KGVKKTFQCELCSYTCPRR-----------SNLDRHMKS-------HTDERPHKCHLCGRAFRTV 306

  Fly   312 -------NT---------------------------YKYQH-----------------ALNAHMR 325
                   ||                           ||:.|                 .|..|:|
  Rat   307 TLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDYASVEVSKLKRHIR 371

  Fly   326 RHNNERPYSCEVCQKAFISNVELRRHMRVHTGQKPYSCRHCERRFSDFGSSK------------- 377
            .|..|||:.|.:|..|.....:|:||||.|:|:|||.|..|..||:..|:.|
  Rat   372 SHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQSGTMKMHILQKHTENVAK 436

  Fly   378 -----------------------------------------------KHERIHTGERPYVCEVCN 395
                                                           :|::.|..|:.:.|:.|:
  Rat   437 FHCPHCDTVIARKSDLGVHLRKQHSYIEQGKKCRYCDAVFHERYALIQHQKSHKNEKRFKCDQCD 501

  Fly   396 KGFAYAHVLSAHRRTHTGKKQFQCTQCDKGFTKKTYLSAHMEQHRGSGNGEASVASSSADASSRN 460
            ........:..|:|||||:|.:.|:.|||.|.:|..|..|.:::.......|:...|....:...
  Rat   502 YACRQERHMIMHKRTHTGEKPYACSHCDKTFRQKQLLDMHFKRYHDPNFVPAAFVCSKCGKTFTR 566

  Fly   461 QNASAR-------------------KESARKQQQIPESFSLDSVELEQTKVLEECIVANDFMFNE 506
            :|..||                   |:|.|.:::...|...||.:                   .
  Rat   567 RNTMARHADNCAGPDGVEGENGGETKKSKRGRKRKMRSKKEDSSD-------------------S 612

  Fly   507 EDNAEQEANDRE 518
            |:|||.:.:|.|
  Rat   613 EENAEPDLDDNE 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9215	NP_573045.1	zf-AD	16..92	CDD:462262
		COG5048	<303..439	CDD:227381	55/252 (22%)
		C2H2 Zn finger	307..327	CDD:275368	11/76 (14%)
		C2H2 Zn finger	335..355	CDD:275368	8/19 (42%)
		zf-H2C2_2	347..371	CDD:463886	13/23 (57%)
		C2H2 Zn finger	363..383	CDD:275368	7/79 (9%)
		C2H2 Zn finger	391..411	CDD:275368	4/19 (21%)
		C2H2 Zn finger	419..439	CDD:275368	8/19 (42%)
Ctcf	XP_006255598.1	zf-H2C2_5	266..289	CDD:404746	5/40 (13%)
		C2H2 Zn finger	268..288	CDD:275368	5/37 (14%)
		zf-H2C2_2	280..305	CDD:463886	7/31 (23%)
		C2H2 Zn finger	296..316	CDD:275368	4/19 (21%)
		zf-H2C2_2	309..333	CDD:463886	2/23 (9%)
		C2H2 Zn finger	324..347	CDD:275368	2/22 (9%)
		zf-H2C2_5	351..375	CDD:404746	4/23 (17%)
		C2H2 Zn finger	353..373	CDD:275368	3/19 (16%)
		COG5048	<366..500	CDD:227381	30/133 (23%)
		C2H2 Zn finger	381..401	CDD:275368	8/19 (42%)
		C2H2 Zn finger	409..426	CDD:275368	6/16 (38%)
		C2H2 Zn finger	439..457	CDD:275368	0/17 (0%)
		C2H2 Zn finger	469..489	CDD:275368	1/19 (5%)
		C2H2 Zn finger	497..517	CDD:275368	4/19 (21%)
		zf-H2C2_2	509..534	CDD:463886	12/24 (50%)
		C2H2 Zn finger	525..546	CDD:275368	8/20 (40%)
		C2H2 Zn finger	557..573	CDD:275368	3/15 (20%)