Protein Alignment CG9215 and ZBTB17

DIOPT Version :10

• Sequence 1: NP_573045.1
• Gene: CG9215 / 32494
• FlyBaseID: FBgn0030659
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001274532.1
• Gene: ZBTB17 / 7709
• HGNCID: 12936
• Length: 810
• Species: Homo sapiens
• Alignment Length: 629
• Identity: 141/629 - (22%)
• Similarity: 217/629 - (34%)
• Gaps: 229/629 - (36%)

  Fly    85 CTAVQKLFRSASRSTSTSAVFAAAAAAPPAPMLVDKQQEQLKLDLEQAHVRLPATLKIRRLNVEP 149
            |.|::.|...|:.....:...|....        ||:.::.|:          ||..:.||  |.
Human   108 CHALKSLAEPATSPGGNAEALATEGG--------DKRAKEEKV----------ATSTLSRL--EQ 152

  Fly   150 CSSSSVSGTITTSTEPSEDVKE----------------EKTDS------LSLIPDGAMVLSLNDF 192
            ...|:..|       ||.|:||                ||.|:      :.|.||....::..:.
Human   153 AGRSTPIG-------PSRDLKEERGGQAQSAASGAEQTEKADAPREPPPVELKPDPTSGMAAAEA 210

  Fly   193 QA--QDSITQ----------QAEEKDPKKQQDEDEGQAKMLE----LD----PWDDENTPEHLYE 237
            :|  .:|..|          :.|:|:.::|::|..|.|::.|    |:    |.::||
Human   211 EAALSESSEQEMEVEPARKGEEEQKEQEEQEEEGAGPAEVKEEGSQLENGEAPEENEN------- 268

  Fly   238 IETPLIEESVVASPPLPLPPTHPANQQKKRTYRRVSPNVKHEKLTANVDD---DFKAGSTTKR-- 297
                  |||........|  ...|...:..||...:.:..:..:....:|   :|......||
Human   269 ------EESAGTDSGQEL--GSEARGLRSGTYGDRTESKAYGSVIHKCEDCGKEFTHTGNFKRHI 325

  Fly   298 -----------RNCERS------------------PKICDVCGNTYKYQHALNAHMRRHNNERPY 333
                       |.|.::                  |..|:.||.:|:....||.|.:||:.|..|
Human   326 RIHTGEKPFSCRECSKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARY 390

  Fly   334 SCEVCQKAFISNVELRRHMRVHTGQKPYSCRHCERRFSD-------------------------- 372
            .||.|.|.|.::..|:||..||:|:|||.|.:|.|.|||
Human   391 RCEDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKF 455

  Fly   373 ------------------------------FGSSKKHERIHTGERPYVCEVCNKGFAYAHVLSAH 407
                                          .|:.|:|.|||:||:||||..|.:.||....|..|
Human   456 NQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCIHCQRQFADPGALQRH 520

  Fly   408 RRTHTGKKQFQCTQCDKGFTKKTYLSAHMEQHRGSGN------GEASVASSS-ADASSRNQNASA 465
            .|.|||:|..||..|.|.||:.:.|.||:.||.|...      |:..|.||. |:....:.|...
Human   521 VRIHTGEKPCQCVMCGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRP 585

  Fly   466 RKESARKQQQIPESFSLDSVELEQTKVLEECIVANDFMFNEEDNAEQEANDREGLQHDDSYPYV- 529
            .|                            |.|.:....|..|.:      :..:.|....||:
Human   586 HK----------------------------CSVCSKAFVNVGDLS------KHIIIHTGEKPYLC 616

  Fly   530 ----GGYQSVDSVKELVG---------DLLDTEEFCDESKYMIE 560
                .|:..||:::..|.         .:|:.||..:.|...::
Human   617 DKCGRGFNRVDNLRSHVKTVHQGKAGIKILEPEEGSEVSVVTVD 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9215	NP_573045.1	zf-AD	16..92	CDD:462262	2/6 (33%)
		COG5048	<303..439	CDD:227381	63/209 (30%)
		C2H2 Zn finger	307..327	CDD:275368	7/19 (37%)
		C2H2 Zn finger	335..355	CDD:275368	8/19 (42%)
		zf-H2C2_2	347..371	CDD:463886	12/23 (52%)
		C2H2 Zn finger	363..383	CDD:275368	10/75 (13%)
		C2H2 Zn finger	391..411	CDD:275368	7/19 (37%)
		C2H2 Zn finger	419..439	CDD:275368	8/19 (42%)
ZBTB17	NP_001274532.1	BTB_POZ_ZBTB17_MIZ1	2..113	CDD:349515	2/4 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..295		44/220 (20%)
		Interaction with MYC	269..308		7/40 (18%)
		COG5048	306..637	CDD:227381	90/364 (25%)
		C2H2 Zn finger	308..328	CDD:275368	4/19 (21%)
		C2H2 Zn finger	336..356	CDD:275368	2/19 (11%)
		C2H2 Zn finger	364..384	CDD:275368	7/19 (37%)
		C2H2 Zn finger	392..412	CDD:275368	8/19 (42%)
		C2H2 Zn finger	420..440	CDD:275368	6/19 (32%)
		C2H2 Zn finger	448..468	CDD:275368	0/19 (0%)
		C2H2 Zn finger	476..496	CDD:275368	4/19 (21%)
		C2H2 Zn finger	504..524	CDD:275368	7/19 (37%)
		C2H2 Zn finger	532..552	CDD:275368	8/19 (42%)
		C2H2 Zn finger	560..580	CDD:275368	5/19 (26%)
		C2H2 Zn finger	588..608	CDD:275368	4/25 (16%)
		C2H2 Zn finger	616..635	CDD:275370	4/18 (22%)
		C2H2 Zn finger	726..746	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	786..810