DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9215 and gzf1

DIOPT Version :9

Sequence 1:	NP_573045.1	Gene:	CG9215 / 32494	FlyBaseID:	FBgn0030659	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_001039101.1	Gene:	gzf1 / 733920	XenbaseID:	XB-GENE-1020991	Length:	697	Species:	Xenopus tropicalis

Alignment Length:	522	Identity:	114/522 - (21%)
Similarity:	189/522 - (36%)	Gaps:	145/522 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 NVEPCSSSSVSGTITTSTEPSEDVKEEKTDSLSLIPDGAMVLSLND------FQAQDSITQQAEE 204
            :::|...:.::|..:...||:     :.||...|..|..:..:::.      |.|.:..|::.:|
Frog   152 DIDPLQLNPLTGLQSPMAEPT-----QITDPTPLFTDSTVGQNMDQACVDTAFIATEENTEKKKE 211

  Fly   205 ------KDPKKQQDEDEGQAKMLELDPWDDENTPEHLYEIETPLIEESVVASPPLPLPPTH---- 259
                  ..||:......|:..::|:        |:..|   |..:.|....:...|:...:
Frog   212 ALKKPQAKPKRSTGRVSGKKAVVEI--------PKKKY---TRKLREQQNIAQTRPIENGNDGVQ 265

  Fly   260 -PANQQKKRTYRRVSPNVKHEKLTANVD---DDFKAGSTTKRRNCERSPKI-------------- 306
             |:|.|       .:.....:.:.|..|   :|.::.....:.|.::|..:
Frog   266 VPSNMQ-------TADEQSEDSVKAEDDSHCEDSESYKNGDQDNNDQSANMVSCPVCGKSFADEK 323

  Fly   307 ------------------CDVCGNTYKYQHALNAHMRR-HNNERPYSCEVCQKAFISNVELRRHM 352
                              ||:|..|:..:..|.:|.|. |:|||.:.||:|.|.|....:::||:
Frog   324 SFLKHSKQEHLDSEIVFRCDICSQTFANRCNLKSHQRHVHSNERRFPCELCGKKFKRKKDIKRHI 388

  Fly   353 ------------------------------RVHTGQKPYSCRHCERRFSDFGSSKKHERIHTGER 387
                                          |.|||.||:||.||:.:||...:.|.|.|.||||:
Frog   389 IQVHEGGRERHFCKLCGKGLSSKTSLSLHERTHTGDKPFSCPHCQAKFSQTSALKTHLRTHTGEK 453

  Fly   388 PYVCEVCNKGFAYAHVLSAHRRTHTGKKQFQCTQCDKGFTKKTYLSAHMEQHRGS---------- 442
            |:||:.|:..|...|:|..|:|.|||:|.|.|..|.|.|..|.||..|...|.||
Frog   454 PFVCDECDARFTQNHMLIYHKRCHTGEKPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCDFCCR 518

  Fly   443 --------------GNGEASVASSSADASSRNQNASARKESARKQQQ------IPESFSLDSVEL 487
                          ..||...............||..|.......::      ...:|:..|...
Frog   519 TFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQLNALQRHHRIHTGEKPFMCSACQRTFTDQSTLR 583

  Fly   488 EQTKVLEECIVANDFMF----NEEDNAEQEANDREGLQHDD----SYPYVGGYQSVDSVKELVGD 544
            ..|.:.::......|:.    ..:|..::....||.|.:..    :||..|.||::..|...| |
Frog   584 RHTSIHDKNTPWKSFLVVLDPASKDEGQKSEEGREDLPNPGADKLTYPENGHYQNLTVVPGTV-D 647

  Fly   545 LL 546
            ||
Frog   648 LL 649

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9215	NP_573045.1	zf-AD	16..92	CDD:285071
		DUF2117	165..>273	CDD:303038	21/124 (17%)
		COG5048	<303..439	CDD:227381	60/198 (30%)
		C2H2 Zn finger	307..327	CDD:275368	7/20 (35%)
		zf-H2C2_2	319..344	CDD:290200	12/25 (48%)
		zf-C2H2	333..355	CDD:278523	8/51 (16%)
		C2H2 Zn finger	335..355	CDD:275368	8/49 (16%)
		zf-H2C2_2	347..371	CDD:290200	12/53 (23%)
		C2H2 Zn finger	363..383	CDD:275368	8/19 (42%)
		zf-H2C2_2	375..400	CDD:290200	12/24 (50%)
		C2H2 Zn finger	391..411	CDD:275368	7/19 (37%)
		zf-H2C2_2	404..427	CDD:290200	11/22 (50%)
		C2H2 Zn finger	419..439	CDD:275368	8/19 (42%)
gzf1	NP_001039101.1	BTB	21..125	CDD:279045
		BTB	32..133	CDD:197585
		C2H2 Zn finger	312..333	CDD:275368	0/20 (0%)
		C2H2 Zn finger	342..363	CDD:275368	7/20 (35%)
		C2H2 Zn finger	401..421	CDD:275368	1/19 (5%)
		zf-H2C2_2	413..438	CDD:290200	11/24 (46%)
		zf-C2H2_8	426..532	CDD:292531	39/105 (37%)
		C2H2 Zn finger	429..449	CDD:275368	8/19 (42%)
		zf-H2C2_2	441..466	CDD:290200	12/24 (50%)
		C2H2 Zn finger	457..477	CDD:275368	7/19 (37%)
		zf-H2C2_2	469..494	CDD:290200	12/24 (50%)
		C2H2 Zn finger	485..505	CDD:275368	8/19 (42%)
		zf-H2C2_2	497..522	CDD:290200	6/24 (25%)
		C2H2 Zn finger	513..533	CDD:275368	0/19 (0%)
		zf-H2C2_2	525..550	CDD:290200	2/24 (8%)
		COG5048	537..>594	CDD:227381	6/56 (11%)
		C2H2 Zn finger	541..561	CDD:275368	3/19 (16%)
		zf-H2C2_2	553..577	CDD:290200	2/23 (9%)
		C2H2 Zn finger	569..589	CDD:275368	3/19 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000