DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9215 and CG18764

DIOPT Version :9

Sequence 1:	NP_573045.1	Gene:	CG9215 / 32494	FlyBaseID:	FBgn0030659	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_652712.2	Gene:	CG18764 / 59239	FlyBaseID:	FBgn0042205	Length:	409	Species:	Drosophila melanogaster

Alignment Length:	448	Identity:	111/448 - (24%)
Similarity:	174/448 - (38%)	Gaps:	81/448 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LGVACLVCLAEEPEASSIYGHDPES----PHMLILDKIRCCTSLQLDSSPSQLQRWPDKICKQCH 72
            :.:.|..|      .|.||...|::    .:..:|..|...|...|.:.|    ..|..||..|.
  Fly     1 MALQCRTC------GSIIYNKMPKNLFHIENEKMLQDINLVTGTTLHNDP----ELPSSICACCT 55

  Fly    73 LELSVSYRFHEKCTAVQK--LFRSASRSTSTSAVFAAAAAAPPAPMLVDKQQEQLKLDLEQAHVR 135
            |:|:.:..|.|:|...||  :.|..|......|......|:||
  Fly    56 LDLNQAILFRERCILTQKQLVHRRRSPEAKEPAEDVEEMASPP---------------------- 98

  Fly   136 LPATLKIRRLNVEPCSSSSVSGTITTSTEPSEDVKEEKTDSLSLIPDGAMVLSLNDFQAQDSITQ 200
                         .|.:...........|..|:|.:..:|:...:.:...:.|:.|..|...:.:
  Fly    99 -------------DCLNDPFGEVDEYIVESPEEVLDHDSDAHHDLDEDNYIDSVEDVDALQDMAE 150

  Fly   201 QAEEKDPKKQQDEDEGQAKMLELDPWDDENT-------PEHLYEIETPLIEESVVASPPLPLP-- 256
            .||| |.:..:.......|.||....||.|:       |::.......:.|..|.::|..|||
  Fly   151 VAEE-DSQDVESLISSVQKELESICNDDSNSDNNDYMEPQNGSYFNETINEYEVSSNPNTPLPES 214

  Fly   257 ------PTHPANQQKKRTYRRVS-PNVKHEKLTANVDDDFKAGSTTKRRNCERSPKICDVCGNTY 314
                  .|.||..:.||..:.|: .|:..|::       .:.....::|.|     :|:.||..:
  Fly   215 KSAAGRSTKPATTKPKRKKQYVTWKNMTEEQI-------IERKRLQRKREC-----VCEQCGRQF 267

  Fly   315 KYQHALNAHMRRHNNERPYSCEVCQKAFISNVELRRHMR-VHTGQKPYSCRHCERRFSDFGSSKK 378
            ..|.....||.||...:.::|:.|.|.|.::..:..|.| :|.|:|||.||.|.:.|.:..:...
  Fly   268 TDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMTLHQRIIHQGEKPYDCRFCTKSFHNSNTRLI 332

  Fly   379 HERIHTGERPYVCEVCNKGFAYAHVLSAHRRTHTGKKQFQCTQCDKGFTKKTYLSAHM 436
            |||.||..:||.|..|:|.|..|.....|...|||.:.|.||.|.:.|.:.|:|.||:
  Fly   333 HERTHTNAKPYSCHHCDKCFKSASGRKRHELIHTGVRAFACTICKQSFQRNTHLKAHL 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9215	NP_573045.1	zf-AD	16..92	CDD:285071	22/81 (27%)
		DUF2117	165..>273	CDD:303038	28/122 (23%)
		COG5048	<303..439	CDD:227381	48/135 (36%)
		C2H2 Zn finger	307..327	CDD:275368	6/19 (32%)
		zf-H2C2_2	319..344	CDD:290200	8/24 (33%)
		zf-C2H2	333..355	CDD:278523	6/22 (27%)
		C2H2 Zn finger	335..355	CDD:275368	6/20 (30%)
		zf-H2C2_2	347..371	CDD:290200	10/24 (42%)
		C2H2 Zn finger	363..383	CDD:275368	7/19 (37%)
		zf-H2C2_2	375..400	CDD:290200	11/24 (46%)
		C2H2 Zn finger	391..411	CDD:275368	6/19 (32%)
		zf-H2C2_2	404..427	CDD:290200	8/22 (36%)
		C2H2 Zn finger	419..439	CDD:275368	8/18 (44%)
CG18764	NP_652712.2	zf-AD	4..75	CDD:214871	22/80 (28%)
		C2H2 Zn finger	260..280	CDD:275368	6/19 (32%)
		zf-H2C2_2	272..297	CDD:290200	8/24 (33%)
		C2H2 Zn finger	288..309	CDD:275368	6/20 (30%)
		C2H2 Zn finger	317..337	CDD:275368	7/19 (37%)
		C2H2 Zn finger	345..365	CDD:275368	6/19 (32%)
		C2H2 Zn finger	373..391	CDD:275368	8/18 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960