DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9215 and CG6654

DIOPT Version :9

Sequence 1:	NP_573045.1	Gene:	CG9215 / 32494	FlyBaseID:	FBgn0030659	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_650429.1	Gene:	CG6654 / 41831	FlyBaseID:	FBgn0038301	Length:	639	Species:	Drosophila melanogaster

Alignment Length:	596	Identity:	138/596 - (23%)
Similarity:	216/596 - (36%)	Gaps:	184/596 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VDLGVACLVCLAEEPEASSIYGHDPESPHMLILDKIRCCTSLQLDSSPSQLQRWPDKICKQCHLE 74
            :|:...||.||:......|||.....|   .:.|.||..|.    :.|.:....|:|:|..|..|
  Fly     1 MDVDKICLTCLSSTGPLLSIYDGGSGS---CLADMIREFTK----TKPRRNDNLPEKVCLSCLSE 58

  Fly    75 LSVSYRFHEKC----TAVQKLFRSASRSTSTSAVFAAAAAAPPAPMLVDKQQEQLKLDLEQAHVR 135
            :|..|.|..||    ..:::|..:|......|.|   :.:.|.|......|....:.|...|.|:
  Fly    59 ISNCYTFKIKCENSSRTLRQLLPNALPEEPDSKV---SISCPVATTDQAVQTTSWEPDRCTASVQ 120

  Fly   136 LPATLKIRRLNVEPCSSSSVSGTITTSTE------------PSEDVKEEKTDSLSLIPDGAMVLS 188
            ..|   :...:.|. ::|.:..||:...:            |.|.|  |||.||.|...|    :
  Fly   121 TDA---VTTTDAEQ-NTSLIKSTISVDLDYEGEGEVFDYELPDEPV--EKTTSLILQVQG----N 175

  Fly   189 LNDFQ----AQDSITQQAEEKDPKKQ------------QDEDE-------------GQAKMLELD 224
            |.|.:    .|.::..:.::.:.::|            .:|.|             ..||:|...
  Fly   176 LKDEKEVVFTQTNVIYEGDDHELEQQIRECNLAIFEGVDNEAEIITVTAPQVTTRKSAAKLLTQQ 240

  Fly   225 PWDDENTP----EHLYEIETP--------------LIEESVVASPPL---PLPPTHPANQQKKRT 268
            ..|...||    |...|:|..              ::::.|.|:||.   |.|..|....|:|.:
  Fly   241 ENDKHQTPVGSKEEARELEKEQVPQSAKRTSRRRGVVKQDVPATPPSDAEPSPKQHRLGTQRKLS 305

  Fly   269 YRR--------------VSPNVK------------------HEKLTANVDDDFKAGSTTK----- 296
            ..|              .:|.:|                  |.:....::.::|.....|
  Fly   306 APRAGTVNGPSTTSGAATTPELKYHCDRCNAGFAVEKSLMIHRRQKGCINRNYKCNECEKVFVSP 370

  Fly   297 ------------------------------------RRN-------CER---------------- 302
                                                :||       |::
  Fly   371 DHLAEHQASHGAHNCPECGIRCDSKEALSKHMVQGHKRNLRNQCNICQKVFTMLSTLRDHMRIHT 435

  Fly   303 --SPKICDVCGNTYKYQHALNAHMRRHNNERPYSCEVCQKAFISNVELRRHMRVHTGQKPYSCRH 365
              .|.:|::||.::.....|..|..||:..:.:.||:|..:|::..||..|.|.|||.||:.|..
  Fly   436 GEKPFVCNICGKSFTQNANLRQHKLRHSETKSFKCELCPHSFVTKAELTSHARTHTGDKPFECEV 500

  Fly   366 CERRFSDFGSSKKHERIHTGERPYVCEVCNKGFAYAHVLSAHRRTHTGKKQFQCTQCDKGFTKKT 430
            |..||:...|..||:|.|||||||.|::|...|...:||..|||||||::.:.|..|.|.||::.
  Fly   501 CLARFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQRG 565

  Fly   431 YLSAHMEQHRG 441
            ....|...|:|
  Fly   566 DCQMHQRTHQG 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9215	NP_573045.1	zf-AD	16..92	CDD:285071	23/79 (29%)
		DUF2117	165..>273	CDD:303038	35/171 (20%)
		COG5048	<303..439	CDD:227381	54/135 (40%)
		C2H2 Zn finger	307..327	CDD:275368	5/19 (26%)
		zf-H2C2_2	319..344	CDD:290200	8/24 (33%)
		zf-C2H2	333..355	CDD:278523	8/21 (38%)
		C2H2 Zn finger	335..355	CDD:275368	8/19 (42%)
		zf-H2C2_2	347..371	CDD:290200	12/23 (52%)
		C2H2 Zn finger	363..383	CDD:275368	8/19 (42%)
		zf-H2C2_2	375..400	CDD:290200	14/24 (58%)
		C2H2 Zn finger	391..411	CDD:275368	8/19 (42%)
		zf-H2C2_2	404..427	CDD:290200	11/22 (50%)
		C2H2 Zn finger	419..439	CDD:275368	6/19 (32%)
CG6654	NP_650429.1	zf-AD	6..79	CDD:285071	23/79 (29%)
		C2H2 Zn finger	331..354	CDD:275368	1/22 (5%)
		COG5048	<357..570	CDD:227381	58/212 (27%)
		C2H2 Zn finger	360..380	CDD:275368	1/19 (5%)
		C2H2 Zn finger	385..406	CDD:275370	0/20 (0%)
		C2H2 Zn finger	414..434	CDD:275368	1/19 (5%)
		zf-H2C2_2	427..451	CDD:290200	4/23 (17%)
		C2H2 Zn finger	442..490	CDD:275368	15/47 (32%)
		C2H2 Zn finger	470..487	CDD:275368	6/16 (38%)
		zf-H2C2_2	482..507	CDD:290200	13/24 (54%)
		C2H2 Zn finger	498..518	CDD:275368	8/19 (42%)
		zf-H2C2_2	510..534	CDD:290200	13/23 (57%)
		C2H2 Zn finger	526..546	CDD:275368	8/19 (42%)
		zf-H2C2_2	539..563	CDD:290200	12/23 (52%)
		C2H2 Zn finger	554..574	CDD:275368	6/19 (32%)
		C2H2 Zn finger	582..602	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960