DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9215 and CG17385

DIOPT Version :9

Sequence 1:	NP_573045.1	Gene:	CG9215 / 32494	FlyBaseID:	FBgn0030659	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_001286418.1	Gene:	CG17385 / 36603	FlyBaseID:	FBgn0033934	Length:	278	Species:	Drosophila melanogaster

Alignment Length:	309	Identity:	87/309 - (28%)
Similarity:	139/309 - (44%)	Gaps:	63/309 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   276 VKHEKLTAN------VDDDF--KAGSTTKRR---NCERSPKICDVCGNTYKYQHALNAHMRRHNN 329
            |:.::..||      .|..|  |...|..|:   |..::...|.:|..::.....|:.||:.||:
  Fly     6 VEFDETVANQFSCKRCDRTFRSKRDQTLHRQEVHNHNKTTYECKLCAKSFCNSGNLDRHMKVHND 70

  Fly   330 ERPYSCEVCQKAFISNVELRRHMRVHTGQKPYSCRHCERRFSDFGSSKKHERIHTGERPYVCEVC 394
            .||:.|.:|.|||...|.|:||..||:|::|::|..|.:.|:...:.|:|:..||||:|:.|:.|
  Fly    71 VRPFVCNICSKAFAQAVNLQRHYAVHSGERPFTCNFCNKSFTQQSNMKRHKMTHTGEKPFRCQRC 135

  Fly   395 NKGFAYAHVLSAHRRTHTGKKQFQCTQCDKGFTKKTYLSAHMEQHRGSG---NGEASVASSSADA 456
            .:.|:....|..|:..|...|.:||..|:||||:.:....|::.|...|   :..||:.:::|.|
  Fly   136 GRYFSQLVNLKKHKLGHLNAKPYQCNYCEKGFTQLSNFKRHLQSHIKEGVDVDVPASIQAAAALA 200

  Fly   457 SSRNQNASARKESARKQQQIPESFSLDSVELEQTKVLEECIVAN-------DFMFNE----EDN- 509
            ..|                         :|.||.....||:|..       |:..:|    ||:
  Fly   201 RER-------------------------LESEQKPSFFECMVCRAIFDTFADYEKHEAKCHEDHE 240

  Fly   510 -AEQEANDREGLQHDDSYPYVGGYQSVDSVKELVGDLLDTEEFCDESKY 557
             |:.|.|....:..||..|          :|..|.| |||.|...|:.:
  Fly   241 RAQLEVNQMSHMHPDDYLP----------MKFAVPD-LDTHEIIIETTH 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9215	NP_573045.1	zf-AD	16..92	CDD:285071
		DUF2117	165..>273	CDD:303038
		COG5048	<303..439	CDD:227381	47/135 (35%)
		C2H2 Zn finger	307..327	CDD:275368	5/19 (26%)
		zf-H2C2_2	319..344	CDD:290200	12/24 (50%)
		zf-C2H2	333..355	CDD:278523	9/21 (43%)
		C2H2 Zn finger	335..355	CDD:275368	9/19 (47%)
		zf-H2C2_2	347..371	CDD:290200	9/23 (39%)
		C2H2 Zn finger	363..383	CDD:275368	5/19 (26%)
		zf-H2C2_2	375..400	CDD:290200	10/24 (42%)
		C2H2 Zn finger	391..411	CDD:275368	5/19 (26%)
		zf-H2C2_2	404..427	CDD:290200	9/22 (41%)
		C2H2 Zn finger	419..439	CDD:275368	7/19 (37%)
CG17385	NP_001286418.1	COG5048	<13..181	CDD:227381	55/167 (33%)
		C2H2 Zn finger	18..39	CDD:275368	5/20 (25%)
		C2H2 Zn finger	48..68	CDD:275368	5/19 (26%)
		C2H2 Zn finger	76..96	CDD:275368	9/19 (47%)
		C2H2 Zn finger	104..124	CDD:275368	5/19 (26%)
		C2H2 Zn finger	132..148	CDD:275368	4/15 (27%)
		C2H2 Zn finger	160..180	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910