Protein Alignment CG9215 and ZNF543

DIOPT Version :10

• Sequence 1: NP_573045.1
• Gene: CG9215 / 32494
• FlyBaseID: FBgn0030659
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_998763.2
• Gene: ZNF543 / 125919
• HGNCID: 25281
• Length: 600
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 82/328 - (25%)
• Similarity: 135/328 - (41%)
• Gaps: 83/328 - (25%)

  Fly   159 ITTSTEPSEDVKEEKTD---SLSLIPDGAMVLSLNDFQAQDSITQQAEEKDPKKQQDEDEGQAKM 220
            ::.|:.|.::.|.:.|:   |...:|:..::        |:.:||.|.:.....|..:.:|.::|
Human    74 LSQSSYPGDNTKPKTTEPTFSHLALPEEVLL--------QEQLTQGASKNSQLGQSKDQDGPSEM 130

  Fly   221 LE--------------LDPWDDE-------------------NTPEHLYEIETPLIEESVVASPP 252
            .|              |:....|                   :|...|||.::
Human   131 QEVHLKIGIGPQRGKLLEKMSSERDGLGSDDGVCTKITQKQVSTEGDLYECDS------------ 183

  Fly   253 LPLPPTHPANQQKKRTY---------RRVSPNVKHEKLTANVDDDFKAGSTTKRRNCERSPKICD 308
             ..|.|....:::|.:|         ::.:..|:||::...|                 .|..|.
Human   184 -HGPVTDALIREEKNSYKCEECGKVFKKNALLVQHERIHTQV-----------------KPYECT 230

  Fly   309 VCGNTYKYQHALNAHMRRHNNERPYSCEVCQKAFISNVELRRHMRVHTGQKPYSCRHCERRFSDF 373
            .||.|:.....|..|:..|..|:||.|..|.|||.....|.||.|:|:|:|||.|..|.:.|:..
Human   231 ECGKTFSKSTHLLQHLIIHTGEKPYKCMECGKAFNRRSHLTRHQRIHSGEKPYKCSECGKAFTHR 295

  Fly   374 GSSKKHERIHTGERPYVCEVCNKGFAYAHVLSAHRRTHTGKKQFQCTQCDKGFTKKTYLSAHMEQ 438
            .:...|.|.||||:|:||:.|.|.|........|...|||:|.::|.:|.|.|.:::||:.|.:.
Human   296 STFVLHHRSHTGEKPFVCKECGKAFRDRPGFIRHYIIHTGEKPYECIECGKAFNRRSYLTWHQQI 360

  Fly   439 HRG 441
            |.|
Human   361 HTG 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9215	NP_573045.1	zf-AD	16..92	CDD:462262
		COG5048	<303..439	CDD:227381	52/135 (39%)
		C2H2 Zn finger	307..327	CDD:275368	6/19 (32%)
		C2H2 Zn finger	335..355	CDD:275368	9/19 (47%)
		zf-H2C2_2	347..371	CDD:463886	11/23 (48%)
		C2H2 Zn finger	363..383	CDD:275368	5/19 (26%)
		C2H2 Zn finger	391..411	CDD:275368	5/19 (26%)
		C2H2 Zn finger	419..439	CDD:275368	7/19 (37%)
ZNF543	NP_998763.2	KRAB	9..69	CDD:214630
		COG5048	<75..329	CDD:227381	68/291 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..131		4/20 (20%)
		C2H2 Zn finger	201..221	CDD:275368	3/19 (16%)
		COG5048	223..562	CDD:227381	55/158 (35%)
		C2H2 Zn finger	229..249	CDD:275368	6/19 (32%)
		C2H2 Zn finger	257..277	CDD:275368	9/19 (47%)
		C2H2 Zn finger	285..305	CDD:275368	5/19 (26%)
		C2H2 Zn finger	313..333	CDD:275368	5/19 (26%)
		C2H2 Zn finger	341..361	CDD:275368	7/19 (37%)
		C2H2 Zn finger	369..389	CDD:275368
		C2H2 Zn finger	397..417	CDD:275368
		C2H2 Zn finger	425..445	CDD:275368
		C2H2 Zn finger	453..473	CDD:275368
		C2H2 Zn finger	481..501	CDD:275368
		C2H2 Zn finger	509..529	CDD:275368
		C2H2 Zn finger	537..557	CDD:275368