DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7872 and DNAJB12

DIOPT Version :9

Sequence 1:	NP_573044.1	Gene:	CG7872 / 32493	FlyBaseID:	FBgn0030658	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_001352009.1	Gene:	DNAJB12 / 54788	HGNCID:	14891	Length:	377	Species:	Homo sapiens

Alignment Length:	321	Identity:	77/321 - (23%)
Similarity:	120/321 - (37%)	Gaps:	98/321 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 YDVLGVTRESSKSEIGKAYRQLARRYHPDLHRGAEAKAAAETQFKLVATAYEILRDEESRTDYDY 97
            |::|||:|.:|..::.||||:||.::|||.:....|..|    ||.:.|||.:|.:.|.|..||.
Human   112 YEILGVSRGASDEDLKKAYRRLALKFHPDKNHAPGATEA----FKAIGTAYAVLSNPEKRKQYDQ 172

  Fly    98 MLDNPD--AYYAH----YYRYYRRRVAPKVDVRVVIVVVLTIVSVIQYYSGWQRYDSAIKYFATV 156
            ..|:..  |.:.|    ::|.:...::|:....:.........:|..|.:|..||
Human   173 FGDDKSQAARHGHGHGDFHRGFEADISPEDLFNMFFGGGFPSSNVHVYSNGRMRY---------- 227

  Fly   157 PKYRNQALEIARDEIQEKIQKKGKNRMSKNDQRDELERIIRRVIEEKMDVKGGYAKPTLWDVLWV 221
                                    ....:.|:||.             ...||..       ::|
Human   228 ------------------------TYQQRQDRRDN-------------QGDGGLG-------VFV 248

  Fly   222 QLIICPYTILSFIVWHAQWFWRYTVMKQPYG---REQKLYLIRR---HLGMGQHQFEAQEDKLIE 280
            ||:  |..||..:...:|    ..|...||.   |....::.||   |||:..:    ..|...|
Human   249 QLM--PILILILVSALSQ----LMVSSPPYSLSPRPSVGHIHRRVTDHLGVVYY----VGDTFSE 303

  Fly   281 EYL--HLKLWKR---ENFVA------WKAEQEEEMKKKLAENPRY----KAYRRYMKNHGP 326
            ||.  .||..:|   ::::|      ||   |::.|:.|....||    ..|.|..|...|
Human   304 EYTGSSLKTVERNVEDDYIANLRNNCWK---EKQQKEGLLYRARYFGDTDMYHRAQKMGTP 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7872	NP_573044.1	DnaJ	31..96	CDD:278647	25/62 (40%)
DNAJB12	NP_001352009.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	45..92
		DnaJ	110..>236	CDD:333066	38/161 (24%)
		DUF1977	268..368	CDD:312722	27/101 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910