DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7872 and DNAJB11

DIOPT Version :9

Sequence 1:	NP_573044.1	Gene:	CG7872 / 32493	FlyBaseID:	FBgn0030658	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_057390.1	Gene:	DNAJB11 / 51726	HGNCID:	14889	Length:	358	Species:	Homo sapiens

Alignment Length:	387	Identity:	87/387 - (22%)
Similarity:	141/387 - (36%)	Gaps:	122/387 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LVLLALLPTMALGLLEGLYCGKENCYDVLGVTRESSKSEIGKAYRQLARRYHPDLHRGAEAKAAA 72
            |:||.|:..:..|         .:.|.:|||.|.:|..:|.||||:||.:.|||  |..:...|.
Human    11 LLLLYLIGAVIAG---------RDFYKILGVPRSASIKDIKKAYRKLALQLHPD--RNPDDPQAQ 64

  Fly    73 ETQFKLVATAYEILRDEESRTDYD----------YMLDNPDAYYAHYY-----------RYYRRR 116
            | :|:.:..|||:|.|.|.|..||          :...:.| .::|::           |...|.
Human    65 E-KFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSSHGD-IFSHFFGDFGFMFGGTPRQQDRN 127

  Fly   117 VAPKVDVRVVIVVVLTIVSVIQYYSGWQRYDSAIKYFATVPKYRNQALEI-------ARDEIQEK 174
            :....|:.|.:.|.|.     :.|:|         .|..|.:.:..|.:.       .|.|::..
Human   128 IPRGSDIIVDLEVTLE-----EVYAG---------NFVEVVRNKPVARQAPGKRKCNCRQEMRTT 178

  Fly   175 IQKKGKNRMSKNDQRDELERI----IRRVIEEKMD--VKGGYAKPTLWDVLWVQLIICPYT---- 229
            ....|:.:|::....||...:    ..|.:|.:::  |:.|...|.:.:..       |:.
Human   179 QLGPGRFQMTQEVVCDECPNVKLVNEERTLEVEIEPGVRDGMEYPFIGEGE-------PHVDGEP 236

  Fly   230 -ILSFIVWHAQWFWRYTVMKQPY--GREQKLY------LIRRHLG-------MGQHQFEAQEDKL 278
             .|.|         |..|:|.|.  .|...||      |:...:|       :..|:.....||:
Human   237 GDLRF---------RIKVVKHPIFERRGDDLYTNVTISLVESLVGFEMDITHLDGHKVHISRDKI 292

  Fly   279 IEEYLHLKLWKR----ENF--------------VAWKAEQ-----EEEMKKKLAENPRYKAY 317
            ...  ..||||:    .||              |.:..||     .|.:|:.|.:....|.|
Human   293 TRP--GAKLWKKGEGLPNFDNNNIKGSLIITFDVDFPKEQLTEEAREGIKQLLKQGSVQKVY 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7872	NP_573044.1	DnaJ	31..96	CDD:278647	27/64 (42%)
DNAJB11	NP_057390.1	DnaJ	22..344	CDD:223560	80/366 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910