Protein Alignment HPN and CG7142

DIOPT Version :10

• Sequence 1: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Alignment Length: 340
• Identity: 98/340 - (28%)
• Similarity: 138/340 - (40%)
• Gaps: 93/340 - (27%)

Human   107 RTAGANGTSGFFCVDEGRLPHTQRLLEVISVCDCPR-----GRFLAAICQDCGRRKLPVDRIVGG 166
            |:|||..|........|.|.:.      ||..:.||     .:|||.
  Fly    43 RSAGAAHTMAMNLAAYGLLENR------ISTLEAPRQTHWTKKFLAK------------------ 83

Human   167 RDTSLGRWPWQVSLRY----DG-AHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQAS 226
            |:.:....|:.||::.    .| .|.|.|::::..|:||||||       ||..:....:|..|.
  Fly    84 REATPHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHC-------LSSPQAVENSVIVAG 141

Human   227 PHGL--QLG-------------VQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPV 276
            .|.:  |.|             |:..:|.||..|:          ||||::...||....|:||.
  Fly   142 SHDIHDQKGEASNIQMRHIDYYVRHELYLGGVNPY----------DIALIYTKEPLVFDTYVQPA 196

Human   277 CLPAAGQALVDGKICTVTGWGNTQY-----YGQQAGVLQEARVPIISNDVC------NGADFYGN 330
            .||.. .|..:| ..|:.||||...     |..:   ||||.:||:..::|      :|...:..
  Fly   197 TLPEQ-DAQPEG-YGTLYGWGNVSMTAVPNYPHR---LQEANMPILDMELCEQILARSGLPLHET 256

Human   331 QIKPKMFCAGYPEGGIDACQGDSGGPFV---CEDSISRTPRWRLCGIVSWG-TGCALAQKPGVYT 391
            .:     |.|...||:..|..|||||.:   ||:...:..  .:.|||||| ..|.....|.|:.
  Fly   257 NL-----CTGPLTGGVSICTADSGGPLIQQCCEEHFEQAN--IVIGIVSWGKMPCGQKNAPSVFV 314

Human   392 KVSDFREWIFQAIKT 406
            :||.|.|||.|.|.|
  Fly   315 RVSAFTEWINQVIST 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	14/56 (25%)
		Tryp_SPc	163..400	CDD:238113	79/271 (29%)
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	81/270 (30%)