Protein Alignment HPN and CG10405

DIOPT Version :10

• Sequence 1: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_001036717.1
• Gene: CG10405 / 41996
• FlyBaseID: FBgn0038431
• Length: 268
• Species: Drosophila melanogaster
• Alignment Length: 248
• Identity: 82/248 - (33%)
• Similarity: 128/248 - (51%)
• Gaps: 24/248 - (9%)

Human   159 PVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVA 223
            |..|||.||:.:.|::|:|:|||....|:||.|:||.:|.:|||||.....:....:.:..|::.
  Fly    33 PDSRIVNGREATEGQFPYQLSLRRQTVHICGASILSSNWAITAAHCIDGHEQQPREFTLRQGSIM 97

Human   224 QASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSS---PLPLTEYIQPVCLPAAGQAL 285
            :.|...:| .|:|:..|..|      :..:.:.|:||:..:.   .|||.: :.|:.||..|:|:
  Fly    98 RTSGGTVQ-PVKAIYKHPAY------DRADMNFDVALLRTADGALSLPLGK-VAPIRLPTVGEAI 154

Human   286 VDGKICTVTGWGNTQYYGQ-QAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDAC 349
            .:.....|:|||:...... .:.||:...|..::.:.|:....:...:...||||.  ....|||
  Fly   155 SESMPAVVSGWGHMSTSNPVLSSVLKSTTVLTVNQEKCHNDLRHHGGVTEAMFCAA--ARNTDAC 217

Human   350 QGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVS--DFREWI 400
            |||||||...:.:        |.||||||.|||....|||||:::  ..|.||
  Fly   218 QGDSGGPISAQGT--------LIGIVSWGVGCADPYYPGVYTRLAHPTIRRWI 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	82/248 (33%)
		Tryp_SPc	163..400	CDD:238113	78/242 (32%)
CG10405	NP_001036717.1	Tryp_SPc	36..262	CDD:214473	79/243 (33%)